Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Timothy J. Nelson"'
Autor:
Jodi Scholz, Frank J. Secreto, Joan Wobig, Joe Kurian, Clint Hagen, Alexandra Zinnen, Don Vu, Steven J. Johnson, Frank Cetta, Yasir Qureshi, Rachel Reams, Bryan Cannon, Christina M. Heyer, Minhwang Chang, Numrah Fadra, Jennifer Coonen, Heather A. Simmons, Andres Mejia, Jennifer M. Hayes, Puja Basu, Saverio Capuano, Viktoriya Bondarenko, Jeanette M. Metzger, Timothy J. Nelson, Marina E. Emborg
Publikováno v:
Cell Transplantation, Vol 33 (2024)
Cardiac ventricular pressure overload affects patients with congenital heart defects and can cause cardiac insufficiency. Grafts of stem cell–derived cardiomyocytes are proposed as a complementary treatment to surgical repair of the cardiac defect,
Externí odkaz:
https://doaj.org/article/439629bc292c41d8a4faaeffc28551c6
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Congenital heart disease (CHD) are genetically complex and comprise a wide range of structural defects that often predispose to - early heart failure, a common cause of neonatal morbidity and mortality. Transcriptome studies of CHD in human pediatric
Externí odkaz:
https://doaj.org/article/ba4307ecacba48c4a8c4e2fe648a0fb2
Autor:
Saji Oommen, Susana Cantero Peral, Muhammad Y. Qureshi, Kimberly A. Holst, Harold M. Burkhart, Matthew A. Hathcock, Walter K. Kremers, Emma B. Brandt, Brandon T. Larsen, Joseph A. Dearani, Brooks S. Edwards, Joseph J. Maleszewski, Timothy J. Nelson
Publikováno v:
Cell Transplantation, Vol 31 (2022)
Congenital heart diseases, including single ventricle circulations, are clinically challenging due to chronic pressure overload and the inability of the myocardium to compensate for lifelong physiological demands. To determine the clinical relevance
Externí odkaz:
https://doaj.org/article/0ad959fde7064b8dba196e59cae044b6
Autor:
Teun M. Klein Gunnewiek, Eline J.H. Van Hugte, Monica Frega, Gemma Solé Guardia, Katharina Foreman, Daan Panneman, Britt Mossink, Katrin Linda, Jason M. Keller, Dirk Schubert, David Cassiman, Richard Rodenburg, Noemi Vidal Folch, Devin Oglesbee, Ester Perales-Clemente, Timothy J. Nelson, Eva Morava, Nael Nadif Kasri, Tamas Kozicz
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Epilepsy, intellectual and cortical sensory deficits, and psychiatric manifestations are the most frequent manifestations of mitochondrial diseases. How mitochondrial dysfunction affects neural structure and function remains elusive, mostly
Externí odkaz:
https://doaj.org/article/db72172982f844a182028f325789bcff
Autor:
Muhammad Y. Qureshi, MBBS, Allison K. Cabalka, MD, Shakila P. Khan, MD, Donald J. Hagler, MD, Dawit T. Haile, MD, Bryan C. Cannon, MD, Timothy M. Olson, MD, Susana Cantero-Peral, MD, PhD, Allan B. Dietz, PhD, Darcie J. Radel, MT, Nathan W. Taggart, MD, Angela M. Kelle, MD, Vilmarie Rodriguez, MD, Joseph A. Dearani, MD, Patrick W. O’Leary, MD, Timothy J. Nelson, MD, PhD, Karen M. Cavanaugh, CCRP, Jennifer M. Miller, MBA, Karen S. Miller, CCRP
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 1, Iss 2, Pp 185-191 (2017)
Myocardial dysfunction after Fontan palliation for univentricular congenital heart disease is a challenging clinical problem. The medical treatment has a limited impact, with cardiac transplant being the ultimate management step. Cell-based therapies
Externí odkaz:
https://doaj.org/article/4583cf19d33240d189725e5b790673f3
Autor:
Satsuki Yamada, D. Kent Arrell, Almudena Martinez‐Fernandez, Atta Behfar, Garvan C. Kane, Carmen M. Perez‐Terzic, Ruben J. Crespo‐Diaz, Robert J. McDonald, Saranya P. Wyles, Jelena Zlatkovic‐Lindor, Timothy J. Nelson, Andre Terzic
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 4, Iss 5, Pp n/a-n/a (2015)
Background Cardiac resynchronization therapy using bi‐ventricular pacing is proven effective in the management of heart failure (HF) with a wide QRS‐complex. In the absence of QRS prolongation, however, device‐based resynchronization is reporte
Externí odkaz:
https://doaj.org/article/615c629a0c2b46bbab865236d9e38cf6
Publikováno v:
Genomics Data, Vol 7, Iss , Pp 129-130 (2016)
The dataset includes microarray data (Affymetrix Mouse Genome 430 2.0 Array) from WT and Nos3−/− mouse embryonic heart ventricular tissues at 14.5 days post coitum (E14.5), induced pluripotent stem cells (iPSCs) derived from WT and Nos3−/− mo
Externí odkaz:
https://doaj.org/article/0fccc85c1146407c9d0bb06cf10804a6
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 3, Iss 3, p 24 (2016)
For more than a decade, stem cell therapy has been the focus of intensive efforts for the treatment of adult heart disease, and now has promise for treating the pediatric population. On the basis of encouraging results in the adult field, the applica
Externí odkaz:
https://doaj.org/article/c42203d17ada468db40c6a26d7a281d9
Autor:
Kathryn Edin, Timothy J. Nelson
Across the political spectrum, unwed fatherhood is denounced as one of the leading social problems of today. Doing the Best I Can is a strikingly rich, paradigm-shifting look at fatherhood among inner-city men often dismissed as'deadbeat dads.'Kathry
Publikováno v:
Stem cells and development. 31(17-18)
Lineage-specific differentiation of human-induced pluripotent stem cells (hiPSCs) into cardiomyocytes (CMs) offers a patient-specific model to dissect development and disease pathogenesis in a dish. However, challenges exist with this model system, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e240f675673184ebefafe85cb066e6f0
https://pubmed.ncbi.nlm.nih.gov/35726436
https://pubmed.ncbi.nlm.nih.gov/35726436