Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Timothy L. Kline"'
Publikováno v:
Frontiers in Radiology, Vol 3 (2023)
IntroductionMethods that automatically flag poor performing predictions are drastically needed to safely implement machine learning workflows into clinical practice as well as to identify difficult cases during model training.MethodsDisagreement betw
Externí odkaz:
https://doaj.org/article/6a649f3b3c4a4b2e959a4280b2da568b
Autor:
Dalia Zubidat, Christian Hanna, Amarjyot K. Randhawa, Byron H. Smith, Maroun Chedid, Daniel-Hasan N. Kaidbay, Luca Nardelli, Yaman G. Mkhaimer, Reem M. Neal, Charles D. Madsen, Sarah R. Senum, Adriana V. Gregory, Timothy L. Kline, Ziad M. Zoghby, Stephen M. Broski, Naim S. Issa, Peter C. Harris, Vicente E. Torres, Jad G. Sfeir, Fouad T. Chebib
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101655- (2023)
ADPKD is caused by pathogenic variants in PKD1 or PKD2, encoding polycystin-1 and -2 proteins. Polycystins are expressed in osteoblasts and chondrocytes in animal models, and loss of function is associated with low bone mineral density (BMD) and volu
Externí odkaz:
https://doaj.org/article/f14b4e1338eb4ca6b2a406927c9c0dc0
Autor:
Anna Caroli, Timothy L. Kline
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 15, p 5133 (2023)
In the context of autosomal dominant polycystic kidney disease (ADPKD), measurement of the total kidney volume (TKV) is crucial. It acts as a marker for tracking disease progression, and evaluating the effectiveness of treatment strategies. The TKV h
Externí odkaz:
https://doaj.org/article/962ab131d55547ecbc8c5cfe28b38079
Autor:
Katharina Hopp, Victoria A. Catenacci, Nidhi Dwivedi, Timothy L. Kline, Wei Wang, Zhiying You, Dustin T. Nguyen, Kristen Bing, Bhavya Poudyal, Ginger C. Johnson, Matthew R. Jackman, Marsha Miller, Cortney N. Steele, Natalie J. Serkova, Paul S. MacLean, Raphael A. Nemenoff, Berenice Gitomer, Michel Chonchol, Kristen L. Nowak
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103697- (2022)
Summary: Progression of autosomal dominant polycystic kidney disease (ADPKD) is modified by metabolic defects and obesity. Indeed, reduced food intake slows cyst growth in preclinical rodent studies. Here, we demonstrate the feasibility of daily calo
Externí odkaz:
https://doaj.org/article/01786711dc38457a958b92ee0aa73814
Autor:
Yoshihiko Yu, Kate L. Shumway, Jodi S. Matheson, Marie E. Edwards, Timothy L. Kline, Leslie A. Lyons
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-11 (2019)
Abstract Background Approximately 30% of Persian cats have a c.10063C > A variant in polycystin 1 (PKD1) homolog causing autosomal dominant polycystic kidney disease (ADPKD). The variant is lethal in utero when in the homozygous state and is the only
Externí odkaz:
https://doaj.org/article/cdf5f3158f50427a9cb20b1957df3761
Autor:
Tatsuya Suwabe, Alanna M. Chamberlain, Jill M. Killian, Bernard F. King, Adriana V. Gregory, Charles D. Madsen, Xiaofang Wang, Timothy L. Kline, Fouad T. Chebib, Marie C. Hogan, Patrick S. Kamath, Peter C. Harris, Vicente E. Torres
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100166- (2020)
Background & Aims: Isolated autosomal-dominant polycystic liver disease (ADPLD) is generally considered a rare disease. However, the frequency of truncating mutations to ADPLD genes in large, population sequencing databases is 1:496. With the increas
Externí odkaz:
https://doaj.org/article/b0a46e63d2e441f8913c41529029e50d
Autor:
Theodora A. Potretzke, Panagiotis Korfiatis, Daniel J. Blezek, Marie E. Edwards, Jason R. Klug, Cole J. Cook, Adriana V. Gregory, Peter C. Harris, Fouad T. Chebib, Marie C. Hogan, Vicente E. Torres, Candice W. Bolan, Kumaresan Sandrasegaran, Akira Kawashima, Jeremy D. Collins, Naoki Takahashi, Robert P. Hartman, Eric E. Williamson, Bernard F. King, Matthew R. Callstrom, Bradley J. Erickson, Timothy L. Kline
Publikováno v:
Mayo Clinic Proceedings. 98:689-700
Autor:
Timothy L. Kline
Publikováno v:
Kidney360. 4:569-571
Autor:
Stijn Wigerinck, Adriana V Gregory, Byron H Smith, Ioan-Andrei Iliuta, Christian Hanna, Maroun Chedid, Hasan-Daniel N Kaidbay, Sarah R Senum, Shebaz Shukoor, Peter C Harris, Vicente E Torres, Timothy L Kline, Fouad T Chebib
Publikováno v:
Clinical Kidney Journal.
Background and objectives Autosomal Dominant Polycystic Kidney Disease (ADPKD) presents with variable disease severity and progression. Advanced imaging biomarkers may provide insights into cystic and non-cystic processes leading to kidney failure in
Autor:
Aleksandar Denic, Aidan F. Mullan, Mariam P. Alexander, Luke D. Wilson, Joshua Augustine, Anthony C. Luehrs, Mark D. Stegall, Timothy L. Kline, Vidit Sharma, R. Houston Thompson, Andrew D. Rule
Publikováno v:
Journal of the American Society of Nephrology.