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pro vyhledávání: '"Timothy J. Bemand"'
Autor:
Delfine Cheng, Wolfgang A. Linke, Inken G. Huttner, Gunjan Trivedi, Marion von Frieling-Salewsky, Christine E. Seidman, Jonathan G. Seidman, Daniel Hesselson, Timothy J. Bemand, Renee Johnson, Filip Braet, Karen Hillcoat, Kevin Alford, Diane Fatkin, Christopher S. Hayward, Claire Horvat, Louis W. Wang, Celine F. Santiago, Michael P. Feneley
Publikováno v:
Circulation: Genomic and Precision Medicine. 11
Background Truncating variants in the TTN gene ( TTNtv) are common in patients with dilated cardiomyopathy (DCM) but also occur in the general population. Whether TTNtv are sufficient to cause DCM or require a second hit for DCM manifestation is an i