Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Timothy J. Bensman"'
Autor:
Mansour A. Dughbaj, Jordanna G. Jayne, A Young J. Park, Timothy J. Bensman, Marquerita Algorri, Andre J. Ouellette, Michael E. Selsted, Paul M. Beringer
Publikováno v:
Antibiotics, Vol 10, Iss 9, p 1043 (2021)
Vicious cycles of chronic airway obstruction, lung infections with Pseudomonas aeruginosa, and neutrophil-dominated inflammation contribute to morbidity and mortality in cystic fibrosis (CF) patients. Rhesus theta defensin-1 (RTD-1) is an antimicrobi
Externí odkaz:
https://doaj.org/article/f41e8ed08e9e4187b2214ab78cd6cc90
Autor:
Justin C. Earp, Eliford Kitabi, Dakshina Chilukuri, Timothy J Bensman, Elizabeth O’Shaughnessy, Leslie Ball, Philip M Colangelo, Yuliya Yasinskaya, Kellie S. Reynolds, Heidi Smith
Publikováno v:
Clinical Infectious Diseases. 73:903-906
For treatment of severe malaria, the World Health Organization recommends 3 mg/kg intravenous artesunate in pediatric patients weighing less than 20 kg. Here we describe the Food and Drug Administration’s rationale for selecting 2.4 mg/kg in pediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f18c46a84618e71c9937cae2bc0065
https://doi.org/10.1093/cid/ciab149
https://doi.org/10.1093/cid/ciab149
Autor:
Eliford Kitabi, Timothy J Bensman, Justin C Earp, Dakshina M Chilukuri, Heidi Smith, Leslie Ball, Elizabeth O’Shaughnessy, Yuliya Yasinskaya, Kellie S Reynolds
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 75(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08828091321ecca1fa4f4ef8d67ef9cb
https://pubmed.ncbi.nlm.nih.gov/35023549
https://pubmed.ncbi.nlm.nih.gov/35023549
Publikováno v:
Antimicrob Agents Chemother
Effective bacterial infection eradication requires not only potent antibacterial agents but also proper dosing strategies. Current practices generally utilize point estimates of the effects of therapeutic agents, even though the actual kinetics of ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b07663f5d04bc5037c04c0f1306a4d99
https://europepmc.org/articles/PMC7449204/
https://europepmc.org/articles/PMC7449204/
Autor:
Kimberly A Struble, Su-Young Choi, David McMillan, Timothy J Bensman, Eric F. Donaldson, Hanan Ghantous, Mark Seaton, Thamban Valappil, Laine Myers, Julian J. O'Rear, Debra Birnkrant, Patrick R. Harrington, Yu Cao, Kirk M Chan-Tack
Publikováno v:
Antiviral Research. 195:105182
The development and approval of brincidofovir for the treatment of smallpox, a disease that was eradicated from the world over 40 years ago, has resulted in the second antiviral approved via the Medical Countermeasure Initiative (MCMi) to combat this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd6950ca96bf936746a2eea95ee509c
https://doi.org/10.1016/j.antiviral.2021.105182
https://doi.org/10.1016/j.antiviral.2021.105182
Autor:
Michael E. Selsted, Timothy J Bensman, A. Young J. Park, Marquerita Algorri, Jordanna G. Jayne, Paul M. Beringer, Mansour A. Dughbaj, Andre J. Ouellette
Publikováno v:
Antibiotics, Vol 10, Iss 1043, p 1043 (2021)
Antibiotics
Volume 10
Issue 9
Antibiotics
Volume 10
Issue 9
Vicious cycles of chronic airway obstruction, lung infections with Pseudomonas aeruginosa, and neutrophil-dominated inflammation contribute to morbidity and mortality in cystic fibrosis (CF) patients. Rhesus theta defensin-1 (RTD-1) is an antimicrobi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fca440a19e3c30770c17c0c67d81bbe
https://doi.org/10.3390/antibiotics10091043
https://doi.org/10.3390/antibiotics10091043
Autor:
Timothy J. Bensman, Dat Q. Tran, Paul M. Beringer, Nicole Denovel, Annie Wong-Beringer, Michael E. Selsted, Rosemary C. She, Melissa Agnello, Henry Ho, Samuel M. Moskowitz, Albert Nguyen
Publikováno v:
Journal of Antimicrobial Chemotherapy. 71:181-188
OBJECTIVES Chronic endobronchial infections with Pseudomonas aeruginosa contribute to bronchiectasis and progressive loss of lung function in patients with cystic fibrosis. This study aimed to evaluate the therapeutic potential of a novel macrocyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e53ee7b4de977ad248b6e246738f7a
https://doi.org/10.1093/jac/dkv301
https://doi.org/10.1093/jac/dkv301
Autor:
Joshua Wang, David Z. D'Argenio, Paul M. Beringer, Adupa P. Rao, Timothy J. Bensman, Lynn Fukushima, Jordanna G. Jayne
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Acute pulmonary exacerbations (APE) involving Pseudomonas aeruginosa are associated with increased morbidity and mortality in cystic fibrosis (CF) patients. Drug resistance is a significant challenge to treatment. Ceftazidime-avibactam (CZA) demonstr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2b92f7cb2a6848cee52edd9fe5e72b9
https://doi.org/10.1128/aac.00988-17
https://doi.org/10.1128/aac.00988-17
Autor:
Paul M. Beringer, Joshua Meinert, Michael E. Selsted, Omid Akbari, Justin B. Schaal, Timothy J. Bensman, Elza Kimura, Adupa P. Rao, Jordanna G. Jayne, Dat Q. Tran, Meiling Sun, Joshua C. Wang
Publikováno v:
Antimicrobial Agents and Chemotherapy
Chronic airway infection and inflammation contribute to the progressive loss of lung function and shortened survival of patients with cystic fibrosis (CF). Rhesus theta defensin-1 (RTD-1) is a macrocyclic host defense peptide with antimicrobial and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbeb8ceaffc5b70b6a3248d67ad97c82
https://doi.org/10.1128/aac.00154-17
https://doi.org/10.1128/aac.00154-17
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 25:377-382
A hallmark of cystic fibrosis is the massive recruitment of neutrophils into the lung compartment in response to chronic Pseudomonas aeruginosa infection. The overexuberant neutrophilic response results in release of proteases (e.g. neutrophil elasta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696dd8a0f048195a6df9f3296556d780
https://doi.org/10.1016/j.pupt.2012.06.010
https://doi.org/10.1016/j.pupt.2012.06.010