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pro vyhledávání: '"Timothy J. Mitchison"'
Akademický článek
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Autor:
Tai L. Ng, Erika J. Olson, Tae Yeon Yoo, H. Sloane Weiss, Yukiye Koide, Peter D. Koch, Nathan J. Rollins, Pia Mach, Tobias Meisinger, Trenton Bricken, Timothy Z. Chang, Colin Molloy, Jérôme Zürcher, Roger L. Chang, Timothy J. Mitchison, John I. Glass, Debora S. Marks, Jeffrey C. Way, Pamela A. Silver
Publikováno v:
mSystems, Vol 7, Iss 2 (2022)
ABSTRACT Suppression of the host innate immune response is a critical aspect of viral replication. Upon infection, viruses may introduce one or more proteins that inhibit key immune pathways, such as the type I interferon pathway. However, the abilit
Externí odkaz:
https://doaj.org/article/37ee1fa315624f72abfb551a9d58f267
Autor:
Timothy J. Mitchison
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-3 (2021)
Abstract Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed c
Externí odkaz:
https://doaj.org/article/c1afd6fec5b247c3ba1496124c3d6e48
Autor:
Gaurav Luthria, Ran Li, Stephanie Wang, Mark Prytyskach, Rainer H. Kohler, Douglas A. Lauffenburger, Timothy J. Mitchison, Ralph Weissleder, Miles A. Miller
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The regulation of microtubule (MT) dynamics in cancer cells within the tumor microenvironment is less understood. Here, the authors develop an imaging platform to examine MT dynamics in live xenograft models and show that pro-tumor macrophages modula
Externí odkaz:
https://doaj.org/article/6e12c582f93443ddbaa1e7221c686a84
Publikováno v:
eLife, Vol 10 (2021)
Traditional herbal medicines, which emphasize a holistic, patient-centric view of disease treatment, provide an exciting starting point for discovery of new immunomodulatory drugs. Progress on identification of herbal molecules with proven single age
Externí odkaz:
https://doaj.org/article/d6b0a2b6a13946478001a3f73cb6437e
Autor:
D E, Haines
Publikováno v:
The Anatomical record. 257(2)
Autor:
Mitchell, Judith M., Shaw, Jared T.
Publikováno v:
Angewandte Chemie. International Edition; March 2006, Vol. 45 Issue: 11 p1722-1726, 5p
Autor:
Rui Tong Quek, Kierra S. Hardy, Stephen G. Walker, Dan T. Nguyen, Taciani de Almeida Magalhães, Adrian Salic, Sujatha M. Gopalakrishnan, Pamela A. Silver, Timothy J. Mitchison
Publikováno v:
ACS Chemical Biology. 18:583-594
Publikováno v:
eLife, Vol 10 (2021)
Individual cancers rely on distinct essential genes for their survival. The Cancer Dependency Map (DepMap) is an ongoing project to uncover these gene dependencies in hundreds of cancer cell lines. To make this drug discovery resource more accessible
Externí odkaz:
https://doaj.org/article/7e72ff77e6a34087a230b2668f1f7acf
Autor:
James F Pelletier, Christine M Field, Sebastian Fürthauer, Matthew Sonnett, Timothy J Mitchison
Publikováno v:
eLife, Vol 9 (2020)
How bulk cytoplasm generates forces to separate post-anaphase microtubule (MT) asters in Xenopus laevis and other large eggs remains unclear. Previous models proposed that dynein-based, inward organelle transport generates length-dependent pulling fo
Externí odkaz:
https://doaj.org/article/ebff2a4644f64248bdb871588f6b6aab