Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Timothy J, McGovern"'
Autor:
Xilin Li, Xiaobo He, Yuan Le, Xiaoqing Guo, Matthew S. Bryant, Aisar H. Atrakchi, Timothy J. McGovern, Karen L. Davis-Bruno, David A. Keire, Robert H. Heflich, Nan Mei
Publikováno v:
Archives of Toxicology. 96:3077-3089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3908f5062d649f1b6b4553f2182a494f
https://doi.org/10.1007/s00204-022-03347-6
https://doi.org/10.1007/s00204-022-03347-6
Autor:
David Jones, William J. Brock, Stephanie N Harris, Simon Authier, Wendy G. Halpern, Michael K. Pugsley, Timothy J. McGovern, Pamela D McGovern
Publikováno v:
International Journal of Toxicology. 40:487-505
The growth in drug development over the past years reflects significant advancements in basic sciences and a greater understanding of molecular pathways of disease. Benchmarking industry practices has been important to enable a critical reflection on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c900297e24b5839cdb9dfacb4ba3999f
https://doi.org/10.1177/10915818211043435
https://doi.org/10.1177/10915818211043435
Autor:
Xilin Li, Yuan Le, Ji-Eun Seo, Xiaoqing Guo, Yuxi Li, Si Chen, Roberta A. Mittelstaedt, Nyosha Moore, Sharon Guerrero, Audrey Sims, Sruthi T. King, Aisar H. Atrakchi, Timothy J. McGovern, Karen L. Davis-Bruno, David A. Keire, Rosalie K. Elespuru, Robert H. Heflich, Nan Mei
Publikováno v:
Regulatory Toxicology and Pharmacology. 141:105410
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d0da53ed2d8091ded46be2e2ff9bb85
https://doi.org/10.1016/j.yrtph.2023.105410
https://doi.org/10.1016/j.yrtph.2023.105410
Autor:
Xilin, Li, Xiaobo, He, Yuan, Le, Xiaoqing, Guo, Matthew S, Bryant, Aisar H, Atrakchi, Timothy J, McGovern, Karen L, Davis-Bruno, David A, Keire, Robert H, Heflich, Nan, Mei
Publikováno v:
Archives of toxicology. 96(11)
Many nitrosamines are recognized as mutagens and potent rodent carcinogens. Over the past few years, nitrosamine impurities have been detected in various drugs leading to drug recalls. Although nitrosamines are included in a 'cohort of concern' becau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d456755bece44b1faf1138cba369d278
https://pubmed.ncbi.nlm.nih.gov/35882637
https://pubmed.ncbi.nlm.nih.gov/35882637
Publikováno v:
International Journal of Toxicology. 30:600-610
Excipients are used in all drug products and in most food products. New technologies are being tested to increase the amount or rate of absorption of drugs and new and novel excipients may be included among them. New physical approaches such as nanop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c2c60204211919cf0794d6af105b8a
https://doi.org/10.1177/1091581811423582
https://doi.org/10.1177/1091581811423582
Publikováno v:
Campus-Wide Information Systems. 15:103-107
Without reliable electronic records, colleges and universities will be unable to manage and defend themselves ‐ they will lose their memories and be at significant risk. The authors explain the problems associated with the continuing reliability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a82849c5816608dec041f8d2f4030e
https://doi.org/10.1108/10650749810227170
https://doi.org/10.1108/10650749810227170
Autor:
Timothy J. McGovern
Publikováno v:
Leachables and Extractables Handbook: Safety Evaluation, Qualification, and Best Practices Applied to Inhalation Drug Products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7348808824d9b90b74cbaf67e15f11c
https://doi.org/10.1002/9781118147672.ch8
https://doi.org/10.1002/9781118147672.ch8
Publikováno v:
International journal of toxicology. 28(6)
This symposium focuses on the management of genotoxic impurities in the synthesis of pharmaceuticals. Recent developments in both Europe and United States require sponsors of new drug applications to develop processes to control the risks of potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d664badb46c3820ecc2b0ebbf8aa6b
https://pubmed.ncbi.nlm.nih.gov/19966139
https://pubmed.ncbi.nlm.nih.gov/19966139