Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Timothy J. Kopper"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Spinal cord injury (SCI) produces chronic, pro-inflammatory macrophage activation that impairs recovery. The mechanisms driving this chronic inflammation are not well understood. Here, we detail the effects of myelin debris on macrophage phy
Externí odkaz:
https://doaj.org/article/bcfad03edf464c22889b0e20e459344f
Autor:
Khaga R. Neupane, J. Robert McCorkle, Timothy J. Kopper, Jourdan E. Lakes, Surya P. Aryal, Masud Abdullah, Aaron A. Snell, John C. Gensel, Jill Kolesar, Christopher I. Richards
Publikováno v:
ACS Omega, Vol 6, Iss 5, Pp 3847-3857 (2021)
Externí odkaz:
https://doaj.org/article/9b5d98db7c904bb29dcb3b2180b04a5e
Autor:
Vincent J. Venditto, Dalia Haydar, Ahmed Abdel-Latif, John C. Gensel, Michael I. Anstead, Michelle G. Pitts, Jarrod Creameans, Timothy J. Kopper, Chi Peng, David J. Feola
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The rapid advancement of the COVID-19 pandemic has prompted an accelerated pursuit to identify effective therapeutics. Stages of the disease course have been defined by viral burden, lung pathology, and progression through phases of the immune respon
Externí odkaz:
https://doaj.org/article/8bba7113c29a42a38b4249dcd73eda9d
Autor:
Stephanie M. Davis, Lisa A. Collier, Edric D. Winford, Christopher C. Leonardo, Craig T. Ajmo, Elspeth A. Foran, Timothy J. Kopper, John C. Gensel, Keith R. Pennypacker
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-17 (2018)
Abstract Background The migration of peripheral immune cells and splenocytes to the ischemic brain is one of the major causes of delayed neuroinflammation after permanent large vessel stroke. Other groups have demonstrated that leukemia inhibitory fa
Externí odkaz:
https://doaj.org/article/edea01deedee49309c2e4a212436f76b
Autor:
Timothy J. Kopper, Katelyn E. McFarlane, William M. Bailey, Michael B. Orr, Bei Zhang, John C. Gensel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
After spinal cord injury (SCI), macrophages infiltrate into the lesion and can adopt a wide spectrum of activation states. However, the pro-inflammatory, pathological macrophage activation state predominates and contributes to progressive neurodegene
Externí odkaz:
https://doaj.org/article/2c4c687c08594057b2837a4dcb2234da
Publikováno v:
CNS Neuroscience & Therapeutics
Summary Introduction Azithromycin (AZM) and other macrolide antibiotics are applied as immunomodulatory treatments for CNS disorders. The immunomodulatory and antibiotic properties of AZM are purportedly independent. Aims To improve the efficacy and
Autor:
Michelle G. Pitts, David J. Feola, Michael I. Anstead, Timothy J. Kopper, John C. Gensel, Ahmed Abdel-Latif, Chi Peng, Jarrod W. Creameans, Vincent J. Venditto, Dalia Haydar
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology
Frontiers in Immunology
The rapid advancement of the COVID-19 pandemic has prompted an accelerated pursuit to identify effective therapeutics. Stages of the disease course have been defined by viral burden, lung pathology, and progression through phases of the immune respon
Autor:
Surya P. Aryal, Jill M. Kolesar, Timothy J. Kopper, Khaga R Neupane, Masud Abdullah, Christopher I. Richards, John C. Gensel, Jourdan E Lakes, J. Robert McCorkle, Aaron A Snell
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 5, Pp 3847-3857 (2021)
ACS Omega, Vol 6, Iss 5, Pp 3847-3857 (2021)
Macrophages, one of the most important phagocytic cells of the immune system, are highly plastic and are known to exhibit diverse roles under different pathological conditions. The ability to repolarize macrophages from pro-inflammatory (M1) to anti-
Publikováno v:
Scientific Reports
Spinal cord injury (SCI) produces chronic, pro-inflammatory macrophage activation that impairs recovery. The mechanisms driving this chronic inflammation are not well understood. Here, we detail the effects of myelin debris on macrophage physiology a
Autor:
John C. Gensel, Timothy J. Kopper
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 3, Pp 508-509 (2021)
Neural Regeneration Research
Neural Regeneration Research