Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Timothy L Chen"'
Autor:
Erin Hertlein, Kyle A Beckwith, Gerard Lozanski, Timothy L Chen, William H Towns, Amy J Johnson, Amy Lehman, Amy S Ruppert, Brad Bolon, Leslie Andritsos, Arletta Lozanski, Laura Rassenti, Weiqiang Zhao, Tiina M Jarvinen, Leigha Senter, Carlo M Croce, David E Symer, Albert de la Chapelle, Nyla A Heerema, John C Byrd
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76607 (2013)
Studies of chronic lymphocytic leukemia (CLL) have yielded substantial progress, however a lack of immortalized cell lines representative of the primary disease has hampered a full understanding of disease pathogenesis and development of new treatmen
Externí odkaz:
https://doaj.org/article/6701b5761778490aa7e468949244dd8d
Autor:
Gunvant R. Chaudhari, Yeshwant R. Chillakuru, Timothy L. Chen, Valentina Pedoia, Thienkhai H. Vu, Christopher P. Hess, Youngho Seo, Jae Ho Sohn
Publikováno v:
BMC Medical Imaging, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background The comprehensiveness and maintenance of the American College of Radiology (ACR) Appropriateness Criteria (AC) makes it a unique resource for evidence-based clinical imaging decision support, but it is underutilized by clinicians.
Externí odkaz:
https://doaj.org/article/046f093aa07f41fc9a6de5b78a678369
Autor:
Yeshwant Reddy Chillakuru, Shourya Munjal, Benjamin Laguna, Timothy L. Chen, Gunvant R. Chaudhari, Thienkhai Vu, Youngho Seo, Jared Narvid, Jae Ho Sohn
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background A systematic approach to MRI protocol assignment is essential for the efficient delivery of safe patient care. Advances in natural language processing (NLP) allow for the development of accurate automated protocol assignment. We a
Externí odkaz:
https://doaj.org/article/f0657fccdd3747b78beddbed5ad57d3a
Autor:
Timothy L. Chen, Bonnie Harrington, Jean Truxall, Ronni Wasmuth, Alexander Prouty, Shelby Sloan, Amy M. Lehman, Deepa Sampath, Eric Orlemans, Robert A. Baiocchi, Lapo Alinari, John C. Byrd, Jennifer A. Woyach, Erin Hertlein
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-5 (2021)
Abstract B-cell receptor (BCR) antagonists such as the BTK inhibitor ibrutinib have proven to effectively target chronic lymphocytic leukemia (CLL) tumor cells, leading to impressive response rates in these patients. However patients do still relapse
Externí odkaz:
https://doaj.org/article/4c01d238e7a84a94ba1ec2e43998f4b6
Autor:
David M. Lucas, John C. Byrd, David Jarjoura, Amy Lehman, Jennifer A. Woyach, Melanie E. Davis, Timothy L. Chen, Rosa Lapalombella, Ellen J. Sass, Yanhui Lu, Erin Hertlein, Sneha V. Gupta
PDF file - 82K, Supplementary Table 1: Fold changes of NF-κB target genes in CLL: CLL cells (n=12) were treated with 300 nM CFZ (1 hr), 1.7 �M CpG (4 hr) or 500 ng/ml CD40L (4 hr). RNA was extracted at 8 hr from CFZ treated samples and mRNA expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::429495449090b520dfc6671cc4ea61d9
https://doi.org/10.1158/1078-0432.22449231
https://doi.org/10.1158/1078-0432.22449231
Autor:
David M. Lucas, John C. Byrd, David Jarjoura, Amy Lehman, Jennifer A. Woyach, Melanie E. Davis, Timothy L. Chen, Rosa Lapalombella, Ellen J. Sass, Yanhui Lu, Erin Hertlein, Sneha V. Gupta
Purpose: The proteasome consists of chymotrypsin-like (CT-L), trypsin-like, and caspase-like subunits that cleave substrates preferentially by amino acid sequence. Proteasomes mediate degradation of regulatory proteins of the p53, Bcl-2, and nuclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4165083994892e957d76197c34858d64
https://doi.org/10.1158/1078-0432.c.6521586.v1
https://doi.org/10.1158/1078-0432.c.6521586.v1
Autor:
David M. Lucas, John C. Byrd, David Jarjoura, Amy Lehman, Jennifer A. Woyach, Melanie E. Davis, Timothy L. Chen, Rosa Lapalombella, Ellen J. Sass, Yanhui Lu, Erin Hertlein, Sneha V. Gupta
PDF file - 183K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c00f7dd78539aa76d3e162cd185bdef
https://doi.org/10.1158/1078-0432.22449234
https://doi.org/10.1158/1078-0432.22449234
Autor:
Benjamin Laguna, Youngho Seo, Thienkhai Vu, Shourya Munjal, Jae Ho Sohn, Gunvant R. Chaudhari, Jared Narvid, Timothy L. Chen, Yeshwant Chillakuru
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-10 (2021)
BMC medical informatics and decision making, vol 21, iss 1
BMC Medical Informatics and Decision Making
BMC medical informatics and decision making, vol 21, iss 1
BMC Medical Informatics and Decision Making
Background A systematic approach to MRI protocol assignment is essential for the efficient delivery of safe patient care. Advances in natural language processing (NLP) allow for the development of accurate automated protocol assignment. We aim to dev
Autor:
Gunvant R. Chaudhari, Tengxiao Liu, Timothy L. Chen, Gabby B. Joseph, Maya Vella, Yoo Jin Lee, Thienkhai H. Vu, Youngho Seo, Andreas M. Rauschecker, Charles E. McCulloch, Jae Ho Sohn
Publikováno v:
Radiology. Artificial intelligence, vol 4, iss 4
Radiol Artif Intell
Radiol Artif Intell
PURPOSE: To develop radiology domain–specific bidirectional encoder representations from transformers (BERT) models that can identify speech recognition (SR) errors and suggest corrections in radiology reports. MATERIALS AND METHODS: A pretrained B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f35b657fdab8d3bb0864f694b70114
https://escholarship.org/uc/item/86k0t1xf
https://escholarship.org/uc/item/86k0t1xf
Autor:
Jordan Chervin, Ross L. Levine, Tara L. Lin, Ying Huang, William Blum, Sonja Marcus, Tibor Kovacsovics, Ashley O. Yocum, Franchesca Druggan, Gary J. Schiller, Brian J. Druker, Mona Stefanos, Uma Borate, Matthew C. Foster, Mark R. Litzow, John C. Byrd, Nyla A. Heerema, Robert H. Collins, Abigail B. Shoben, Wendy Stock, Leonard Rosenberg, Amy Burd, Michael Boyiadzis, James M. Foran, Rebecca L. Olin, Jo-Anne Vergilio, Prapti A. Patel, Maria R. Baer, Timothy L. Chen, Eytan M. Stein, Alice S. Mims
Publikováno v:
Blood. 136:27-30
Background: ENA is an oral, selective inhibitor of IDH2 approved for the treatment (Tx) of patients (pts) with relapsed/refractory IDH2 mutated (IDH2m) AML. Here we report the results of a Phase 2 expansion and Phase 1b of the Beat AML Master Trial P