Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Timothy M. Hanley"'
Autor:
Eugene V. Ravkov, Elizabeth S. C. P. Williams, Marc Elgort, Adam P. Barker, Vicente Planelles, Adam M. Spivak, Julio C. Delgado, Leo Lin, Timothy M. Hanley
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
IntroductionThe clinical manifestations of acute severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection and coronavirus disease 2019 (COVID-19) suggest a dysregulation of the host immune response that leads to inflammation, throm
Externí odkaz:
https://doaj.org/article/c52ac4d8929e452ab412db6de5ac603e
Autor:
Laura J. Martins, Matthew A. Szaniawski, Elizabeth S. C. P. Williams, Mayte Coiras, Timothy M. Hanley, Vicente Planelles
Publikováno v:
Pathogens, Vol 11, Iss 2, p 163 (2022)
HIV-1 infection of myeloid cells is associated with the induction of an IFN response. How HIV-1 manipulates and subverts the IFN response is of key interest for the design of therapeutics to improve immune function and mitigate immune dysregulation i
Externí odkaz:
https://doaj.org/article/3d842d7222654701b250f160f66930eb
Publikováno v:
Journal of Leukocyte Biology. 112:1343-1356
Macrophages chronically infected with HIV-1 serve as a reservoir that contributes to HIV-1 persistence during antiretroviral therapy; however, the mechanisms governing the establishment and maintenance of this virus reservoir have not been fully eluc
Autor:
Elizabeth S C P, Williams, Matthew A, Szaniawski, Laura J, Martins, Emily A, Innis, José, Alcamí, Timothy M, Hanley, Adam M, Spivak, Mayte, Coiras, Vicente, Planelles
Publikováno v:
Clin Res HIV AIDS
Macrophages are one of the main cellular targets of human immunodeficiency virus type 1 (HIV-1). Macrophage infection by HIV-1 is inefficient due to the presence of the viral restriction factor sterile alpha motif and histidine aspartic acid domain c
Autor:
Timothy M. Hanley, Archana M. Agarwal
Publikováno v:
Journal of Hematopathology. 13:193-196
Osteopetrosis is a severe and frequently fatal condition characterized by the formation of thick, dense bone, with a concomitant loss of bone marrow spaces secondary to defective osteoclast function or development. Clinical symptoms include pancytope
Publikováno v:
Journal of Virology. 95
Macrophages are infected by HIV-1 in vivo and contribute to both viral spread and pathogenesis. Recent human and animal studies suggest that HIV-1-infected macrophages serve as a reservoir that contributes to HIV-1 persistence during anti-retroviral
Publikováno v:
Journal of Virology
The major barrier toward the eradication of HIV-1 infection is the presence of a small reservoir of latently infected cells, which include CD4+ T cells and macrophages that escape immune-mediated clearance and the effects of antiretroviral therapy. T
Macrophages are infected by HIV-1 in vivo and contribute to both viral spread and pathogenesis. Recent human and animal studies suggest that HIV-1-infected macrophages serve as a reservoir that contributes to HIV-1 persistence during anti-retroviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635be0d09e14d1e600de24e4dbef06e3
https://doi.org/10.1101/2020.05.18.103333
https://doi.org/10.1101/2020.05.18.103333
Autor:
Timothy M. Hanley, Jonathan L. Catrow, Vicente Planelles, Matthew A. Szaniawski, James E. Cox, Alberto Bosque, Elizabeth S. C. P. Williams, Adam M. Spivak, Michel J. Tremblay
Publikováno v:
mBio
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00819-18 (2018)
mBio, Vol 9, Iss 3 (2018)
mBio, Vol 9, Iss 3, p e00819-18 (2018)
Macrophages are susceptible to human immunodeficiency virus type 1 (HIV-1) infection despite abundant expression of antiviral proteins. Perhaps the most important antiviral protein is the restriction factor sterile alpha motif domain and histidine/as
Autor:
Andrew G. Ramstead, Timothy M. Hanley, Thomas B. Huffaker, Laura L. Dickey, Thomas E. Lane, Ryan M. O'Connell
Publikováno v:
Journal of Neuroimmunology
MicroRNA (miRNA) regulation of gene expression is becoming an increasingly recognized mechanism by which host immune responses are governed following microbial infection. miRNAs are short, non-coding RNAs that repress translation of target genes, and