Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Timothy J, Carrothers"'
Autor:
Manana, Giorgobiani, Margaret H, Burroughs, Tinatin, Antadze, Timothy J, Carrothers, Todd A, Riccobene, Rinal, Patel, Tao, Lin, Penka, Stefanova
Publikováno v:
Pediatric Infectious Disease Journal. 42:199-205
Acute bacterial skin and skin structure infections (ABSSSIs) are a significant source of morbidity in children. Dalbavancin, approved for the treatment of adults and children with ABSSSI, has a well-established safety profile in adults. We report saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf771d4ebf2879688572c58af65db55
https://doi.org/10.1097/inf.0000000000003798
https://doi.org/10.1097/inf.0000000000003798
Publikováno v:
Pediatric Infectious Disease Journal. 42:99-105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bf5ec93874a01c34e9fddc3bcce8fff
https://doi.org/10.1097/inf.0000000000003764
https://doi.org/10.1097/inf.0000000000003764
Autor:
Priya Vijayvargiya, Margaret Breen-Lyles, Sara Linker Nord, Daniel Maselli, Irene Busciglio, Ramesh Boinpally, Anna Muslin, Timothy J. Carrothers, Michael Camilleri
Publikováno v:
Digestive Diseases and Sciences. 67:3911-3921
Eluxadoline, a peripherally acting, mixed µ- and κ-opioid receptor (OR) agonist and δ-OR antagonist, is approved for treatment of adults with irritable bowel syndrome-diarrhea (IBS-D). About a third of IBS-D patients has bile acid diarrhea (BAD);
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d177100821c770b3fc99059b1af0f7f
https://doi.org/10.1007/s10620-022-07379-x
https://doi.org/10.1007/s10620-022-07379-x
Autor:
Shampa Das, Todd Riccobene, Timothy J. Carrothers, James G. Wright, Merran MacPherson, Andrew Cristinacce, Lynn McFadyen, Rujia Xie, Alison Luckey, Susan Raber
Purpose A series of iterative population pharmacokinetic (PK) modelling and probability of target attainment (PTA) analyses were undertaken to support dose optimization for aztreonam-avibactam, a combination antibiotic. Methods Joint PTA analyses (pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f44009c65371c38d29145c4cdcd0f535
https://doi.org/10.21203/rs.3.rs-2406580/v1
https://doi.org/10.21203/rs.3.rs-2406580/v1
Publikováno v:
Paediatric Drugs
Community-acquired pneumonia (CAP)/community-acquired bacterial pneumonia (CABP) and complicated skin and soft tissue infection (cSSTI)/acute bacterial skin and skin structure infection (ABSSSI) represent major causes of morbidity and mortality in ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d861a6add83966773a8e8f0cbcb4c8c
http://europepmc.org/articles/PMC8563558
http://europepmc.org/articles/PMC8563558
Publikováno v:
Clinical Pharmacology in Drug Development
The key pharmacokinetic/pharmacodynamic (PK/PD) efficacy index for β‐lactam antibiotics is the percentage of time that free drug concentrations exceed the minimum inhibitory concentration (MIC) of bacteria during each dosing interval (fT>MIC). Cef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890be20a6dfab07830883cf6c5d19591
https://doi.org/10.1002/cpdd.907
https://doi.org/10.1002/cpdd.907
Autor:
Timothy J. Carrothers, Luann Phillips, Tatiana Khariton, Antonia Periclou, Margit Kapás, Parviz Ghahramani
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Cariprazine, a dopamine D3-preferring D3/D2 receptor partial agonist, is approved for the treatment of adults with schizophrenia (1.5–6 mg/day) and manic/mixed (3–6 mg/day) episodes associated with bipolar I disorder. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e591bbf0fcb17832b6e1f4891c9df0
https://doi.org/10.1007/s13318-020-00650-4
https://doi.org/10.1007/s13318-020-00650-4
Autor:
Willie Earley, Julie Passarell, Parviz Ghahramani, Suresh Durgam, Antonia Periclou, Tatiana Khariton, David J. Jaworowicz, Margit Kapás, Susan Willavize, Timothy J. Carrothers
Publikováno v:
Clinical and Translational Science, Vol 13, Iss 2, Pp 362-371 (2020)
Clinical and Translational Science
Clinical and Translational Science
Population pharmacokinetic/pharmacodynamic modeling (via NONMEM) was used to describe longitudinal exposure-response relationships for total cariprazine (sum of cariprazine and its major active metabolites) in 2,558 patients with schizophrenia or bip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975dfc0263df8d0b876c831e9a392558
https://doaj.org/article/723d33f3a14e43b0947d2293e493193c
https://doaj.org/article/723d33f3a14e43b0947d2293e493193c
Autor:
Manoli Vourvahis, Timothy J. Carrothers, Lynn McFadyen, John S. Bradley, Mark Lovern, Todd Riccobene, Susan Raber, Richard C. Franzese, Kenny J. Watson, Phylinda L. S. Chan
Publikováno v:
Clinical pharmacology and therapeutics, vol 111, iss 3
Increasing prevalence of infections caused by antimicrobial-resistant gram-negative bacteria represents a global health crisis, and while several novel therapies that target various aspects of antimicrobial resistance have been introduced in recent y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596328c6515dcf6576a4e0e2e86d82c2
https://escholarship.org/uc/item/456322xv
https://escholarship.org/uc/item/456322xv
Autor:
Jonathan M. Meyer, Willie Earley, Timothy J. Carrothers, Ágota Barabássy, Rakesh Jain, Mehul Patel, Christoph U. Correll, Antonia Periclou
Publikováno v:
Neuropsychiatric Disease and Treatment
Christoph U Correll,1–3 Rakesh Jain,4 Jonathan M Meyer,5 Antonia Periclou,6 Timothy Carrothers,6 Ágota Barabássy,7 Mehul Patel,8 Willie Earley91Department of Psychiatry, Northwell Health, The Zucker Hillside Hospital, Glen Oaks, NY, USA; 2Hofstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eabadbc60d09d10ea0d05b9b5459d13
https://doi.org/10.2147/ndt.s210340
https://doi.org/10.2147/ndt.s210340