Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Timothy J A, Chico"'
Autor:
Gareth J Williams, BMBS, Abdulaziz Al-Baraikan, MSc, Frank E Rademakers, ProfMD, Fabio Ciravegna, ProfPhD, Frans N van de Vosse, ProfPhD, Allan Lawrie, ProfPhD, Alexander Rothman, PhD, Euan A Ashley, ProfDphil, Martin R Wilkins, ProfMD, Patricia V Lawford, ProfPhD, Stig W Omholt, ProfPhD, Ulrik Wisløff, ProfPhD, D Rodney Hose, ProfPhD, Timothy J A Chico, ProfMD, Julian P Gunn, ProfMD, Paul D Morris, PhD
Publikováno v:
The Lancet: Digital Health, Vol 5, Iss 7, Pp e467-e476 (2023)
Summary: The past decade has seen a dramatic rise in consumer technologies able to monitor a variety of cardiovascular parameters. Such devices initially recorded markers of exercise, but now include physiological and health-care focused measurements
Externí odkaz:
https://doaj.org/article/2dae23871e944ee9a8e3aa1c127e5a9a
Autor:
Ryan O. Snodgrass, Karan Govindpani, Karen Plant, Elisabeth C. Kugler, Changmin Doh, Thomas Dawson, Luis E. McCormack, Helen M. Arthur, Timothy J. A. Chico
Publikováno v:
Disease Models & Mechanisms, Vol 16, Iss 4 (2023)
Externí odkaz:
https://doaj.org/article/ee242943edf346f0a36a4522901556da
Autor:
Megan E. Hughes, Timothy J. A. Chico
Publikováno v:
Sensors, Vol 23, Iss 19, p 8154 (2023)
Physical activity and cardiovascular disease (CVD) are intimately linked. Low levels of physical activity increase the risk of CVDs, including myocardial infarction and stroke. Conversely, when CVD develops, it often reduces the ability to be physica
Externí odkaz:
https://doaj.org/article/17c650e0a9a2406491e6c4b72cc60bbb
Autor:
Peter D. Winter, Timothy J. A. Chico
Publikováno v:
Sensors, Vol 23, Iss 14, p 6333 (2023)
A digital twin is a computer-based “virtual” representation of a complex system, updated using data from the “real” twin. Digital twins are established in product manufacturing, aviation, and infrastructure and are attracting significant atte
Externí odkaz:
https://doaj.org/article/51022618fc814e8ca1977c36b8abf407
Publikováno v:
Sensors, Vol 23, Iss 12, p 5752 (2023)
Cardiovascular diseases kill 18 million people each year. Currently, a patient’s health is assessed only during clinical visits, which are often infrequent and provide little information on the person’s health during daily life. Advances in mobil
Externí odkaz:
https://doaj.org/article/73a97ec2e9474a11be8b576855390890
Autor:
Aaron M. Savage, Sathishkumar Kurusamy, Yan Chen, Zhen Jiang, Karishma Chhabria, Ryan B. MacDonald, Hyejeong R. Kim, Heather L. Wilson, Fredericus J. M. van Eeden, Angel L. Armesilla, Timothy J. A. Chico, Robert N. Wilkinson
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Calcium signalling downstream of VEGF is essential for VEGF-induced angiogenesis. Here Savage et al. show that Transmembrane Protein 33 (TMEM33) is required for angiogenesis and the endothelial calcium response to VEGF, revealing a function for TMEM3
Externí odkaz:
https://doaj.org/article/47f0ef6f17ce4a149e51a23dc2a30f3c
Autor:
Jian-Dong Huang, Jinling Wang, Elaine Ramsey, Gerard Leavey, Timothy J. A. Chico, Joan Condell
Publikováno v:
Sensors, Vol 22, Iss 20, p 8002 (2022)
Cardiovascular disease (CVD) is the world’s leading cause of mortality. There is significant interest in using Artificial Intelligence (AI) to analyse data from novel sensors such as wearables to provide an earlier and more accurate prediction and
Externí odkaz:
https://doaj.org/article/860c0409157b49c0925a73a9c06e5304
Autor:
Karishma Chhabria, Avgoustinos Vouros, Caroline Gray, Ryan B. MacDonald, Zhen Jiang, Robert Neil Wilkinson, Karen Plant, Eleni Vasilaki, Clare Howarth, Timothy J. A. Chico
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 9 (2019)
Diabetes is associated with dysfunction of the neurovascular unit, although the mechanisms of this are incompletely understood and currently no treatment exists to prevent these negative effects. We previously found that the nitric oxide (NO) donor s
Externí odkaz:
https://doaj.org/article/eb6ba7eb9fea4bbeada40664c7fd4c91
Autor:
Nikolay V. Ogryzko, Emily E. Hoggett, Sara Solaymani-Kohal, Simon Tazzyman, Timothy J. A. Chico, Stephen A. Renshaw, Heather L. Wilson
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 2, Pp 259-264 (2014)
Interleukin-1 (IL-1), the ‘gatekeeper’ of inflammation, is the apical cytokine in a signalling cascade that drives the early response to injury or infection. Expression, processing and secretion of IL-1 are tightly controlled, and dysregulated IL
Externí odkaz:
https://doaj.org/article/608b59b3ac31454fa7bea21e45ba45db
Autor:
Allan Lawrie, Elizabeth Kugler, George Bowley, Emily S. Noël, Jovana Serbanovic-Canic, Freek van Eeden, Timothy J. A. Chico, Paul C. Evans, Robert N. Wilkinson
Publikováno v:
British Journal of Pharmacology. 179:900-917
Mammalian models including non-human primates, pigs and rodents have been used extensively to study the mechanisms of cardiovascular disease. However, there is an increasing desire for alternative model systems that provide excellent scientific value
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92d17d1b77d2aacc67fd0c167f36c521
https://doi.org/10.1111/bph.15473
https://doi.org/10.1111/bph.15473