Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Timothy K, Cooper"'
Autor:
Winston T. Chu, Marcelo A. Castro, Syed Reza, Timothy K. Cooper, Sean Bartlinski, Dara Bradley, Scott M. Anthony, Gabriella Worwa, Courtney L. Finch, Jens H. Kuhn, Ian Crozier, Jeffrey Solomon
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Detection of the physiological response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is challenging in the absence of overt clinical signs but remains necessary to understand a full subclinical disease spectrum.
Externí odkaz:
https://doaj.org/article/6f41bfc0a7674915be944af6f67292ac
Autor:
Gabriella Worwa, Timothy K. Cooper, Steven Yeh, Jessica G. Shantha, Amanda M. W. Hischak, Sarah E. Klim, Russell Byrum, Jonathan R. Kurtz, Scott M. Anthony, Nina M. Aiosa, Danny Ragland, Ji Hyun Lee, Marisa St. Claire, Carl Davis, Rafi Ahmed, Michael R. Holbrook, Jens H. Kuhn, Erica Ollmann Saphire, Ian Crozier
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-10 (2022)
Deep characterization of uveitis in a rhesus monkey confirms Ebola virus RNA persistence is associated with severe immunopathology in the eye, with broader implications for the prevention and treatment of sight-threatening uveitis in human survivors
Externí odkaz:
https://doaj.org/article/7a1f01ecfa0544e299e0f3738ed8d6f3
Autor:
Nancy M. Cladel, Pengfei Jiang, Jingwei J. Li, Xuwen Peng, Timothy K. Cooper, Vladimir Majerciak, Karla K. Balogh, Thomas J. Meyer, Sarah A. Brendle, Lynn R. Budgeon, Debra A. Shearer, Regina Munden, Maggie Cam, Raghavan Vallur, Neil D. Christensen, Zhi-Ming Zheng, Jiafen Hu
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 1108-1121 (2019)
ABSTRACTHuman papillomaviruses (HPV) contribute to most cervical cancers and are considered to be sexually transmitted. However, papillomaviruses are often found in cancers of internal organs, including the stomach, raising the question as to how the
Externí odkaz:
https://doaj.org/article/14b4fcbaf652421bacab4a29543817a2
Autor:
Timothy K. Cooper, Louis Huzella, Joshua C. Johnson, Oscar Rojas, Sri Yellayi, Mei G. Sun, Sina Bavari, Amanda Bonilla, Randy Hart, Peter B. Jahrling, Jens H. Kuhn, Xiankun Zeng
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Survivors of Ebola virus infection may become subclinically infected, but whether animal models recapitulate this complication is unclear. Using histology in combination with immunohistochemistry and in situ hybridization in a retrospective
Externí odkaz:
https://doaj.org/article/948a329586ed44359c28050be99073b3
Autor:
Reed F. Johnson, Lauren A. Keith, Timothy K. Cooper, Srikanth Yellayi, Nicole M. Josleyn, Krisztina B. Janosko, James D. Pettitt, David Thomasson, Katie R. Hagen, Robin Gross, John G. Bernbaum, Debbie Douglas, Jeffrey Solomon, Mark Martinez, Kurt Cooper, Marisa St. Claire, Danny R. Ragland, Peter B. Jahrling, Jens H. Kuhn, Andrew E. Arai
Publikováno v:
Viruses, Vol 13, Iss 8, p 1571 (2021)
Hemorrhagic smallpox, caused by variola virus (VARV), was a rare but nearly 100% lethal human disease manifestation. Hemorrhagic smallpox is frequently characterized by secondary bacterial infection, coagulopathy, and myocardial and subendocardial he
Externí odkaz:
https://doaj.org/article/529da320d14a4600a4622666dfa585c4
Autor:
Nancy M. Cladel, Lynn R. Budgeon, Karla K. Balogh, Timothy K. Cooper, Sarah A. Brendle, Neil D. Christensen, Todd D. Schell, Jiafen Hu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mouse papillomavirus has shown broad tissue tropism in nude mice. Previous studies have tested cutaneous infections in different immunocompromised and immunocompetent mouse strains. In the current study, we examined mucosal infection in seve
Externí odkaz:
https://doaj.org/article/df8831acce684d48b751234e509a3a56
Autor:
Kristin K. Fino, Linlin Yang, Patricia Silveyra, Sanmei Hu, Todd M. Umstead, Susan DiAngelo, E. Scott Halstead, Timothy K. Cooper, Thomas Abraham, Yoshinori Takahashi, Zhixiang Zhou, Hong Gang Wang, Zissis C. Chroneos
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract New influenza A viruses that emerge frequently elicit composite inflammatory responses to both infection and structural damage of alveolar-capillary barrier cells that hinders regeneration of respiratory function. The host factors that relin
Externí odkaz:
https://doaj.org/article/9f2db467b2f24fcdb539803d205c307c
PDF file - 259K, Supplementary Figure 1. CD8+ T cell accumulation in the TRAMP prostate is tumor antigen-dependent. Supplementary Figure 2. Widespread disease regression in 2X WBI + TCR-IV treated mice. Supplementary Figure 3. Recovery from radiation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d9abc4ca395d9dbdab4534d19dd9238
https://doi.org/10.1158/2326-6066.22537946
https://doi.org/10.1158/2326-6066.22537946
Adoptive immunotherapy has demonstrated efficacy in a subset of clinical and preclinical studies, but the T cells used for therapy often are rendered rapidly nonfunctional in tumor-bearing hosts. Recent evidence indicates that prostate cancer can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f43971c8ab77eb3887872dc78b5c632f
https://doi.org/10.1158/2326-6066.c.6548618.v1
https://doi.org/10.1158/2326-6066.c.6548618.v1
Autor:
David X. Liu, Peter B. Jahrling, Russell Byrum, Danny Ragland, Donna L. Perry, Nejra Isic, Timothy K. Cooper, Louis Huzella, Rebecca J. Reeder, Kurt Cooper, Michael R. Holbrook, James Logue, Richard S. Bennett, Marisa St. Claire, Lisa E. Hensley, Randy Hart, Amanda M.W. Hischak
Publikováno v:
The American Journal of Pathology. 192:121-129
The pathogenesis of Ebola virus disease (EVD) is still incomplete, although the non-human primate model has been studied for more than 4 decades. To further investigate EVD pathogenesis, a natural history study has been conducted using 27 Chinese-ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e3f4427c636123c80be2f8c9801d5fa
https://doi.org/10.1016/j.ajpath.2021.09.009
https://doi.org/10.1016/j.ajpath.2021.09.009