Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Timothy L. Andersen"'
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Conventional de novo drug design is costly and time consuming, making it accessible to only the best resourced research organizations. An emergent approach to new drug development is drug repurposing, in which compounds that have
Externí odkaz:
https://doaj.org/article/45ba5aa17c5d41298f9ee12873d3c712
Autor:
Christopher Green, Elton Graugnard, Luca Piantanida, William L. Hughes, George D. Dickinson, Golam Md Mortuza, Timothy L. Andersen, Chad S. Watson, Reza M. Zadegan, William Clay, Eric J. Hayden, Wan Kuang
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
DNA is a compelling alternative to non-volatile information storage technologies due to its information density, stability, and energy efficiency. Previous studies have used artificially synthesized DNA to store data and automated next-generation seq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5306a89dbf77f8a7477ec6a1ecdfe7f4
https://pubmed.ncbi.nlm.nih.gov/33888693
https://pubmed.ncbi.nlm.nih.gov/33888693
Autor:
Thomas M. Green, Timothy L. Andersen
Publikováno v:
GECCO Companion
Understanding how the complex interactions of the problem-algorithm combination lead to an algorithm's search performance is arguably one of the most important open questions in metaheuristic algorithm theory. Examination of the fitness landscape doe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d27394ad51b04739562c91bef0d435d
https://doi.org/10.1145/3377929.3398140
https://doi.org/10.1145/3377929.3398140
Publikováno v:
IEEE Workshop on Microelectronics and Electron Devices : [proceedings]. IEEE Workshop on Microelectronics and Electron Devices. 2017
The global demand for digital data is projected to be greater than the supply of semiconductor grade silicon in 2040 [1]. When combined with the need to archive information [2], nucleic acids are being explored as an alternative memory material [1-7]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22016fdca04c2e3285b068198898bc8d
https://pubmed.ncbi.nlm.nih.gov/31543931
https://pubmed.ncbi.nlm.nih.gov/31543931
Publikováno v:
HICSS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6fd94115c87ff204f217330cb7a5ede
https://doi.org/10.24251/hicss.2019.936
https://doi.org/10.24251/hicss.2019.936
Publikováno v:
AIMS Molecular Science, Vol 3, Iss 2, Pp 238-245 (2016)
Due to low cost, speed, and unmatched ability to explore large numbers of compounds, high throughput virtual screening and molecular docking engines have become widely utilized by computational scientists. It is generally accepted that docking engine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309c206eac9477872f11c2680db90555
http://www.aimspress.com/Molecular/article/787/fulltext.html
http://www.aimspress.com/Molecular/article/787/fulltext.html
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
Background Conventional de novo drug design is costly and time consuming, making it accessible to only the best resourced research organizations. An emergent approach to new drug development is drug repurposing, in which compounds that have already g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56158cda88be1d02379e895fbbf1f830
http://europepmc.org/articles/PMC5902895
http://europepmc.org/articles/PMC5902895
Autor:
Sarah Bradburn, Owen M. McDougal, Timothy L. Andersen, Paul Daniel Phillips, Matthew W. Turner, Sarah Lew, Michael Katz, Matthew D. King
Publikováno v:
Biochemistry and Molecular Biology Education. 44:63-67
Computational molecular docking is a fast and effective in silico method for the analysis of binding between a protein receptor model and a ligand. The visualization and manipulation of protein to ligand binding in three-dimensional space represents
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5297320b6a7b59e0b377398a7d03cdb2
https://doi.org/10.1002/bmb.20925
https://doi.org/10.1002/bmb.20925
Publikováno v:
Journal of Computational Chemistry. 36:1304-1310
The prominence of endogenous peptide ligands targeted to receptors makes peptides with the desired binding activity good molecular scaffolds for drug development. Minor modifications to a peptide's primary sequence can significantly alter its binding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19369370f46c4ff4f13472fe6f4cbf6e
https://doi.org/10.1002/jcc.23928
https://doi.org/10.1002/jcc.23928
Publikováno v:
2017 Intelligent Systems Conference (IntelliSys).
In this paper we propose a stacking approach for Convolutional Neural Network (CNN) transfer learning ensemble for remote sensing imagery, in particular for the task of scene classification. We propose to use a combination of features produced by an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45ee7d5fbd75fff5a972d8a7ee2c60c
https://doi.org/10.1109/intellisys.2017.8324356
https://doi.org/10.1109/intellisys.2017.8324356