Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Timothy J. Pickering"'
Publikováno v:
Journal of Biological Chemistry. 274:17711-17717
T5 5′-3′-exonuclease is a member of a family of homologous 5′-nucleases essential for DNA replication and repair. We have measured the variation of the steady state parameters of the enzyme with pH. The log of the association constant of the en
Publikováno v:
Nucleic Acids Research. 27:730-735
Bacteriophage T5 5'-->3' exonuclease is a member of a family of sequence related 5'-nucleases which play an essential role in DNA replication. The 5'-nucleases have both exonucleolytic and structure-specific endo-nucleolytic DNA cleavage activity and
Autor:
Timothy J. Pickering, Dipak Patel, Jane A. Grasby, Jon R. Sayers, Mark R. Tock, Min Feng, Elaine Frary
Publikováno v:
Journal of molecular biology. 320(5)
The flap endonucleases, or 5′ nucleases, are involved in DNA replication and repair. They possess both 5′-3′ exonucleolytic activity and the ability to cleave bifurcated, or branched DNA, in an endonucleolytic, structure-specific manner. These
Autor:
Stephen C. Holmes, Karen J. Young, Timothy J. Pickering, Joseph S. Vyle, Jane A. Grasby, Olaf Merkel, Mark A. Cohen
Publikováno v:
Journal of molecular biology. 288(5)
The hairpin ribozyme is an example of a small catalytic RNA that catalyses the endonucleolytic transesterification of RNA in a highly sequence-specific manner. We have utilised chemical synthesis of RNA to create mutants of the hairpin ribozyme in wh
Autor:
Isabel K. McDonald, Timothy J. Pickering, Stephen C. Holmes, Karen J. Young, Joseph S. Vyle, Jane A. Grasby
Publikováno v:
Collection Symposium Series.
Publikováno v:
Biochemical Society Transactions. 29:A30-A30