Zobrazeno 1 - 10
of 519
pro vyhledávání: '"Timothy L, Ratliff"'
Autor:
Paula O. Cooper, Jiang Yang, Hsing-Hui Wang, Meaghan M. Broman, Shyaman Madhawa Jayasundara, Subhransu Sekhar Sahoo, Bingyu Yan, Gada D. Awdalkreem, Gregory M. Cresswell, Liang Wang, Emery Goossens, Nadia A. Lanman, Rebecca W. Doerge, Faye Zheng, Liang Cheng, Saeed Alqahtani, Scott A. Crist, Robert E. Braun, Majid Kazemian, Travis J. Jerde, Timothy L. Ratliff
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Chronic prostate inflammation in patients with benign prostate hyperplasia (BPH) correlates with the severity of symptoms. How inflammation contributes to prostate enlargement and/or BPH symptoms and the underlying mechanisms remain unclear.
Externí odkaz:
https://doaj.org/article/be19327c8fd048d4a027b078790de3fc
Autor:
Fenghua Zhang, Bo Huang, Sagar M. Utturkar, Weichuan Luo, Gregory Cresswell, Seth A. Herr, Suilan Zheng, John V. Napoleon, Rina Jiang, Boning Zhang, Muyi Liu, Nadia Lanman, Madduri Srinivasarao, Timothy L. Ratliff, Philip S. Low
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Folate receptors can perform folate transport, cell adhesion, and/or transcription factor functions. The beta isoform of the folate receptor (FRβ) has attracted considerable attention as a biomarker for immunosuppressive macrophages and myeloid-deri
Externí odkaz:
https://doaj.org/article/6dc8dbece4744d66b4109cdad3fb1700
Autor:
Renee E. Vickman, LaTayia Aaron-Brooks, Renyuan Zhang, Nadia A. Lanman, Brittany Lapin, Victoria Gil, Max Greenberg, Takeshi Sasaki, Gregory M. Cresswell, Meaghan M. Broman, J. Sebastian Paez, Jacqueline Petkewicz, Pooja Talaty, Brian T. Helfand, Alexander P. Glaser, Chi-Hsiung Wang, Omar E. Franco, Timothy L. Ratliff, Kent L. Nastiuk, Susan E. Crawford, Simon W. Hayward
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Reduction of systemic autoimmunity using TNF blockers may also reduce inflammatory diseases in other organs. Here, the authors use a patient database and scRNA-seq to link autoimmune diseases to benign prostatic hyperplasia (BPH), and demonstrate tha
Externí odkaz:
https://doaj.org/article/572e6df1a2f4471bb53b3a820ff54a37
Autor:
Ryan D. Calvert, James C. Fleet, Pierrick G. J. Fournier, Patricia Juarez, Grant N. Burcham, Jessica M. Haverkamp, Theresa A. Guise, Timothy L. Ratliff, Bennett D. Elzey
Publikováno v:
ImmunoHorizons. 6:790-806
Owing to ease of access and high yield, most murine myeloid-derived suppressor cell (MDSC) knowledge comes from the study of spleen-derived MDSCs rather than those isolated from the tumor. Although several studies have identified subtle differences i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f5e6315396ae3cf7bd279caeced46ce
https://doi.org/10.4049/immunohorizons.2200079
https://doi.org/10.4049/immunohorizons.2200079
Autor:
Hao Chen, Gregory M. Cresswell, Sarah Libring, Mitchell G. Ayers, Jinmin Miao, Zhong-Yin Zhang, Luis Solorio, Timothy L. Ratliff, Michael K. Wendt
Publikováno v:
Cancer Research Communications. 2:1104-1118
SH2 containing protein tyrosine phosphatase-2 (SHP2) is recognized as a druggable oncogenic phosphatase that is expressed in both tumor cells and immune cells. How tumor cell–autonomous SHP2 contributes to an immunosuppressive tumor microenvironmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e143b1dfa4a43e522fbfe10ea775d7e5
https://doi.org/10.1158/2767-9764.crc-22-0117
https://doi.org/10.1158/2767-9764.crc-22-0117
Autor:
Deborah W. Knapp, Deepika Dhawan, José A. Ramos-Vara, Timothy L. Ratliff, Gregory M. Cresswell, Sagar Utturkar, Breann C. Sommer, Christopher M. Fulkerson, Noah M. Hahn
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
There is a great need to improve the outlook for people facing urinary bladder cancer, especially for patients with invasive urothelial carcinoma (InvUC) which is lethal in 50% of cases. Improved outcomes for patients with InvUC could come from advan
Externí odkaz:
https://doaj.org/article/0206712675914fc8827da681833cf6e6
Autor:
Feng Yue, Pengpeng Bi, Chao Wang, Tizhong Shan, Yaohui Nie, Timothy L. Ratliff, Timothy P. Gavin, Shihuan Kuang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Pten is known to regulate haematopoietic stem cell functions. Here the authors show that Ptenalteration of Notch signalling has stage-specific muscle regenerative functions in muscle stem cells by preventing premature differentiation of quiescent cel
Externí odkaz:
https://doaj.org/article/00969596d127462ca70e44a0269cbe23
Autor:
Jake L. Owens, Elena Beketova, Sheng Liu, Qi Shen, Jogendra Singh Pawar, Andrew M. Asberry, Jie Yang, Xuehong Deng, Bennett D. Elzey, Timothy L. Ratliff, Liang Cheng, Richard Choo, Deborah E. Citrin, Thomas J. Polascik, Bangchen Wang, Jiaoti Huang, Chenglong Li, Jun Wan, Chang-Deng Hu
Publikováno v:
Molecular Cancer Therapeutics. 21:448-459
Prostate cancer remains the second leading cause of cancer death among American men. Radiotherapy is a potentially curative treatment for localized prostate cancer, and failure to control localized disease contributes to the majority of prostate canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f2e9f43c1c46ca9bba0837ea994551
https://doi.org/10.1158/1535-7163.mct-21-0103
https://doi.org/10.1158/1535-7163.mct-21-0103
Autor:
Michael K. Wendt, Timothy L. Ratliff, Luis Solorio, Zhong-Yin Zhang, Jinmin Miao, Mitchell G. Ayers, Sarah Libring, Gregory M. Cresswell, Hao Chen
This is the code information for publicly available data analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a579f39c9e7095867fdc8ebafad3eb8
https://doi.org/10.1158/2767-9764.22545114
https://doi.org/10.1158/2767-9764.22545114
Autor:
Michael K. Wendt, Timothy L. Ratliff, Luis Solorio, Zhong-Yin Zhang, Jinmin Miao, Mitchell G. Ayers, Sarah Libring, Gregory M. Cresswell, Hao Chen
Corresponding representative dot plots for the quantification in figure 2D-F and additional myeloid composition analysis in the study of D2.A1 model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89a24fc952f31338e9d012df4eb3e043
https://doi.org/10.1158/2767-9764.22545129.v1
https://doi.org/10.1158/2767-9764.22545129.v1