Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Timothy M Schmitt"'
Autor:
Jing Jin, Le Tra Giang Nguyen, Andrew Wassef, Ragui Sadek, Timothy M. Schmitt, Grace L. Guo, Theodore P. Rasmussen, Xiao-bo Zhong
Publikováno v:
Non-Coding RNA, Vol 10, Iss 2, p 28 (2024)
The long non-coding RNA (lncRNA) hepatocyte nuclear factor-1 alpha (HNF1A) antisense RNA 1 (HNF1A-AS1) is an important lncRNA for liver growth, development, cell differentiation, and drug metabolism. Like many lncRNAs, HNF1A-AS1 has multiple annotate
Externí odkaz:
https://doaj.org/article/0ce28de94ac0487eb880b5c3eeb91e98
Publikováno v:
Current Colorectal Cancer Reports. 18:39-44
Publikováno v:
Annals of Hepatology, Vol 9, Iss 4, Pp 390-396 (2010)
Background. Restrictive staging criteria for liver transplant (LT) patients with HCC in the U.S. have resulted in favorable long-term recurrence-free survival, but these criteria exclude a subgroup of patients who, despite tumor size beyond T2 stage,
Externí odkaz:
https://doaj.org/article/e9a5f41005e248be9f788b935bc6f75b
Autor:
Sean C. Kumer, Prasad Dandawate, Timothy M. Schmitt, Rashna Madan, Timothy McGinnis, Ravi Kumar Paluri, Leonidas E. Bantis, Anup Kasi
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 3102, p 3102 (2020)
Journal of Clinical Medicine
Volume 9
Issue 10
Journal of Clinical Medicine
Volume 9
Issue 10
Pancreatic intraepithelial neoplasms (PanINs) and intraductal papillary mucinous neoplasms (IPMNs) are common pancreatic adenocarcinoma precursor lesions. However, data regarding their respective associations with survival rate and prognosis are lack
Autor:
Sean C. Kumer, C. David Williams, Bartholomew Kane, Hong-Min Ni, Benjamin L. Woolbright, Timothy M. Schmitt, Hartmut Jaeschke
Publikováno v:
Toxicon. 125:99-109
Microcystins are a group of toxins produced by freshwater cyanobacteria. Uptake of microcystin-leucine arginine (MC-LR) by organic anion transporting polypeptide 1B2 in hepatocytes results in inhibition of protein phosphatase 1A and 2A, and subsequen
Autor:
Akshay Middiniti, Weijing Sun, Anup Kasi, Mohammed Al-Jumayli, Sean C. Kumer, Anusha Chidharla, Anwaar Saeed, Joaquina Baranda, Timothy M. Schmitt, Raed Al-Rajabi, Amna Batool
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2019 (2019)
Journal of Oncology, Vol 2019 (2019)
Introduction. Ampullary cancers represent a subset of periampullary cancers, comprising only 0.2% all gastrointestinal cancers. Localized disease is primarily managed by a surgical intervention, called pancreaticoduodenectomy (PD), followed in many c
Autor:
Pal Pacher, Hua Wang, Anna S. Gukovskaya, Sean C. Kumer, Robert C. De Lisle, Shaogui Wang, Olga A. Mareninova, Brian Bridges, Hong-Min Ni, Andrea Ballabio, Xiaojuan Chao, Wen-Xing Ding, Timothy M. Schmitt
Publikováno v:
Autophagy. 15(11)
Impaired macroautophagy/autophagy has been implicated in experimental and human pancreatitis. However, the transcriptional control governing the autophagy-lysosomal process in pancreatitis is largely unknown. We investigated the role and mechanisms o
Autor:
Connie J. Wang, Aditi Gupta, Michael Brimacombe, Daniel Murillo, Atta Nawabi, Sri G. Yarlagadda, Timothy M. Schmitt, Christopher F. Bryan
Publikováno v:
Transplant Immunology. 37:18-22
Human leukocyte antigens (HLA) class II donor-specific antibodies (DSAs) are associated with microcirculation inflammation, transplant glomerulopathy and ultimately graft loss. There is however no data on allograft outcomes in deceased donor kidney t
Autor:
Timothy M. Schmitt, James P. Luyendyk, Atta Nawabi, Cheryl E Rockwell, Timothy R. Zacharewski, Matthew J. Flick, Rance Nault, Nikita Joshi, Jessica L. Ray, Holly Cline-Fedewa, Anna K. Kopec
Publikováno v:
Blood. 127:2751-2762
Coagulation cascade activation and fibrin deposits have been implicated or observed in diverse forms of liver damage. Given that fibrin amplifies pathological inflammation in several diseases through the integrin receptor αMβ2, we tested the hypoth
Autor:
Yuchao Xie, Wen-Xing Ding, Kenneth Dorko, Sean C. Kumer, Mitchell R. McGill, Hartmut Jaeschke, Kuo Du, Timothy M. Schmitt
Publikováno v:
Toxicology and Applied Pharmacology. 289:213-222
3'-Hydroxyacetanilide orN-acetyl-meta-aminophenol (AMAP) is generally regarded as a non-hepatotoxic analog of acetaminophen (APAP). Previous studies demonstrated the absence of toxicity after AMAP in mice, hamsters, primary mouse hepatocytes and seve