Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Timothy L. Jones"'
Autor:
Thomas R. Barrick, Catherine A. Spilling, Carson Ingo, Jeremy Madigan, Jeremy D. Isaacs, Philip Rich, Timothy L. Jones, Richard L. Magin, Matt G. Hall, Franklyn A. Howe
Publikováno v:
NeuroImage, Vol 211, Iss , Pp 116606- (2020)
To enable application of non-Gaussian diffusion magnetic resonance imaging (dMRI) techniques in large-scale clinical trials and facilitate translation to clinical practice there is a requirement for fast, high contrast, techniques that are sensitive
Externí odkaz:
https://doaj.org/article/4112b873f137457ba8d01506863f1eab
Publikováno v:
NeuroImage: Clinical, Vol 21, Iss , Pp - (2019)
Purpose: To develop a statistical method of combining multimodal MRI (mMRI) of adult glial brain tumours to generate tissue heterogeneity maps that indicate tumour grade and infiltration margins. Materials and methods: We performed a retrospective an
Externí odkaz:
https://doaj.org/article/e427ef863ee544d19561e1e999ce0f00
Autor:
Hildegard Dohmen, Hans-Georg Wirsching, Andreas von Deimling, Marco Stein, John G. Golfinos, Thomas Hielscher, Annika K. Wefers, Jens Schittenhelm, Fay E. A. Greenway, Areeba Patel, David T.W. Jones, Christian Mawrin, Chandra N. Sen, Elisabeth J. Rushing, Katrin Lamszus, Christine Jungk, Christina Blume, Anna S. Berghoff, Annekathrin Reinhardt, Jürgen Hench, Peter Baumgarten, Martin Sill, Till Acker, Daniel Schrimpf, Damian Stichel, Wolfgang Wick, David E. Reuss, Matija Snuderl, Miriam Ratliff, Marian Christoph Neidert, Michael Platten, Leslie R. Bridges, Sybren L. N. Maas, Abigail K. Suwala, Manfred Westphal, Stefan M. Pfister, Helin Dogan, Guido Reifenberger, Patrick N. Harter, Zane Jaunmuktane, Gerhard Jungwirth, Conor Grady, Severina Leu, Felix Sahm, Melanie Bewerunge-Hudler, Andreas Unterberg, Philipp Sievers, Nima Etminan, Michael Weller, Ralf Ketter, Jonathan Serrano, Matthias Preusser, Sebastian Brandner, Philipp Euskirchen, Christel Herold-Mende, Franz Ricklefs, Timothy L. Jones, Kenneth Aldape, Stephan Frank, Daniel Hänggi
Publikováno v:
Journal of Clinical Oncology. 39:3839-3852
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal impo
Autor:
Crescens Tiu, Wing Hing Yau, Liam C. Welsh, Timothy L. Jones, Anna Zachariou, Toby Prout, Mona Parmar, Alison J. Turner, Robert W. Daly, Christina Yap, Mateus Crespo, Bora Gurel, Ruth M. Riisnaes, Shaun A. DeCordova, Karen E. Swales, Udai Banerji, Anna R. Minchom, Adam Sharp, Johann S. de Bono, Juanita S. Lopez
Publikováno v:
Cancer Research. 83:CT093-CT093
Background PTEN loss of function is frequent in GBM correlating with poor prognosis, impaired antitumor responses and reduced efficacy of Immune Checkpoint Inhibitors (ICI). Ipat is a potent, selective, small-molecule inhibitor of Akt. Ipat efficient
Autor:
Timothy L Jones
Publikováno v:
BMJ. :o551
Autor:
Udai Banerji, Christina Yap, Crescens Diane Tiu, Juanita Lopez, Ruth Riisnaes, Rob Daly, Ben Jenkins, Mateus Crespo, Anna Minchom, J. De-Bono, Suzanne Carreira, Igor Vivanco, Liam Welsh, Alison Turner, Anna Zachariou, Toby Prout, Timothy L. Jones, Bora Gurel, Nina Tunariu
Publikováno v:
Neuro Oncol
Aims Despite improved understanding of effector T-cell trafficking into the central nervous system, initial trials with anti-PD1/PD-L1 immune checkpoint inhibitors (ICIs) have failed to meet their primary endpoints. PTEN loss of function is frequent
Autor:
Anna Minchom, Mateus Crespo, Johann S. de Bono, Toby Prout, Igor Vivanco, Crescens Tiu, Suzanne Carreira, Christina Yap, Liam Welsh, Ruth Riisnaes, Ben Jenkins, Alison Turner, Robert Daly, Juanita Lopez, Timothy L. Jones, Udai Banerji, Bora Gurel, Anna Zachariou, Andrea Biondo, Nina Tunariu
Publikováno v:
Cancer Research. 81:CT120-CT120
Background: Hyperactivation of the PI3K/AKT pathway correlates with impaired antitumour response, including reduced T cell infiltration into tumour and reduced efficacy of immune checkpoint inhibitors (ICIs). PTEN loss of function, often observed in
Publikováno v:
Poster Presentations.
Background: To ensure a timely diagnosis of RA, diagnostic US is increasingly being utilized to detect subclinical pathology in order to implement treatment plans rapidly. There are several ‘optimal’ synovitis scoring protocols in the literature
Autor:
Carson Ingo, Philip Rich, Jeremy D. Isaacs, Richard L. Magin, Catherine A. Spilling, Thomas R. Barrick, Timothy L. Jones, Matthew Hall, Franklyn A. Howe, Jeremy Madigan
Publikováno v:
NeuroImage, Vol 211, Iss, Pp 116606-(2020)
To enable application of non-Gaussian diffusion magnetic resonance imaging (dMRI) techniques in large-scale clinical trials and facilitate translation to clinical practice there is a requirement for fast, high contrast, techniques that are sensitive
Autor:
Jacob Chen Ming Low, Timothy L. Jones, Paul Johns, Philip Rich, Sean M. Barber, Bridget K MacDonald
Publikováno v:
World neurosurgery. 115
Background Calcifying pseudoneoplasm of the neuraxis (CAPNON) is a rare central nervous system lesion that can occur in both the brain and the spine. Although this entity is poorly understood, radiologic and histological features have been identified