Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Timothy L Denning"'
Autor:
Jörn-Hendrik Weitkamp, Michael J Rosen, Zhiguo Zhao, Tatsuki Koyama, Duke Geem, Timothy L Denning, Michael T Rock, Daniel J Moore, Melissa D Halpern, Pranathi Matta, Patricia W Denning
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99042 (2014)
Gastrointestinal barrier immaturity predisposes preterm infants to necrotizing enterocolitis (NEC). Intraepithelial lymphocytes (IEL) bearing the unconventional T cell receptor (TCR) γδ (γδ IEL) maintain intestinal integrity and prevent bacterial
Externí odkaz:
https://doaj.org/article/7fa6390931d6430696479415c3c4bb58
Autor:
Julie Mirpuri, Ilya Sotnikov, Loren Myers, Timothy L Denning, Felix Yarovinsky, Charles A Parkos, Patricia W Denning, Nancy A Louis
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51955 (2012)
The intestinal microflora is critical for normal development, with aberrant colonization increasing the risk for necrotizing enterocolitis (NEC). In contrast, probiotic bacteria have been shown to decrease its incidence. Multiple pro- and anti-inflam
Externí odkaz:
https://doaj.org/article/543af17def9249fba91aa0c55bbad3e9
Publikováno v:
Frontiers in Microbiology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/38563016ee1647aab7b9c47bcae73ad0
Autor:
Hirohito Abo, Aoi Muraki, Akihito Harusato, Tetsuya Imura, Maki Suzuki, Kohta Takahashi, Timothy L. Denning, Hiroto Kawashima
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
Intestinal mucins play an essential role in the defense against bacterial invasion and the maintenance of gut microbiota, which is instrumental in the regulation of host immune systems; hence, its dysregulation is a hallmark of metabolic disease and
Externí odkaz:
https://doaj.org/article/1766862cd9df4b9ab9ae3c9abe3501b9
Publikováno v:
ACS Omega, Vol 5, Iss 36, Pp 23118-23128 (2020)
Externí odkaz:
https://doaj.org/article/b67a17b28eca4bc9a041979424534a49
Autor:
Mingcan Yu, Abdul Malik Tyagi, Jau-Yi Li, Jonathan Adams, Timothy L. Denning, M. Neale Weitzmann, Rheinallt M. Jones, Roberto Pacifici
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
T cells are involved in the bone loss induced by parathyroid hormone (PTH), but their origin is unknown. Here, the authors show that the intestinal microbiota is required for PTH to induce bone loss and describes mechanisms for microbiota-mediated gu
Externí odkaz:
https://doaj.org/article/3f73e1cc8c504ed8ad4787bd0c1d7608
Autor:
Hirohito Abo, Benoit Chassaing, Akihito Harusato, Miguel Quiros, Jennifer C. Brazil, Vu L. Ngo, Emilie Viennois, Didier Merlin, Andrew T. Gewirtz, Asma Nusrat, Timothy L. Denning
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Gut microbiota and their metabolites regulate homeostasis of the intestine, but their effects on intestine development are unclear. Here the authors use RNAseq and germ free mice to show that intestinal microbiota promote the expression of Erdr1, whi
Externí odkaz:
https://doaj.org/article/041717f946814996be968b7a702f6fb1
Publikováno v:
bioRxiv
Inflammatory bowel disease (IBD) is a multifactorial, chronic disease that affects approximately 1.5 million people in the United States [1]. It presents with inflammation of the intestine with unknown etiology and its two main forms are Crohn’s di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bbcc5daf555e76784a06e47bf24bafa
https://europepmc.org/articles/PMC10245963/
https://europepmc.org/articles/PMC10245963/
Autor:
Timothy L. Denning, Andrew T. Gewirtz, Didier Merlin, Jian-Dong Li, Yoshito Itoh, Yuji Naito, Nicholas W. Lukacs, Satoru Osuka, Hirohito Abo, Shingo Matsuyama, Lucie Etienne-Mesmin, Emilie Viennois, Akihito Harusato
Gut microbiota and their metabolites are instrumental in regulating homeostasis at intestinal and extraintestinal sites. However, the complex effects of prenatal and early postnatal microbial exposure on adult health and disease outcomes remain incom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841dcc635f0d276412f3147f6a8f50ec
https://doi.org/10.1158/2326-6066.c.6549089.v1
https://doi.org/10.1158/2326-6066.c.6549089.v1
Autor:
Timothy L. Denning, Andrew T. Gewirtz, Didier Merlin, Jian-Dong Li, Yoshito Itoh, Yuji Naito, Nicholas W. Lukacs, Satoru Osuka, Hirohito Abo, Shingo Matsuyama, Lucie Etienne-Mesmin, Emilie Viennois, Akihito Harusato
Complete Supplementary Data File
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a24dcdadd4115196d490cddc336ac8
https://doi.org/10.1158/2326-6066.22539416.v1
https://doi.org/10.1158/2326-6066.22539416.v1