Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Timothy J. Hoon"'
Publikováno v:
Journal of Pharmacological Sciences, Vol 103, Iss 1, Pp 67-74 (2007)
To evaluate the pharmacokinetics, safety, and tolerability of solifenacin in patients with mild, moderate, or severe renal disease, eighteen patients with renal disease and six healthy volunteers Received a single oral dose of solifenacin (10 mg). Ph
Externí odkaz:
https://doaj.org/article/ead78f7113bd43bdafcfb18391459d63
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 4, Pp 405-412 (2006)
Determining the pharmacokinetics and safety of solifenacin succinate, a once-daily, oral antimuscarinic agent indicated for treatment of overactive bladder, in subjects with hepatic impairment. In this open-label study, 16 subjects (eight with modera
Autor:
Craig T. January, Timothy J. Hoon, Christian Studenik, Zhengfeng Zhou, V.R. Vorperian, Saeed Mohammad
Publikováno v:
Journal of the American College of Cardiology. 28(6):1556-1561
Objectives. Proarrhythmic effects have been observed with the selective histamine1 (H1) receptor antagonist drug astemizole, a widely prescribed antihistamine. The metabolites of astemizole and those of other antihistamine compounds have not been imp
Autor:
Timothy J. Hoon, Stuart Rich, Bradley G. Phillips, Bruce J. Schrader, Marieke Dekker Schoen, Jerry L. Bauman
Publikováno v:
The American Journal of Cardiology. 77:996-999
In patients with primary pulmonary hypertension who respond to nifedipine during acute drug testing, there is a significant linear correlation of serum nifedipine concentration with pulmonary artery pressure and resistance. Although most demonstrate
Autor:
Timothy J. Hoon, Edward J. Brown, Bradley G. Phillips, Josephine M. Yim, Jerry L. Bauman, Neville Bittar, Peter H. Vlasses, Catherine Celestin
Publikováno v:
American Heart Journal. 131:872-878
Optimal drug therapy for patients with acute myocardial infarction (AMI) is well described in the medical literature. However, data on the actual pharmacologic management of patients surviving AMI at academic hospitals is unavailable. The purpose of
Autor:
James H. Fischer, Timothy J. Hoon, Jerry L. Bauman, Marieke Dekker Schoen, Deborah A. Piscitelli
Publikováno v:
The Journal of Clinical Pharmacology. 34:823-828
This study further characterized the impact of concentration-dependent protein binding on the bioavailability and clinical use of the immediate-release (IR) and controlled-release (CR) dosage forms of disopyramide after single doses and during steady
Autor:
Josephine M. Yim, Peter H. Vlasses, Bradley G. Phillips, Timothy J. Hoon, Edward J. Brown, Jerry L. Bauman, Neville Bittar, Catherine Celestin
Publikováno v:
The American Journal of Cardiology. 75:1184-1186
The present study found that a significant percentage of patients with myocardial infarction, who according to the results of large-scale clinical trials should benefit from ACE inhibitor therapy, did not receive such treatment at discharge.
Autor:
Timothy J. Hoon, Josefina Ramos, Firyal S. Khan-Dawood, M. Yusoff Dawood, Randal L. Batenhorst
Publikováno v:
Journal of clinical pharmacology. 33(11)
Five postmenopausal women received single doses of a 0.675 mg estradiol hydroxypropyl-beta-cyclodextrin (estradiol-HP beta CD) sublingual tablet by the sublingual and oral route. A single dose of a 1 mg micronized estradiol tablet was given orally fo
Autor:
Bruce J. Schrader, Vicki L. Just, Jerry L. Bauman, Timothy J. Hoon, Frank Paloucek, Jerrold B. Leikin
Publikováno v:
The American journal of emergency medicine. 9(2)
Oral nifedipine (N) and clonidine (C) are often used in the treatment of hypertensive urgencies; however, until recently, there were no comparative studies using the same patient population. The authors reviewed the records of hypertensive patients t
Autor:
Timothy J. Hoon, Karen J. Beckman, Robert B. Parker, Robert J. Hariman, Jerry L. Bauman, Marieke Dekker Schoen
Publikováno v:
The American journal of cardiology. 67(4)
To evaluate the effects of calcium pretreatment on the disposition and electrocardiographic effects of verapamil, 8 healthy male volunteers received treatment in each of 3 phases in a randomized, double-blind, crossover manner. Phase I denoted 10 ml