Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Timothy J, Brocksom"'
Publikováno v:
Reaction Chemistry & Engineering. 8:790-797
The continuous photooxygenation reactions of (+) and (−)-α-pinenes are described, giving the corresponding (+) and (−)-pinocarvones (83% yield) and (+) and (−)-pinocarveols (61% yield). Scaled-up and long-term experiments (24 h) are also prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8523a4e6f40548f718a076550fc0ae88
https://doi.org/10.1039/d2re00385f
https://doi.org/10.1039/d2re00385f
Publikováno v:
Organic Letters. 24:8331-8336
An advantageous and original synthesis of fentanyl is described. This new approach includes two efficient continuous flow reductive aminations achieved via photoredox catalysis and a final batch acylation. A telescoped protocol for the two photocatal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad58a588300ac35811ece32d3ef39a4
https://doi.org/10.1021/acs.orglett.2c03338
https://doi.org/10.1021/acs.orglett.2c03338
Multicomponent Reactions Applied to Total Synthesis of Biologically Active Molecules: A Short Review
Autor:
Giovanni W. Amarante, Juliana A. dos Santos, Pedro P. de Castro, Kleber T. de Oliveira, Timothy J. Brocksom
Publikováno v:
Current Topics in Medicinal Chemistry. 23
Abstract: Multicomponent reactions (MCRs) are processes in which three or more starting materials are combined in the same reaction vessel, forming an adduct that contains all or most of the atoms of the starting materials. MCRs are one-pot processes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5115e34f30aa2873154a6ec6e0ced2c4
https://doi.org/10.2174/1568026623666230403102437
https://doi.org/10.2174/1568026623666230403102437
Autor:
Aline A. N. de Souza, Aloisio de A. Bartolomeu, Timothy J. Brocksom, Timothy Noël, Kleber T. de Oliveira
Publikováno v:
Journal of Organic Chemistry, 87(9), 5856-5865. American Chemical Society
We investigated the electrochemical sulfenylation reaction in both batch and continuous flow regimes, involving thiophenols/thiols and enol-acetates to yield α-sulfenylated ketones, without using additional oxidants or catalysts. Studies with differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b86ae30f5a2930d6700e05cc4c7779
https://hdl.handle.net/11245.1/28e42b2f-42bc-48f8-bc66-2913e5abf1c2
https://hdl.handle.net/11245.1/28e42b2f-42bc-48f8-bc66-2913e5abf1c2
Autor:
Guilherme M. Martins, Maria F. A. Magalhães, Timothy J. Brocksom, Vanderlei S. Bagnato, Kleber T. de Oliveira
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Herein we report a machine-assisted and scaled-up synthesis of propofol, a short-acting drug used in procedural sedation, which is extensively in demand during this COVID-19 pandemic. The continuous-flow protocol proved to be efficient, with great po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4759d9024385208f3d17ceded5057531
https://pubmed.ncbi.nlm.nih.gov/35873601
https://pubmed.ncbi.nlm.nih.gov/35873601
Autor:
Glauco Machado, Anita J. Marsaioli, Dávila S. Zampieri, Timothy J. Brocksom, Felipe C. Wouters, Daniele F. O. Rocha
Publikováno v:
Molecules, Vol 18, Iss 9, Pp 11429-11451 (2013)
Benzoquinones are usually present in arthropod defence exudates. Here, we describe the chemical profiles of 12 harvestman species belonging to the neotropical family Gonyleptidae. Nine of the studied species produced benzoquinones, while three produc
Externí odkaz:
https://doaj.org/article/e4c8e9aa5b60402da59d9a110114399b
Autor:
Anderson R. Aguillón, Rodrigo O. M. A. de Souza, Raquel A. C. Leão, Timothy J. Brocksom, Kleber T. de Oliveira, Leandro S. M. Miranda
Publikováno v:
Organic Process Research & Development. 24:2017-2024
We have investigated the synthesis of p-mentha-2,8-dien-1-ol (1) as a cannabidiol precursor by photochemical oxidation of (R)-limonene (2) with singlet oxygen (1O2) using meso-tetraphenylporphyrin ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::642289c2066ca15e4ee3104d0aad6e0f
https://doi.org/10.1021/acs.oprd.0c00131
https://doi.org/10.1021/acs.oprd.0c00131
Autor:
Timothy J. Brocksom, Kleber T. de Oliveira, Rodrigo C. Silva, Aloisio de A. Bartolomeu, Luely Oliveira da Silva
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 917-955 (2020)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
In this review we present relevant and recent applications of porphyrin derivatives as photocatalysts in organic synthesis, involving both single electron transfer (SET) and energy transfer (ET) mechanistic approaches. We demonstrate that these highl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1a5856c7587ee9f3f9f9ebec3761ee
https://doaj.org/article/d7b6bc8baaec4ddbb39b563568da5b5d
https://doaj.org/article/d7b6bc8baaec4ddbb39b563568da5b5d
Autor:
Barbara Sayuri Bellete, Timothy J. Brocksom, Jhuly Wellen Ferreira Lacerda, Evandro Luiz Dall'Oglio, Lucas Campos Curcino Vieira, Leonardo Gomes de Vasconcelos, Olívia Moreira Sampaio, Marciana P. Uliana
Publikováno v:
Brazilian Journal of Development. 6:32516-32530
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183f7b3ef5cb90d346fc9b048c1ef273
https://doi.org/10.34117/bjdv6n5-628
https://doi.org/10.34117/bjdv6n5-628
Autor:
Timothy Noël, Rodrigo C. Silva, Timothy J. Brocksom, Kleber T. de Oliveira, Aloisio de A. Bartolomeu
Publikováno v:
Journal of Organic Chemistry, 84(16), 10459-10471. American Chemical Society
A metal-free methodology for the photoarylation of pyridines, in water, is described giving 2 and 4-arylated-pyridines in yields up to 96%. The scope of the aryldiazonium salts is presented showing important results depending on the nature and positi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c7f248f9c4b9da972abf410a2def64
http://www.scopus.com/inward/record.url?scp=85070866463&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85070866463&partnerID=8YFLogxK