Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Timothy M Stearns"'
Autor:
Ramani Soundararajan, Helena Hernández-Cuervo, Timothy M Stearns, Anthony J Griswold, Sahebgowda Sidramagowda Patil, Jutaro Fukumoto, Venkata Ramireddy Narala, Lakshmi Galam, Richard Lockey, Narasaiah Kolliputi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Critically ill patients on supplemental oxygen therapy eventually develop acute lung injury (ALI). Reactive oxygen species (ROS) produced during ALI perturbs the mitochondrial dynamics resulting in cellular damage. Genetic deletion of the
Externí odkaz:
https://doaj.org/article/60d6092c74c549c8962d337265289e32
Autor:
Judith L Morgan, Karen L Svenson, Jeffrey P Lake, Weidong Zhang, Timothy M Stearns, Michael A Marion, Luanne L Peters, Beverly Paigen, Leah Rae Donahue
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90012 (2014)
To evaluate the effect of increased mouse density in a cage, mice were housed at the density recommended by the 1996 Guide for the Care and Use of Laboratory Animals and at densities that were approximately 2, 2.6, and 3 times greater. Five strains o
Externí odkaz:
https://doaj.org/article/858859379408442b8f3b48f742f5759b
Autor:
Ramani Soundararajan, Jungyeon Won, Timothy M Stearns, Jeremy R Charette, Wanda L Hicks, Gayle B Collin, Jürgen K Naggert, Mark P Krebs, Patsy M Nishina
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110299 (2014)
Mutations in the membrane frizzled-related protein (MFRP/Mfrp) gene, specifically expressed in the retinal pigment epithelium (RPE) and ciliary body, cause nanophthalmia or posterior microphthalmia with retinitis pigmentosa in humans, and photorecept
Externí odkaz:
https://doaj.org/article/434f634475b741999deb8a83c8342dfb
Autor:
John P Sundberg, Timothy M Stearns, Joongho Joh, Mary Proctor, Arvind Ingle, Kathleen A Silva, Soheil S Dadras, A Bennett Jenson, Shin-je Ghim
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113582 (2014)
Papillomaviruses (PVs) induce papillomas, premalignant lesions, and carcinomas in a wide variety of species. PVs are classified first based on their host and tissue tropism and then their genomic diversities. A laboratory mouse papillomavirus, MmuPV1
Externí odkaz:
https://doaj.org/article/cc758755f4da484ca7dcb79b0e0af420
Autor:
Christopher S Potter, Zhe Wang, Kathleen A Silva, Victoria E Kennedy, Timothy M Stearns, Lisa Burzenski, Leonard D Shultz, Harm Hogenesch, John P Sundberg
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85666 (2014)
SHARPIN is a key regulator of NFKB and integrin signaling. Mice lacking Sharpin develop a phenotype known as chronic proliferative dermatitis (CPDM), typified by progressive epidermal hyperplasia, apoptosis of keratinocytes, cutaneous and systemic eo
Externí odkaz:
https://doaj.org/article/32d0a138b4264dcca4e15fba7dbc4e91
Autor:
Anne R Greenlee, Meng-Shin Shiao, Elizabeth Snyder, F William Buaas, Tongjun Gu, Timothy M Stearns, Manju Sharma, Elizabeth P Murchison, Gabriella C Puente, Robert E Braun
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46359 (2012)
MicroRNAs (miRNAs) are a class of endogenous, non-coding RNAs that mediate post-transcriptional gene silencing by inhibiting mRNA translation and promoting mRNA decay. DICER1, an RNase III endonuclease encoded by Dicer1, is required for processing sh
Externí odkaz:
https://doaj.org/article/4d91b14f715944f5ba42139b4d96e81d
Autor:
Jennifer J. Trowbridge, Grant A. Challen, Timothy M. Stearns, Logan S. Schwartz, Kristina D. Mujica, Jayna J. Mistry, Kira A. Young, Matthew A. Loberg, Elizabeth Eudy, Jennifer M. SanMiguel
Clonal hematopoiesis resulting from the enhanced fitness of mutant hematopoietic stem cells (HSC) associates with both favorable and unfavorable health outcomes related to the types of mature mutant blood cells produced, but how this lineage output i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7f7a21e96cf495b84841121be73722
https://doi.org/10.1158/2159-8290.c.6549771.v1
https://doi.org/10.1158/2159-8290.c.6549771.v1
Autor:
Jennifer J. Trowbridge, Grant A. Challen, Timothy M. Stearns, Logan S. Schwartz, Kristina D. Mujica, Jayna J. Mistry, Kira A. Young, Matthew A. Loberg, Elizabeth Eudy, Jennifer M. SanMiguel
Supplementary Table from Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d31af7a1d42a11622f5574145b29ff
https://doi.org/10.1158/2159-8290.22541943
https://doi.org/10.1158/2159-8290.22541943
Autor:
Jennifer J. Trowbridge, Grant A. Challen, Timothy M. Stearns, Logan S. Schwartz, Kristina D. Mujica, Jayna J. Mistry, Kira A. Young, Matthew A. Loberg, Elizabeth Eudy, Jennifer M. SanMiguel
Supplementary Figure from Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68e5687f5dde5659afc0844c64ba40dc
https://doi.org/10.1158/2159-8290.22541946
https://doi.org/10.1158/2159-8290.22541946
Autor:
Kyuson Yun, Jeong K. Yoon, Susan L. Ackerman, Roderick T. Bronson, Timothy M. Stearns, Michael D. Taylor, David J. Shih, Emily E. Miller, Yaochen Li, Sivaraman Natarajan
PDF file - 65K, Supplementary Figure 6. A schematic drawing of full length N1ICD in mouse, N1ICD allele analyzed in this study, and the ACTB-Notch1 allele previously published (Yang et al., 2004) and analyzed in Supplementary Figure 6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d19da1cb4ea06fda60fd764a78e719
https://doi.org/10.1158/0008-5472.22398012.v1
https://doi.org/10.1158/0008-5472.22398012.v1