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pro vyhledávání: '"Timothy J, Eyes"'
Autor:
Timothy J, Eyes, James I, Austerberry, Rebecca J, Dearman, Linus O, Johannissen, Ian, Kimber, Noel, Smith, Angela, Thistlethwaite, Jeremy P, Derrick
Publikováno v:
Molecular Immunology
Highlights • Aggregation of an exemplar therapeutic antibody fragment (scFv) enhances immunogenicity in vivo. • Epitope mapping reveals immunogenicity is directed to a specific epitope in aggregate species. • Molecular simulation demonstrates b