Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Timothy J. Knott"'
Autor:
Ross W. Milne, Sally Robertson, James F. Scott, Clive R. Pullinger, Timothy J. Knott, L. M. Powell, D. P. R. Muller, Norman E. Miller, Philippa J. Talmud, Steve E. Humphries, Yves L. Marcel, S. Wallis, David R. Collins, Richard J. Pease, June K. Lloyd
Publikováno v:
Nucleic Acids Research. 16:8361-8375
Familial hypobetalipoproteinaemia is a rare autosomal dominant disorder in which levels of apo-B-containing plasma lipoproteins are approximately half-normal in heterozygotes and virtually absent in homozygotes. Here we describe mutations of the apo-
Publikováno v:
Biochemical and Biophysical Research Communications. 120:734-740
cDNA clones encoding human apolipoprotein AII have been isolated from an adult liver cDNA library. Apo AII mRNA was shown to be approximately 600 bases in length by RNA blot hybridisation. The intracellular precursor of apo AII was inferred from the
Publikováno v:
Nucleic Acids Research. 12:3909-3915
cDNA clones encoding human apolipoprotein CI have been isolated from an adult liver cDNA library. Apo CI mRNA was shown to have two species of approximately 580 and 560 bases by RNA blot hybridisation. The intracellular precursor of apo CI was inferr
Autor:
Carl-Henrik Heldin, Ann Johnsson, Rolf Ohlsson, Jonas Bergh, M. Bywater, Bengt Westermark, Christer Betsholtz, Graeme I. Bell, James Scott, Timothy J. Knott, Monica Pettersson
Publikováno v:
International Journal of Cancer. 39:502-507
U-1810, a human large-cell lung cancer line, was found to express a PDGF-like growth factor. 35S-cysteine labelling and immunoprecipitation revealed the synthesis and secretion of a 31-kDa PDGF-like protein. Serum-free conditioned medium contained PD
Autor:
James F. Scott, Timothy J. Knott, B. Levy-Wilson, Richard J. Pease, Brian J. McCarthy, S. Wallis, Robert W. Mahley, L. M. Powell
Publikováno v:
Biochemical Society Transactions. 15:195-199
Autor:
L. Priestley, James F. Scott, S. Wallis, M.E. Robertson, Leslie B. Rall, Mickey S. Urdea, Timothy J. Knott
Publikováno v:
Nucleic Acids Research. 13:6387-6398
The complete nucleotide sequence of the human apolipoprotein All gene together with 911 bases of 5' flanking sequence and 687 bases of 3' flanking sequence have been determined. The mRNA coding region is interrupted by three introns of 169, 293 and 3
Autor:
Timothy J. Knott, Stanley C. Rall, Thomas L. Innerarity, Shellie F. Jacobson, Mickey S. Urdea, Beatriz Levy-Wilson, Lyn M. Powell, Richard J. Pease, Roger Eddy, Hiroshi Nakai, Mary Byers, Linda M. Priestley, Elaine Robertson, Leslie B. Rall, Christer Betsholtz, Thomas B. Shows, Robert W. Mahley, James Scott
Publikováno v:
Science. 230:37-43
Apolipoprotein (apo-) B is the ligand responsible for the receptor-mediated catabolism of low density lipoproteins, the principal cholesterol-transporting lipoproteins in plasma. The primary structure of the carboxyl-terminal 30 percent (1455 amino a
Autor:
C. Fortier, Robert W. Mahley, L. Caiati, B. Levy-Wilson, B.D. Blackhart, Brian J. McCarthy, James F. Scott, Timothy J. Knott, V.R. Pierotti, E H Ludwig
Publikováno v:
DNA. 6:363-372
The sequence of the human apolipoprotein B gene comprises 43 kb divided into 29 exons, one of which is unusually long and contains 7572 bp. Comparison of the gene sequence with four complete and three partial cDNA sequences published elsewhere reveal
Autor:
L. Priestley, Richard J. Pease, L. M. Powell, Timothy J. Knott, H. Brunt, S. Wallis, James F. Scott
Publikováno v:
Nucleic acids research. 13(18)
Autor:
Yvonne H. Edwards, L. M. Powell, James F. Scott, Timothy J. Knott, Richard J. Pease, S. Wallis
Publikováno v:
Cell. 50(6)
Evidence suggests that intestinal apo-B48 is colinear with the amino-terminal half of hepatic apo-B100. To investigate the mechanism of apo-B48 production, we examined cDNA clones from human and rabbit small intestine. All clones contained a single C