Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Timothy J. Hanly"'
Successful Diatom Transcription Factor Synthesis and Downstream Cloning Using the BioXp™ 3200 System
Autor:
Hong Zheng, Stephane C. Lefebvre, Sarah R. Smith, Timothy J. Hanly, Yo Suzuki, Andrew E. Allen
Publikováno v:
BioTechniques, Vol 59, Iss 1, Pp 46-47 (2015)
Externí odkaz:
https://doaj.org/article/6ebcb940f9db4e61a08a5ff64ca95b68
Validation and Optimization of a Yeast Dynamic Flux Balance Model using a Parallel Bioreactor System
Publikováno v:
IFAC Proceedings Volumes. 46:113-118
The availability of parallel fermentation systems comprised of miniature, independently controlled bioreactors provides new opportunities for high throughput bioprocess development. In this study, we demonstrated the use of a four bioreactor system t
Autor:
Michael A. Henson, Timothy J. Hanly
Publikováno v:
IFAC Proceedings Volumes. 46:157-162
A defined mixed culture of specialized microbes that exploits the native capabilities of each member species is a promising alternative to use of a single engineered microbe for cellulosic biofuels production. We explored such a synthetic consortium
Publikováno v:
Applied Microbiology and Biotechnology. 93:2529-2541
Current researches into the production of biochemicals from lignocellulosic feedstocks are focused on the identification and engineering of individual microbes that utilize complex sugar mixtures. Microbial consortia represent an alternative approach
Autor:
Michael A. Henson, Timothy J. Hanly
Publikováno v:
Biotechnology and Bioengineering. 108:376-385
Sequential uptake of pentose and hexose sugars that compose lignocellulosic biomass limits the ability of pure microbial cultures to efficiently produce value-added bioproducts. In this work, we used dynamic flux balance modeling to examine the capab
Autor:
Nacyra Assad-Garcia, Ray-Yuan Chuang, Bogumil J. Karas, Kim S. Wise, Vladimir N. Noskov, Timothy J. Hanly, Hamilton O. Smith, Jason Stam, Michael G. Montague, Maxim Kostylev, Gregory M. Goldgof, Yo Suzuki, J. Craig Venter, R. Alexander Richter, John I. Glass, Sanjay Vashee, Nico J. Enriquez, Adi Ramon, Daniel G. Gibson, Clyde A. Hutchison, Elizabeth A. Winzeler
Publikováno v:
Genome research. 25(3)
Complexities of natural biological systems make it difficult to understand and define precisely the roles of individual genes and their integrated functions. The use of model organisms with a relatively small number of genes enables the isolation of
Autor:
Michael A. Henson, Timothy J. Hanly
Publikováno v:
IET Syst Biol
Dynamic flux balance analysis (DFBA) is an extension of classical flux balance analysis that allows the dynamic effects of the extracellular environment on microbial metabolism to be predicted and optimised. Recently this computational framework has
Autor:
Vadim N. Gladyshev, Ayako Murao, Timothy J. Hanly, Yo Suzuki, Vyacheslav M. Labunskyy, Frederick P. Roth
Publikováno v:
G3: Genes|Genomes|Genetics
Being a simple eukaryotic organism, Saccharomyces cerevisiae provides numerous advantages for expression and functional characterization of proteins from higher eukaryotes, including humans. However, studies of complex exogenous pathways using yeast
Successful Diatom Transcription Factor Synthesis and Downstream Cloning Using the BioXp™ 3200 System
Autor:
Sarah R. Smith, Yo Suzuki, Hong Zheng, Andrew E. Allen, Stephane C. Lefebvre, Timothy J. Hanly
Publikováno v:
BioTechniques. 59:46-47
Autor:
Timothy J, Hanly, Michael A, Henson
Publikováno v:
Biotechnology and bioengineering. 111(2)
Inhibitory compounds that result from biomass hydrolysis are an obstacle to the efficient production of second-generation biofuels. Fermentative microorganisms can reduce compounds such as furfural and 5-hydroxymethyl furfural (HMF), but detoxificati