Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Timothy J. Peters"'
Autor:
Timothy J. Peters, Braydon Meyer, Lauren Ryan, Joanna Achinger-Kawecka, Jenny Song, Elyssa M. Campbell, Wenjia Qu, Shalima Nair, Phuc Loi-Luu, Phillip Stricker, Elgene Lim, Clare Stirzaker, Susan J. Clark, Ruth Pidsley
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-23 (2024)
Abstract Background The Illumina family of Infinium Methylation BeadChip microarrays has been widely used over the last 15 years for genome-wide DNA methylation profiling, including large-scale and population-based studies, due to their ease of use a
Externí odkaz:
https://doaj.org/article/6f52a85a352f46848842385dfa8f78a7
Autor:
Ruth Pidsley, Dilys Lam, Wenjia Qu, Timothy J. Peters, Phuc‐Loi Luu, Darren Korbie, Clare Stirzaker, Roger J. Daly, Phillip Stricker, James G. Kench, Lisa G. Horvath, Susan J. Clark
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Background Prostate cancer is a clinically heterogeneous disease with a subset of patients rapidly progressing to lethal‐metastatic prostate cancer. Current clinicopathological measures are imperfect predictors of disease progression. Epig
Externí odkaz:
https://doaj.org/article/ce0e644fc6654c8a9b89ff431e3a8d9b
Autor:
Mayura V. Wagle, Stephin J. Vervoort, Madison J. Kelly, Willem Van Der Byl, Timothy J. Peters, Ben P. Martin, Luciano G. Martelotto, Simone Nüssing, Kelly M. Ramsbottom, James R. Torpy, Deborah Knight, Sinead Reading, Kevin Thia, Lisa A. Miosge, Debbie R. Howard, Renee Gloury, Sarah S. Gabriel, Daniel T. Utzschneider, Jane Oliaro, Jonathan D. Powell, Fabio Luciani, Joseph A. Trapani, Ricky W. Johnstone, Axel Kallies, Christopher C. Goodnow, Ian A. Parish
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Exhausted T cells arise when chronic activation triggers functional defects. Here the authors show that chronic antigenic stimulation in both tumour and infection models induces the expression of EGR2, which drives and stabilises exhausted cell epige
Externí odkaz:
https://doaj.org/article/835402bfc1a5448994d0c742c77cfabd
Autor:
Michael Radzieta, Fatemah Sadeghpour-Heravi, Timothy J. Peters, Honghua Hu, Karen Vickery, Thomas Jeffries, Hugh G. Dickson, Saskia Schwarzer, Slade O. Jensen, Matthew Malone
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Diabetic foot infections (DFIs) are a major cause of hospitalization and can lead to lower extremity amputation. In this pilot study, we used a multiomics approach to explore the host–microbe complex within DFIs. We observed minimal differ
Externí odkaz:
https://doaj.org/article/9d872203a61e4bfe96312e7f76c0ee92
Autor:
Amanda Khoury, Joanna Achinger-Kawecka, Saul A. Bert, Grady C. Smith, Hugh J. French, Phuc-Loi Luu, Timothy J. Peters, Qian Du, Aled J. Parry, Fatima Valdes-Mora, Phillippa C. Taberlay, Clare Stirzaker, Aaron L. Statham, Susan J. Clark
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The architectural protein CTCF is a mediator of chromatin conformation, but how CTCF binding to DNA is regulated remains poorly understood. Here the authors find that there is a shared subset of CTCF-bound sites resistant to protein depletion in diff
Externí odkaz:
https://doaj.org/article/8b6198ec146c403090e434c6de6028fa
Autor:
Ananda P. Dasanayake, Saman Warnakulasuriya, Colin K. Harris, Derek J. Cooper, Timothy J. Peters, Stanley Gelbier
Publikováno v:
International Journal of Dentistry, Vol 2010 (2010)
Alcohol and drug abuse are detrimental to general and oral health. Though we know the effects of these harmful habits on oral mucosa, their independent and combined effect on the dental caries experience is unknown and worthy of investigation. We com
Externí odkaz:
https://doaj.org/article/99ab5f3b59e64271acb6f24754b2da4c
Autor:
Timothy J. Peters, Ingvar Bjarnason
Publikováno v:
Canadian Journal of Gastroenterology, Vol 2, Iss 3, Pp 127-132 (1988)
Intestinal permeability has been assessed with three different classes of permeability probes, viz various sugar mixtures, 51Cr-EDTA and poly(ethylene glycol). The former two methods are having increasing clinical applications in the screening and as
Externí odkaz:
https://doaj.org/article/4653d86200c2492f9a2bd77a09c792c8
Autor:
Simon J. Pelham, Maria Soledad Caldirola, Danielle T. Avery, Joseph Mackie, Geetha Rao, Florian Gothe, Timothy J. Peters, Antoine Guerin, David Neumann, Doris Vokurkova, Vivian Hwa, Wenming Zhang, Shu-Chen Lyu, Iris Chang, Monali Manohar, Kari C. Nadeau, Maria Isabel Gaillard, Liliana Bezrodnik, Violeta Iotova, Norberto Walter Zwirner, Mavel Gutierrez, Waleed Al-Herz, Christopher C. Goodnow, Alexander Vargas-Hernández, Lisa R. Forbes Satter, Sophie Hambleton, Elissa K. Deenick, Cindy S. Ma, Stuart G. Tangye
Publikováno v:
Journal of Allergy and Clinical Immunology. 150:931-946
Lymphocyte differentiation is regulated by coordinated actions of cytokines and signaling pathways. IL-21 activates STAT1, STAT3, and STAT5 and is fundamental for the differentiation of human B cells into memory cells and antibody-secreting cells. Wh
Autor:
Michael Radzieta, Timothy J. Peters, Hugh G. Dickson, Allison J. Cowin, Lawrence A. Lavery, Saskia Schwarzer, Tara Roberts, Slade O. Jensen, Matthew Malone
Publikováno v:
APMIS. 130:383-396
Refereed/Peer-reviewed Cellular mechanisms and/or microbiological interactions which contribute to chronic diabetes related foot ulcers (DRFUs) were explored using serially collected tissue specimens from chronic DRFUs and control healthy foot skin.
Autor:
Matthew, Malone, Michael, Radzieta, Timothy J, Peters, Hugh G, Dickson, Saskia, Schwarzer, Slade O, Jensen, Lawrence A, Lavery
Publikováno v:
APMIS. 130:751-762
Virtually all diabetes-related foot ulcers (DRFUs) will become colonized by microorganisms that may increase the risk of developing an infection. The reasons why some ulcerations develop acute clinical infections (AI-DRFUs) whilst others develop chro