Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Timothy J. Kelly"'
Publikováno v:
Cell Reports, Vol 29, Iss 9, Pp 2702-2717.e7 (2019)
Summary: Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through the analysis of progressive Argonaute (Ago)-miRNA depletion and rescue, including
Externí odkaz:
https://doaj.org/article/8d18ebdae34b458f9ec547a77a24f154
Publikováno v:
RNA
Argonaute (Ago) proteins interact with various binding partners and play a pivotal role in microRNA (miRNA)-mediated silencing pathways. By utilizing immunoprecipitation followed by mass spectrometry to determine cytoplasmic Ago2 protein complexes in
Publikováno v:
PMC
Argonaute (Ago) proteins mediate posttranscriptional gene repression by binding guide miRNAs to regulate targeted RNAs. To confidently assess Ago-bound small RNAs, we adapted a mouse embryonic stem cell system to express a single epitope-tagged Ago p
Publikováno v:
Cell reports, vol 29, iss 9
Cell reports
Cell Reports, Vol 29, Iss 9, Pp 2702-2717.e7 (2019)
Cell reports
Cell Reports, Vol 29, Iss 9, Pp 2702-2717.e7 (2019)
SUMMARY Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through the analysis of progressive Argonaute (Ago)-miRNA depletion and rescue, including s
Publikováno v:
Assessment & Evaluation in Higher Education. 39:641-656
Student evaluations of teaching are ubiquitous and impactful on the careers of college teachers. However, there is limited empirical research documenting the accuracy of people’s efforts in interpreting teaching evaluations. The current research co
Publikováno v:
Molecular and Cellular Biology. 31:2696-2706
Oxygen-dependent regulation of the transcription factor HIF-1α relies on a family of prolyl hydroxylases (PHDs) that hydroxylate hypoxia-inducible factor 1α (HIF-1α) protein at two prolines during normal oxygen conditions, resulting in degradation
Autor:
Timothy J. Kelly
Publikováno v:
AACN Clinical Issues: Advanced Practice in Acute and Critical Care. 8:71-77
"Not vain the weakest, if their force unite." Homer, Iliad (9th century, B.C.). In today's evolving health-care environment, the cardiac surgical intensive-care nurse is required to provide care to patients whose acuity levels are increasing. Simulta
Publikováno v:
The Journal of biological chemistry. 284(30)
Changes in expression levels of genes encoding for proteins that control metabolic pathways are essential to maintain nutrient and energy homeostasis in individual cells as well as in organisms. An important regulated step in this process is accompli
Autor:
Timothy J. Kelly, Juliette Urtis Kelly
Publikováno v:
AORN Journal. 54:61-74
Physicians and nurses need to be aware of the metabolic needs of the diabetic patient and incorporate those requirements into the plan of care during the perioperative period. With appropriate management, morbidity and mortality rates for diabetic pa