Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Timothy Lawlor"'
Autor:
Timothy Lawlor
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 519:5373-5383
Late thermal pulse (LTP) stellar evolution models experience a helium pulse that occurs following asymptotic giant branch (AGB) departure and causes a rapid looping evolution in the Hertzsprung–Russell (HR) diagram between the AGB and planetary neb
Combination comet/micronucleus assay validation performed by BioReliance under the JaCVAM initiative
Autor:
Jamie E. Sly, Michelle L. Klug La Force, Shannon W. Bruce, Marilyn J. Aardema, Samuel Atta-Safoh, Ljubica Krsmanovic, Sandra Springer, Mirna Arevalo, Fekadu Debelie, Tawney Kelley, Madhav Paranjpe, Timothy Lawlor, Kamala Pant
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. :87-97
In the international validation study of the in vivo rat alkaline comet assay (comet assay), the Japanese Center for the Validation of Alternative Methods (JaCVAM) provided three coded chemicals to BioReliance, 1,3-dichloropropene, ethionamide and bu
Autor:
Yong Xu, Kamala Pant, Shambhu K Roy, Marilyn J. Aardema, Reem Elbekai, Timothy Lawlor, Leon F. Stankowski
Publikováno v:
Mutagenesis. 30:335-342
As part of the international Pig-a validation trials, we examined the induction of Pig-a mutant reticulocytes and red blood cells (RET(CD59-) and RBC(CD59-), respectively) in peripheral blood of male Sprague Dawley(®) rats treated with urethane (25,
Autor:
Timothy Lawlor, Sandra Springer, Kamala Pant, Shannon W. Bruce, Marilyn J. Aardema, Nicola J. Hewitt
Publikováno v:
Environmental and Molecular Mutagenesis. 55:633-642
There is increased interest in the in vivo comet assay in rodents as a follow-up approach for determining the biological relevance of chemicals that are genotoxic in in vitro assays. This is partly because, unlike other assays, DNA damage can be asse
Autor:
Valentine O Wagner, Kamala Pant, Robert R. Young, Jane J. Clarke, Wannie Madraymootoo, Timothy Lawlor, Marilyn J. Aardema
Publikováno v:
Environmental and Molecular Mutagenesis. 53:631-635
Key modifications to in vitro genetic toxicology testing have been made in the last 5 years including the use of optimization approaches such as structure–activity relationships and screening assays to identify and eliminate potentially genotoxic c
Autor:
Robert Young, Marilyn Aardema, Valentine Wagner III, Jane Clarke, Rohan Kulkarni, Shambhu Roy, Yong Xu, Kamala Pant, Leon Stankowski Jr., Timothy Lawlor
Publikováno v:
Handbook of Toxicology, Third Edition ISBN: 9781439890134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88fceb3a5cadeefcee1c2e498b8daa94
https://doi.org/10.1201/b16632-14
https://doi.org/10.1201/b16632-14
Autor:
Robert Young, Harshini Dinesdurage, David Bruning, Leon Stankowski, Rohan Kulkarni, Timothy Lawlor, Marie McKeon, Yong Xu, Svetlana Avlasevich, Dorothea Torous, Stephen Dertinger, Marilyn Aardema
Publikováno v:
Toxicology Letters. 229:S56-S57
Publikováno v:
Mutation research. 370(1)
Autor:
David J. Doolittle, Victoria M. Payne, Timothy Lawlor, Carr J. Smith, Asim Kumar Debnath, Corwin Hansch
Publikováno v:
Mutation research. 279(1)
26 synthetic and naturally occurring heterocyclic amines were tested in the Salmonella/microsome assay (Ames test) using tester strains TA98 and TA100 in the presence of an Aroclor-induced rat-liver S9 fraction. 9 of the compounds were protein-pyroly
Publikováno v:
Environmental and molecular mutagenesis. 19
311 chemicals were tested under code, for mutagenicity, in Salmonella typhimurium; 35 of the chemicals were tested more than once in the same or different laboratories. The tests were conducted using a preincubation protocol in the absence of exogeno