Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Timothy M. E. Scales"'
Autor:
Maddy Parsons, Timothy M E Scales
Publikováno v:
Current Opinion in Cell Biology. 23:562-568
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4fe31278ee71465d89f72c21127fbb7
https://doi.org/10.1016/j.ceb.2011.05.008
https://doi.org/10.1016/j.ceb.2011.05.008
Autor:
Timothy M E Scales, Daniel C. Worth, Gareth E. Jones, Maddy Parsons, Samantha J King, James Monypenny
Publikováno v:
The EMBO Journal. 30:1705-1718
Chemotactic migration of fibroblasts towards growth factors, such as during development and wound healing, requires precise spatial coordination of receptor signalling. However, the mechanisms regulating this remain poorly understood. Here, we demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cab9df0a4d9876d2ec25e1863c5e25bd
https://doi.org/10.1038/emboj.2011.82
https://doi.org/10.1038/emboj.2011.82
Autor:
Pascal Derkinderen, Wendy Noble, Charles Duyckaerts, Diane P. Hanger, C. Hugh Reynolds, Timothy M. E. Scales, Ritchie Williamson, Brian H. Anderton, Thibaud Lebouvier
Publikováno v:
Journal of Alzheimer's Disease. 18:1-9
Tau protein is the principal component of the neurofibrillary tangles found in Alzheimer's disease (AD), where it is hyperphosphorylated on serine and threonine residues. It is hypothesized that this hyperphosphorylation contributes to neurodegenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b6c0f9c9cfa0db8d9f20fde01e399d
https://doi.org/10.3233/jad-2009-1116
https://doi.org/10.3233/jad-2009-1116
Autor:
Brian H. Anderton, C. Hugh Reynolds, Diane P. Hanger, Thibaud Lebouvier, Timothy M. E. Scales, Robert L. Geahlen, Bernard Lardeux, Pascal Derkinderen
Publikováno v:
Biochimica et Biophysica Acta
Aberrant phosphorylation of tau protein on serine and threonine residues has been shown to be critical in neurodegenerative disorders called tauopathies. An increasing amount of data suggest that tyrosine phosphorylation of tau might play an equally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d692242b44859c3d2a3f9340ede314
Publikováno v:
Molecular and cellular neurosciences. 49(2)
The microtubule-associated protein MAP1B is known to have important roles in neuronal development, particularly during neuronal migration and axonogenesis, but its precise molecular actions are unknown. We used RNA interference silencing of protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34ca66ba9826598a603dd72a96ac12fd
https://pubmed.ncbi.nlm.nih.gov/22033417
https://pubmed.ncbi.nlm.nih.gov/22033417
Autor:
Timothy M. E. Scales, Caroline Price, C. Hugh Reynolds, Malcolm Ward, Timothy Perera, Ritchie Williamson, Brian H. Anderton, Pascal Derkinderen, Stuart Kellie, Helen Byers, Kit-Yi Leung, Ian N. Bird
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 12 (2011)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Tau protein is the principal component of the neurofibrillary tangles found in Alzheimer's disease, where it is hyperphosphorylated on serine and threonine residues, and recently phosphotyrosine has been demonstrated. The Src-family kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac348c93ab4264d48c9298fb877dc9b8
http://www.molecularneurodegeneration.com/content/6/1/12
http://www.molecularneurodegeneration.com/content/6/1/12
MAP1B is a developmentally regulated microtubule-associated phosphoprotein that regulates microtubule dynamics in growing axons and growth cones. We used mass spectrometry to map 28 phosphorylation sites on MAP1B, and selected for further study a put
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f55ada434e9fa9fa72a8118a31bb9f5e
https://europepmc.org/articles/PMC2704879/
https://europepmc.org/articles/PMC2704879/
