Výsledky vyhledávání - "Timothy J. Blake"

The Environmental Degradability of Demnum, a Typical Pfpe Polymer

Autor: Nobuhiko Tsuda, YOSHITAKA HONDA, Edward Schaefer, Peizhi Lian, Asmaa Muneer, Timothy J. Blake, Loubna A. Hammad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e6cbfc6299a6760144cfe004c93bbc56
https://doi.org/10.2139/ssrn.4414914

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Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the β-subunit of the GM-CSF receptor

Autor: Thomas J. Gonda, Brendan J. Jenkins, Timothy J. Blake, Richard J D'Andrea

Publikováno v: Journal of Leukocyte Biology. 72:1246-1255

Several reports have suggested an interaction between the erythropoietin receptor (EpoR) and the shared signaling subunit (hβc) of the human granulocyte macrophage-colony stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors, although

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad1bbe406b4d9c9a0cac1d760504d371
https://doi.org/10.1189/jlb.72.6.1246

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Saturation Mutagenesis of the β Subunit of the Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Shows Clustering of Constitutive Mutations, Activation of ERK MAP Kinase and STAT Pathways, and Differential β Subunit Tyrosine Phosphorylation

Autor: Brendan J. Jenkins, Timothy J. Blake, Thomas J. Gonda

Publikováno v: Blood. 92:1989-2002

The high-affinity receptors for human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 are heterodimeric complexes consisting of cytokine-specific  subunits and a common signal-transducing β subunit (hβc)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13818876a230ec640fd3e722e5648591
https://doi.org/10.1182/blood.v92.6.1989

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(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 3. Evidence for the involvement of a sulfenic acid in their reactions

Autor: Kurt Klemm, Uwe Krueger, Volker Dr Figala, Georg Rainer, Hartmann Schaefer, Bernhard Kohl, Ernst Sturm, Joerg Senn-Bilfinger, Timothy J. Blake

Publikováno v: The Journal of Organic Chemistry. 55:4163-4168

Reactions impliquant les sulfenamides cycliques, limitant leur duree de vie et impliquant un acide sulfenique dans la formation de thiosulfinates qui se decomposent en disulfures symetriques. Analyse des produits de dimerisation en presence de thiols

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::02138f51985378c3d617286a79793177
https://doi.org/10.1021/jo00300a038

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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation

Autor: Anna L. Brown, Michelle M. Le Beau, Bao-Tran H. Truong, David B. Shultz, Timothy J. Blake, Thomas J. Gonda, Scott C. Kogan, Vernon T. Phan

Publikováno v: Molecular and cellular biology. 23(13)

We utilized a mouse model of acute promyelocytic leukemia (APL) to investigate how aberrant activation of cytokine signaling pathways interacts with chimeric transcription factors to generate acute myeloid leukemia. Expression in mice of the APL-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769ebc8331e4be707e1812d08762b5a7
https://pubmed.ncbi.nlm.nih.gov/12808098

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Functional cross-talk between cytokine receptors revealed by activating mutations in the extracellular domain of the beta-subunit of the GM-CSF receptor

Autor: Timothy J, Blake, Brendan J, Jenkins, Richard J, D'Andrea, Thomas J, Gonda

Publikováno v: Journal of leukocyte biology. 72(6)

Several reports have suggested an interaction between the erythropoietin receptor (EpoR) and the shared signaling subunit (hbeta(c)) of the human granulocyte macrophage-colony stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors, altho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ff3c5091e2eedae118970e12922465ab
https://pubmed.ncbi.nlm.nih.gov/12488507

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Two symmetrical conformations of the triostin antibiotics in solution

Autor: Timothy J. Blake, John R. Kalman, Dudley H. Williams

Publikováno v: Tetrahedron Letters. 18:2621-2624

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d97f5f34c18f891b4161f7622dc71a57
https://doi.org/10.1016/s0040-4039(01)83837-5

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(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 1. Their reaction with thiols under acidic conditions. Disulfide containing 2-pyridiniobenzimidazolides as mimics for the inhibited enzyme

Autor: Bernhard Kohl, Ernst Sturm, Joerg Senn-Bilfinger, Volker Dr Figala, Timothy J. Blake, Georg Rainer, Hartmann Schaefer, Kurt Klemm, Uwe Krueger

Publikováno v: The Journal of Organic Chemistry. 52:4573-4581

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42521b4c7933b50883568e1be8943668
https://doi.org/10.1021/jo00229a026

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Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA

Autor: Alexander A. Morley, Roger D. Drinkwater, Timothy J. Blake, David R. Turner

Publikováno v: Mutation research. 219(1)

The amount of 5-methylated cytosine (5 mC) in the sequence CmCGG has been measured in DNA extracted from uncultured peripheral blood human lymphocytes obtained from 24 young (mean age 25) and 22 old (mean age 75) individuals. When compared with the y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfcee2ea11bdb4b55ce7db872116dc6
https://pubmed.ncbi.nlm.nih.gov/2911269

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