Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Timothy J. Toner"'
Autor:
Miguel Aste-Amézaga, Ningyan Zhang, Janet E Lineberger, Beth A Arnold, Timothy J Toner, Mingcheng Gu, Lingyi Huang, Salvatore Vitelli, Kim T Vo, Peter Haytko, Jing Zhang Zhao, Frederic Baleydier, Sarah L'Heureux, Hongfang Wang, Wendy R Gordon, Elizabeth Thoryk, Marie Blanke Andrawes, Kittichoat Tiyanont, Kimberly Stegmaier, Giovanni Roti, Kenneth N Ross, Laura L Franlin, Hui Wang, Fubao Wang, Michael Chastain, Andrew J Bett, Laurent P Audoly, Jon C Aster, Stephen C Blacklow, Hans E Huber
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9094 (2010)
Notch receptors normally play a key role in guiding a variety of cell fate decisions during development and differentiation of metazoan organisms. On the other hand, dysregulation of Notch1 signaling is associated with many different types of cancer
Externí odkaz:
https://doaj.org/article/b4ac98e727c04ff3ad08212b68b47d08
Development and evaluation of live influenza (LIV) cold-adapted reassortant vaccines in cell culture
Autor:
Rima Youil, Nikolai Kraiouchkine, Qin Su, Rudenko Lg, Timothy J. Toner, Irina Kiseleva, C. Szymkowiak, W.-S. Kwan, Alan Shaw
Publikováno v:
International Congress Series. 1263:551-554
The Russian influenza A live virus vaccine (LIV) is based on the temperature sensitive (ts) and cold-adapted (ca) A/Leningrad/134/17/57 (H2N2) donor strain (Len/17). Reassortants between current circulating A strains and the ca donor strain are tradi
Autor:
A. Klimov, Rudenko Lg, W.-S. Kwan, Alan Shaw, C. Szymkowiak, Timothy J. Toner, Qin Su, Rima Youil, Irina Kiseleva
Publikováno v:
International Congress Series. 1263:547-550
The main focus of this study was to explore the role of the gene segments of the cold-adapted (ca) A/Leningrad/134/17/57 (Len/17) influenza virus in the context of heterologous wild-type (wt) viruses. In this study, 34 MDCK-derived reassortants betwe
Autor:
W.-S. Kwan, Alan Shaw, Alexander Klimov, Rima Youil, Qin Su, Timothy J. Toner, C. Szymkowiak, Irina Kiseleva, Rudenko Lg
Publikováno v:
Virus Research. 102:165-176
For the past three decades the cold-adapted (ca) and temperature sensitive (ts) master donor strain, A/Leningrad/134/17/57 (H2N2) has been successfully used as the basis for the live attenuated reassortant influenza A vaccine. This donor strain was d
Autor:
Sarah L'Heureux, Ningyan Zhang, Janet Lineberger, Kittichoat Tiyanont, Hui Wang, Fubao Wang, Wendy R. Gordon, Jon C. Aster, Hans E. Huber, Lingyi Huang, Salvatore Vitelli, Laurent P. Audoly, Kenneth N. Ross, Kim Vo, Elizabeth Thoryk, Miguel Aste-Amezaga, Stephen C. Blacklow, Timothy J. Toner, Peter Haytko, Beth A. Arnold, Marie Blanke Andrawes, Kimberly Stegmaier, Jing Zhang Zhao, Mingcheng Gu, Michael Chastain, Hongfang Wang, Giovanni Roti, Frederic Baleydier, Laura L. Franlin, Andrew J. Bett
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9094 (2010)
PLoS ONE
PLoS ONE
Background Notch receptors normally play a key role in guiding a variety of cell fate decisions during development and differentiation of metazoan organisms. On the other hand, dysregulation of Notch1 signaling is associated with many different types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d172778b2828cb3442ce709acb47a69
http://hdl.handle.net/11391/1215082
http://hdl.handle.net/11391/1215082
Autor:
Rima Youil, Joan Wlochowski, Qin Su, Timothy J. Toner, Kimberly Johnston, Nikolai Kraiouchkine, Alan Shaw, Luba Petrukhin, Juanita Monteiro, Daniel J. DiStefano, Boris Rubin, Thomas J. Palker, W.-S. Kwan, Larisa Rudenko, Irina Kiseleva, C. Szymkowiak
Publikováno v:
Virus research. 105(2)
Live, cold-adapted, temperature-sensitive (ca/ts) Russian influenza A vaccines are prepared in eggs by a 6:2 gene reassortment of the ca/ts donor strain A/Leningrad/134/17/57 (H2N2) (Len/17) with a current wild-type (wt) influenza A strain contributi
Autor:
Timothy J. Toner, Rima Youil, C. Szymkowiak, Petrukhin L, Rubin B, Daniel J. DiStefano, Qin Su, Alan Shaw, Irina Kiseleva, W.-S. Kwan
Publikováno v:
Journal of virological methods. 120(1)
The choice of a cell line for the production of influenza vaccines is determined by how well the virus is able to replicate and how easily the cell line can be maintained. Madin-Darby canine kidney (MDCK) cells have long been known to successfully su
Autor:
Bethany M. Rogers, Michelle Chen, Danilo R. Casimiro, John W. Shiver, Ling Chen, Aimin Tang, Qin Su, Emilio A. Emini, Timothy J. Toner, Eric C. Burden, Andrew J. Bett, John G. Aunins, Rima Youil, David C. Kaslow, Nedim Emil Altaras
Publikováno v:
Human gene therapy. 14(10)
First-generation adenovectors have been developed for gene therapy and vaccine applications. The construction of these adenovectors has entailed the use of numerous types of expression cassettes. It has long been known that first-generation adenovect
Autor:
De-Min Zhu, Danilo R. Casimiro, John W. Shiver, Sheri Dubey, Donna M. Williams, Zheng Xu, Virginia Harris, Wendy L. Trigona, Lynne Isopi, Gwendolyn J. Heidecker, Jeffrey G. Smith, Qin Su, Minchun Chen, Timothy J. Toner, Lingyi Huang, Robert D. Troutman, Aimin Tang, Andrew J. Bett, Rima Youil, Natasha Persaud, Romnie Long, Mary-Ellen Davies, Robert K. Evans, Daniel C. Freed, Emilio A. Emini, Xu Liu, Michael J. Caulfield, Helen C. Perry, Henryk Mach, Keith A. Wilson, Liming Guan, William M. Hurni, Xiaoping Liang, Tong-Ming Fu, Ling Chen, David B. Volkin, Denise K. Nawrocki, Su Wang, Michael Chastain
Publikováno v:
Journal of virology. 77(11)
Cellular immune responses, particularly those associated with CD3 + CD8 + cytotoxic T lymphocytes (CTL), play a primary role in controlling viral infection, including persistent infection with human immunodeficiency virus type 1 (HIV-1). Accordingly,
Publikováno v:
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 49(5)
Differences between benign prostatic hyperplasia (BPH) and normal prostate tissue at the level of mRNA expression provide an opportunity to identify candidate genes for this disease. A cDNA subtraction procedure was used to isolate differentially exp