Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Timothy K, Lee"'
Autor:
Yideng Liang, Joseph W. Jackson, Samuel A. Woodle, Stepan S. Surov, Leonid A. Parunov, Dorothy E. Scott, Mark Weinstein, Timothy K. Lee, Mikhail V. Ovanesov
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 1, Pp 211-222 (2021)
Abstract Background Activated coagulation factor XIa (FXIa) is an impurity and primary source of procoagulant activity in thrombosis‐implicated immune globulin (IG) products. Several assays, of varying quality and precision are used to assess FXIa
Externí odkaz:
https://doaj.org/article/ab2eec995bec476b91c3b022656c3222
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
The bacterial cell wall is important for cell shape and stability, but how the activities of the biosynthetic machinery are coordinated are not clear. Here the authors use single-molecule imaging and chemical perturbations to determine factors that a
Externí odkaz:
https://doaj.org/article/f7a4d8ae5c9b480e83c2b8ff44dde880
Autor:
Claire S. Koechlein, Jeffrey R. Harris, Timothy K. Lee, Joi Weeks, Raymond G. Fox, Bryan Zimdahl, Takahiro Ito, Allen Blevins, Seung-Hye Jung, John P. Chute, Amit Chourasia, Markus W. Covert, Tannishtha Reya
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
It is difficult to image haematopoietic stem cells (HSC) in their niche. Here, the authors present a new high-throughput computational approach to visualise HSCs in vivoat a high spatial and temporal resolution and also use a Msi2-reporter to label e
Externí odkaz:
https://doaj.org/article/eb98c9dbcd7d47d28ac28ab4c7bfb28b
Autor:
Mary Beth Madonna, Srikumar Pillai, Timothy K. Lee, Nicholas J. Skertich, Ami N. Shah, Miles W. Grunvald, Rona M. Tiglao, Adithya Sivakumar
Publikováno v:
Journal of Pediatric Surgery. 57:418-423
Gastrostomy tube (GT) placement is a common pediatric procedure with high postoperative resource utilization. We aimed to determine if standardized discharge instructions (SDI) reduced healthcare utilization rates.We performed a retrospective cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::076f077f0c356d003b3b522b8e1ed7b0
https://doi.org/10.1016/j.jpedsurg.2021.03.045
https://doi.org/10.1016/j.jpedsurg.2021.03.045
Autor:
Xiao Jia, Eugene Shkolyar, Okyaz Eminaga, Mark Laurie, Zixia Zhou, Timothy K. Lee, Md Tauhidul Islam, Max Q.-H. Meng, Joseph C. Liao, Lei Xing
Publikováno v:
Advanced Photonics in Urology 2023.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e734d10ed48ce0ccc26a315030f153
https://doi.org/10.1117/12.2650583
https://doi.org/10.1117/12.2650583
Publikováno v:
Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XXI.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d81405b6a86742e3bd6fdb6ce62c3a6
https://doi.org/10.1117/12.2650920
https://doi.org/10.1117/12.2650920
Autor:
Leonid A Parunov, Yideng Liang, Qijin Lu, Alexey M Shibeko, Erik I. Tucker, Timothy K. Lee, Fazoil I Ataullakhanov, Dorothy Scott, Mikhail V Ovanesov
Publikováno v:
Blood Advances.
Inhibitors of coagulation factor (F) XIa are currently investigated as potential anticoagulant therapies. We hypothesized that circulating FXIa may be a potential target for these therapies. Using previous analyses of FXIa impurity in immune globulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25761cdb087100a2c10a3455f6660c82
https://doi.org/10.1182/bloodadvances.2022008743
https://doi.org/10.1182/bloodadvances.2022008743
Publikováno v:
Journal of Thrombosis and Haemostasis. 19:2102-2111
New modified coagulation factor VIII (FVIII) and factor IX (FIX) products have been designed to improve the treatment of individuals with hemophilia A and B by increasing the interval between dosing. Although these FVIII and FIX molecules have been s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6204542c6fb598ea4b3bddf828db13c
https://doi.org/10.1111/jth.15425
https://doi.org/10.1111/jth.15425
Autor:
Yideng Liang, Leonid A. Parunov, Maria E Shea, Mikhail V Ovanesov, Stepan S Surov, Dorothy E. Scott, Timothy K Lee, Maitreyi Chattopadhyay
Publikováno v:
Nature Protocols. 16:3981-4003
Thrombin generation (TG) assays are used widely to investigate both diseases and drugs that impact thrombosis and bleeding. TG assays were also instrumental in the identification of thrombogenic impurities in immune globulin products, which were asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e943a833a9c492c283998a62fce4f47
https://doi.org/10.1038/s41596-021-00568-4
https://doi.org/10.1038/s41596-021-00568-4
Autor:
Carolina Tropini, Timothy K. Lee, Jen Hsin, Samantha M. Desmarais, Tristan Ursell, Russell D. Monds, Kerwyn Casey Huang
Publikováno v:
Cell Reports, Vol 9, Iss 4, Pp 1520-1527 (2014)
Although bacterial cell morphology is tightly controlled, the principles of size regulation remain elusive. In Escherichia coli, perturbation of cell-wall synthesis often results in similar morphologies, making it difficult to deconvolve the complex
Externí odkaz:
https://doaj.org/article/737239ade19e4cc7a48311c99d391b75