Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Timothy J Collier"'
Autor:
Natosha M. Mercado, Carlye Szarowicz, Jennifer A. Stancati, Caryl E. Sortwell, Samuel A. Boezwinkle, Timothy J. Collier, Margaret E. Caulfield, Kathy Steece-Collier
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-16 (2024)
Abstract The rs6265 single nucleotide polymorphism (SNP) in the gene for brain-derived neurotrophic factor is a common variant that alters therapeutic outcomes for individuals with Parkinson’s disease (PD). We previously investigated the effects of
Externí odkaz:
https://doaj.org/article/04243b627f4647388bacb505772446ee
Autor:
Irving E Vega, Timothy J Collier
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Externí odkaz:
https://doaj.org/article/2118c647d1684fe2b31b3bdeaec295cb
Autor:
Timothy J Collier, D Eugene Redmond, Kathy eSteece-Collier, Jack W Lipton, Fredric P Manfredsson
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Accumulation of alpha-synuclein (α-syn) in Lewy bodies and neurites of midbrain dopamine neurons is diagnostic for Parkinson’s disease (PD), leading to the proposal that PD is a toxic gain-of-function synucleinopathy. Here we discuss the alternati
Externí odkaz:
https://doaj.org/article/6318624867a240628bc0394886f972f9
Autor:
Nicholas M Kanaan, Timothy J Collier, Allyson Cole-Strauss, Tessa Grabinski, Zachary R Mattingly, Mary E Winn, Kathy Steece-Collier, Caryl E Sortwell, Fredric P Manfredsson, Jack W Lipton
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127768 (2015)
We hypothesized that the study of gene expression at 1, 2, 4, 6 and 16 weeks in the substantia nigra (SN) after intrastriatal 6-OHDA in the Sprague-Dawley rat (rattus norvegicus) would identify cellular responses during the degenerative process that
Externí odkaz:
https://doaj.org/article/3a085edc373645ee9b23290bc05eea36
Autor:
D Luke Fischer, Timothy J Collier, Allyson Cole-Strauss, Susan L Wohlgenant, Jack W Lipton, Kathy Steece-Collier, Fredric P Manfredsson, Christopher J Kemp, Caryl E Sortwell
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133957 (2015)
Deep brain stimulation (DBS) is the most common neurosurgical treatment for Parkinson's disease (PD). Whereas the globus pallidus interna (GPi) has been less commonly targeted than the subthalamic nucleus (STN), a recent clinical trial suggests that
Externí odkaz:
https://doaj.org/article/9be54ed838814595b2172eabb7e5d897
Autor:
Lalitha Madhavan, Brian F Daley, Beverly L Davidson, Ryan L Boudreau, Jack W Lipton, Allyson Cole-Strauss, Kathy Steece-Collier, Timothy J Collier
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137136 (2015)
The expression of soluble growth and survival promoting factors by neural precursor cells (NPCs) is suggested to be a prominent mechanism underlying the protective and regenerative effects of these cells after transplantation. Nevertheless, how and t
Externí odkaz:
https://doaj.org/article/d53849eccd9d4d67ad703563bcd3b726
Autor:
Margaret E. Caulfield, Molly J. Vander Werp, Jennifer A. Stancati, Timothy J. Collier, Caryl E. Sortwell, Ivette M. Sandoval, Fredric P. Manfredsson, Kathy Steece-Collier
Publikováno v:
Neurobiology of Disease, Vol 181, Iss , Pp 106111- (2023)
In the past 25 years, the prevalence of Parkinson's disease (PD) has nearly doubled. Age remains the primary risk factor for PD and as the global aging population increases this trend is predicted to continue. Even when treated with levodopa, the gol
Externí odkaz:
https://doaj.org/article/0a32cba2dcf34119b5bce4aa489fc00e
Autor:
João Pedro Ferreira, John G.F. Cleland, Nicolas Girerd, Pierpaolo Pellicori, Mark R. Hazebroek, Job Verdonschot, Timothy J. Collier, Johannes Petutschnigg, Andrew L. Clark, Jan A. Staessen, Stephane Heymans, Patrick Rossignol, Faiez Zannad
Publikováno v:
American Journal of Cardiology, 191, 39-42. Excerpta Medica, Elsevier Science
The QRS duration can be easily obtained from a 12-lead electrocardiogram. Increased QRS duration reflects greater ventricular activation times and often ventricular dyssyn-chrony. Dyssynchrony causes an impairment of the global cardiac function and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915e9fba5ee37986bad8800f0c496eb7
https://doi.org/10.1016/j.amjcard.2022.12.016
https://doi.org/10.1016/j.amjcard.2022.12.016
Autor:
Stuart J. Pocock, João Pedro Ferreira, Timothy J. Collier, Christiane E. Angermann, Jan Biegus, Sean P. Collins, Mikhail Kosiborod, Michael E. Nassif, Piotr Ponikowski, Mitchell A. Psotka, John R. Teerlink, Jasper Tromp, John Gregson, Jonathan P. Blatchford, Cordula Zeller, Adriaan A. Voors
Publikováno v:
European Journal of Heart Failure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dae2ecfd6234911e2d82b54a5cebbf46
https://doi.org/10.1002/ejhf.2853
https://doi.org/10.1002/ejhf.2853
Autor:
João Pedro Ferreira, John G. F. Cleland, Nicolas Girerd, Pierpaolo Pellicori, Mark R. Hazebroek, Job Verdonschot, Timothy J. Collier, Johannes Petutschnigg, Andrew L. Clark, Jan A. Staessen, Stephane Heymans, Faiez Zannad, Patrick Rossignol
Publikováno v:
Clinical research in cardiology. Springer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc10e661a0d87d953b04e97634b304
https://doi.org/10.1007/s00392-022-02116-w
https://doi.org/10.1007/s00392-022-02116-w