Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Timothy M Barrow"'
Autor:
Chanachai Sae-Lee, Julien De Biasi, Natassia Robinson, Timothy M Barrow, John C Mathers, Georgios Koutsidis, Hyang-Min Byun
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234578 (2020)
The identification of early markers of dementia is important for higher-risk populations such as those with type 2 diabetes (T2D). Retrotransposons, including long interspersed nuclear element 1 (LINE-1) and Alu, comprise ~40% of the human genome. Al
Externí odkaz:
https://doaj.org/article/2353584655294dee8756d54426ecbd25
Autor:
Akin Cayir, Timothy M Barrow, Hao Wang, Hongbin Liu, Changping Li, Ning Ding, Yan Li, Choong-Min Kang, Liqiong Guo, Peng-Hui Li, Hyang-Min Byun
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209041 (2018)
ObjectivesWe investigated the association between occupational noise exposure and the risk of elevated blood pressure and hypertension by stage in young adults.MethodsWe utilized 124,286 young adults (18-40 years) from the Project ELEFANT study. We c
Externí odkaz:
https://doaj.org/article/268f8c40203e4f9ebe984fb0ef142ecd
Autor:
Hui Xu, Peng-Hui Li, Timothy M Barrow, Elena Colicino, Changping Li, Ruixue Song, Hongbin Liu, Nai-Jun Tang, Songyan Liu, Liqiong Guo, Hyang-Min Byun
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0207929 (2018)
BackgroundThe menstrual cycle is regulated by reproductive hormones such as estrogen which has been implicated in the pathogenesis of hypertension and is associated with obesity. However, to date there has scant study of hypertension in relation to m
Externí odkaz:
https://doaj.org/article/65e0e3ce7dd54cc4baa172f216810330
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionEpigenetic marks have been proposed as early changes, at the subcellular level, in disease development. To find more specific biomarkers of effect in occupational exposures to toxicants, DNA methylation studies in peripheral blood cells h
Externí odkaz:
https://doaj.org/article/f55a9259c89b4dca85546c8a4651daa9
Autor:
Liqiong Guo, Cheng Peng, Hui Xu, Ander Wilson, Peng-hui Li, Hao Wang, Hongbin Liu, Lilin Shen, Xi Chen, Xiuying Qi, Nai-jun Tang, Timothy M. Barrow, Hyang-Min Byun
Publikováno v:
BMC Women's Health, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Early and late age at menarche are associated with risk of hypertension, but little is known whether modifiable lifestyle can reduce this risk. Methods Our study leverages 60,135 healthy young Chinese women from the Environmental
Externí odkaz:
https://doaj.org/article/10f8cb54dcc84c62961f5e1d8ccbee9a
Autor:
Timothy M. Barrow, Hyang-Min Byun, Xinyan Li, Chris Smart, Yong-Xiang Wang, Yacong Zhang, Andrea A. Baccarelli, Liqiong Guo
Publikováno v:
Epigenetics, Vol 12, Iss 12, Pp 1038-1047 (2017)
Morphine is one of the most effective analgesics in medicine. However, its use is associated with the development of tolerance and dependence. Recent studies demonstrating epigenetic changes in the brain after exposure to opiates have provided insigh
Externí odkaz:
https://doaj.org/article/129d6586eec84330bdc04b3059c30136
Autor:
Timothy M. Barrow, Nicole Wong Doo, Roger L. Milne, Graham G. Giles, Elaine Willmore, Gordon Strathdee, Hyang-Min Byun
Publikováno v:
Haematologica, Vol 106, Iss 1 (2020)
Retrotransposons such as LINE-1 and Alu comprise >25% of the human genome. While global hypomethylation of these elements has been widely reported in solid tumours, their epigenetic dysregulation is yet to be characterised in chronic lymphocytic leuk
Externí odkaz:
https://doaj.org/article/e8949d04e2564482af80b14115a12b8c
Autor:
Chanachai Sae-Lee, Timothy M. Barrow, Elena Colicino, Si Ho Choi, Yoana Rabanal-Ruiz, Daniel Green, Viktor I. Korolchuk, John C. Mathers, Hyang-Min Byun
Publikováno v:
Clinical epigenetics. 14(1)
Background DNA methylation in the human genome is established and maintained by DNA methyltransferases (DNMTs). DNMT isoforms show differential expression by cell lineage and during development, but much remains to be elucidated about their shared an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10020d458cbe6f2a0d9d6c93e4a9cf16
https://pubmed.ncbi.nlm.nih.gov/35987848
https://pubmed.ncbi.nlm.nih.gov/35987848
Publikováno v:
Oncogene
The identification of cancer-specific vulnerability genes is one of the most promising approaches for developing more effective and less toxic cancer treatments. Cancer genomes exhibit thousands of changes in DNA methylation and gene expression, with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::139bbb330afe46fdde74a395e682451a
http://sure.sunderland.ac.uk/id/eprint/13736/1/13736.pdf
http://sure.sunderland.ac.uk/id/eprint/13736/1/13736.pdf
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
With the rapid process of industrialization and the growth of the human population to unprecedented levels, individuals are increasingly exposed to multiple pollutants known to have an adverse impact upon human health, such as heavy metals, endocrine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8a4d82ed21640241908344ff16033a
https://www.frontiersin.org/articles/10.3389/fgene.2021.694288/full
https://www.frontiersin.org/articles/10.3389/fgene.2021.694288/full