Výsledky vyhledávání - "Timothy Howells"

Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury

Autor: Fartein Velle, Anders Lewén, Timothy Howells, Anders Hånell, Pelle Nilsson, Per Enblad

Publikováno v: Journal of Neurosurgery: Pediatrics. :1-11

OBJECTIVE The management of cerebral perfusion pressure (CPP) is a challenge in children with traumatic brain injury (TBI) because the normal blood pressure is age dependent and the role of cerebral pressure autoregulation (CPA) is unclear. In this s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0ecb69213ea4bc17d0c4f08342e6161
https://doi.org/10.3171/2023.1.peds22352

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Cerebral Blood Flow and Oxygen Delivery in Aneurysmal Subarachnoid Hemorrhage: Relation to Neurointensive Care Targets

Autor: Teodor Svedung Wettervik, Henrik Engquist, Anders Hånell, Timothy Howells, Elham Rostami, Elisabeth Ronne-Engström, Anders Lewén, Per Enblad

Publikováno v: Neurocritical Care. 37:281-292

Background The primary aim was to determine to what extent continuously monitored neurointensive care unit (neuro-ICU) targets predict cerebral blood flow (CBF) and delivery of oxygen (CDO2) after aneurysmal subarachnoid hemorrhage. The secondary aim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22ed74a5713ef9df4b4e8b7a904d98e
https://doi.org/10.1007/s12028-022-01496-1

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Higher Intracranial Pressure Variability is Associated with Lower Cerebrovascular Resistance in Aneurysmal Subarachnoid Hemorrhage

Autor: Teodor, Svedung Wettervik, Henrik, Engquist, Timothy, Howells, Anders, Hånell, Elham, Rostami, Elisabeth, Ronne-Engström, Anders, Lewén, Per, Enblad

Higher intracranial pressure variability (ICPV) has been associated with a more favorable cerebral energy metabolism, lower rate of delayed ischemic neurologic deficits, and more favorable outcome in aneurysmal subarachnoid hemorrhage (aSAH). We have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b2d366b28f228be04371cd6416366f
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-491007

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Autoregulatory or Fixed Cerebral Perfusion Pressure Targets in Traumatic Brain Injury: Determining Which Is Better in an Energy Metabolic Perspective

Autor: Timothy Howells, Per Enblad, Lars Hillered, Elham Rostami, Teodor Svedung Wettervik, Anders Lewén

Publikováno v: Journal of Neurotrauma. 38:1969-1978

Current guidelines in traumatic brain injury (TBI) recommend a cerebral perfusion pressure (CPP) within the fixed interval of 60-70 mm Hg. However, the autoregulatory, optimal CPP target (CPPopt) might yield better cerebral blood flow (CBF) regulatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2530d73bb504207cde65ae7eeae19cd5
https://doi.org/10.1089/neu.2020.7290

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Akademický článek

The Correlation between Cerebral Blood Flow Measured by Bedside Xenon-CT and Brain Chemistry Monitored by Microdialysis in the Acute Phase following Subarachnoid Hemorrhage

Autor: Elham Rostami, Henrik Engquist, Timothy Howells, Elisabeth Ronne-Engström, Pelle Nilsson, Lars Tomas Hillered, Anders Lewén, Per Enblad

Publikováno v: Frontiers in Neurology, Vol 8 (2017)

Cerebral microdialysis (MD) may be used in patients suffering from subarachnoid hemorrhage (SAH) to detect focal cerebral ischemia. The cerebral MD catheter is usually placed in the right frontal lobe and monitors the area surrounding the catheter. T

Externí odkaz: https://doaj.org/article/7ac45d3bfd47493b9652c8eadd231e72

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Temporal effects of barbiturate coma on intracranial pressure and compensatory reserve in children with traumatic brain injury

Autor: Per Enblad, Timothy Howells, Fartein Velle, Anders Lewén, Pelle Nilsson

Publikováno v: Acta Neurochirurgica

Background The aim was to study the effects of barbiturate coma treatment (BCT) on intracranial pressure (ICP) and intracranial compensatory reserve (RAP index) in children (< 17 years of age) with traumatic brain injury (TBI) and refractory intracra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c554135e6e0dfe59aa341e1d8e727e
https://doi.org/10.1007/s00701-020-04677-z

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Females Exhibit Better Cerebral Pressure Autoregulation, Less Mitochondrial Dysfunction, and Reduced Excitotoxicity after Severe Traumatic Brain Injury

Autor: Teodor Svedung Wettervik, Anders Hånell, Timothy Howells, Per Enblad, Anders Lewén

Publikováno v: Journal of neurotrauma. 39(21-22)

The aim of the study was to investigate sex-related differences in intracranial pressure (ICP) dynamics, cerebral pressure autoregulation (PRx55-15), cerebral energy metabolism, and clinical outcome after severe traumatic brain injury (TBI). One-hund

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfdf20199eba0f5b7b1b465979e7ee8
https://pubmed.ncbi.nlm.nih.gov/35587145

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