Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Timothy H Holtz"'
Autor:
Wanna Leelawiwat, Sarika Pattanasin, Anuwat Sriporn, Punneeporn Wasinrapee, Oranuch Kongpechsatit, Famui Mueanpai, Jaray Tongtoyai, Timothy H Holtz, Marcel E Curlin
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201386 (2018)
BACKGROUND:Differences between HIV genotypes may affect HIV disease progression. We examined infecting HIV genotypes and their association with disease progression in a cohort of men who have sex with men with incident HIV infection in Bangkok, Thail
Externí odkaz:
https://doaj.org/article/eb23bb70d6ad4d9fa25bce23489d20d9
Autor:
Dominique B Figueroa, Joseph Tillotson, Maoji Li, Estelle Piwowar-Manning, Craig W Hendrix, Timothy H Holtz, Kevin Bokoch, Linda-Gail Bekker, Frits van Griensven, Sharon Mannheimer, James P Hughes, Robert M Grant, Namandjé N Bumpus
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195764 (2018)
Tenofovir (TFV), a nucleotide reverse transcriptase inhibitor, requires two phosphorylation steps to form a competitive inhibitor of HIV reverse transcriptase. Adenylate kinase 2 (AK2) has been previously demonstrated to phosphorylate tenofovir to te
Externí odkaz:
https://doaj.org/article/5c4afdf43275489faacaf0ba13a21d5d
Autor:
Alex Carballo-Diéguez, Ivan C Balán, William Brown, Rebecca Giguere, Curtis Dolezal, Cheng-Shiun Leu, Mark A Marzinke, Craig W Hendrix, Jeanna M Piper, Barbra A Richardson, Cynthia Grossman, Sherri Johnson, Kailazarid Gomez, Stephanie Horn, Ratiya Pamela Kunjara Na Ayudhya, Karen Patterson, Cindy Jacobson, Linda-Gail Bekker, Suwat Chariyalertsak, Anupong Chitwarakorn, Pedro Gonzales, Timothy H Holtz, Albert Liu, Kenneth H Mayer, Carmen Zorrilla, Javier Lama, Ian McGowan, Ross D Cranston
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181607 (2017)
Trials to assess microbicide safety require strict adherence to prescribed regimens. If adherence is suboptimal, safety cannot be adequately assessed. MTN-017 was a phase 2, randomized sequence, open-label, expanded safety and acceptability crossover
Externí odkaz:
https://doaj.org/article/8958a3b5e21d4547a26797f9d40b2f47
Autor:
Llang B Maama-Maime, Mathabo Mareka, Julia V Ershova, Thabong E Tlali, Kekeletso Kao, Mamakhetha Phalatse, Lauren Polansky, Laura K Beres, Moselinyane Letsie, Timothy H Holtz
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133808 (2015)
Drug resistance is an increasing threat to tuberculosis (TB) control worldwide. The World Health Organization advises monitoring for drug resistance, with either ongoing surveillance or periodic surveys.The antituberculosis drug resistance survey was
Externí odkaz:
https://doaj.org/article/ea1a38dd15da4dcc8070d127fc24ecbb
Autor:
Shama D Ahuja, David Ashkin, Monika Avendano, Rita Banerjee, Melissa Bauer, Jamie N Bayona, Mercedes C Becerra, Andrea Benedetti, Marcos Burgos, Rosella Centis, Eward D Chan, Chen-Yuan Chiang, Helen Cox, Lia D'Ambrosio, Kathy DeRiemer, Nguyen Huy Dung, Donald Enarson, Dennis Falzon, Katherine Flanagan, Jennifer Flood, Maria L Garcia-Garcia, Neel Gandhi, Reuben M Granich, Maria G Hollm-Delgado, Timothy H Holtz, Michael D Iseman, Leah G Jarlsberg, Salmaan Keshavjee, Hye-Ryoun Kim, Won-Jung Koh, Joey Lancaster, Christophe Lange, Wiel C M de Lange, Vaira Leimane, Chi Chiu Leung, Jiehui Li, Dick Menzies, Giovanni B Migliori, Sergey P Mishustin, Carole D Mitnick, Masa Narita, Philly O'Riordan, Madhukar Pai, Domingo Palmero, Seung-kyu Park, Geoffrey Pasvol, Jose Peña, Carlos Pérez-Guzmán, Maria I D Quelapio, Alfredo Ponce-de-Leon, Vija Riekstina, Jerome Robert, Sarah Royce, H Simon Schaaf, Kwonjune J Seung, Lena Shah, Tae Sun Shim, Sonya S Shin, Yuji Shiraishi, José Sifuentes-Osornio, Giovanni Sotgiu, Matthew J Strand, Payam Tabarsi, Thelma E Tupasi, Robert van Altena, Martie Van der Walt, Tjip S Van der Werf, Mario H Vargas, Pirett Viiklepp, Janice Westenhouse, Wing Wai Yew, Jae-Joon Yim, Collaborative Group for Meta-Analysis of Individual Patient Data in MDR-TB
Publikováno v:
PLoS Medicine, Vol 9, Iss 8, p e1001300 (2012)
BACKGROUND:Treatment of multidrug resistant tuberculosis (MDR-TB) is lengthy, toxic, expensive, and has generally poor outcomes. We undertook an individual patient data meta-analysis to assess the impact on outcomes of the type, number, and duration
Externí odkaz:
https://doaj.org/article/0c1649a3d81f4690960357151985ced7
Publikováno v:
PLoS Medicine, Vol 5, Iss 1 (2008)
Externí odkaz:
https://doaj.org/article/7c842d767ce249b3a408fa56950b0407
Autor:
Timothy H Holtz
Publikováno v:
PLoS Medicine, Vol 4, Iss 4, p e161 (2007)
Externí odkaz:
https://doaj.org/article/3759d8faf5d94bb6b654ccb6979dbb3b
Publikováno v:
PLoS Medicine, Vol 3, Iss 10, p e419 (2006)
Externí odkaz:
https://doaj.org/article/68d9b5bba1bd4a5ca9cbd2aaaf57fca3
Autor:
Mary T, Glenshaw, Paul, Gaist, Amber, Wilson, Robert C, Cregg, Timothy H, Holtz, Maureen M, Goodenow
Publikováno v:
JAIDS Journal of Acquired Immune Deficiency Syndromes. 90:S9-S16
In 2019, approximately 1.2 M persons were living with HIV and an estimated 34,800 new HIV infections occurred in the United States (U.S.). Significant disparities in HIV burden exist among persons of color, those with male-to-male sexual contact, you
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d2154e99048556a469b26131bcdb85
https://doi.org/10.1097/qai.0000000000002960
https://doi.org/10.1097/qai.0000000000002960
Autor:
Jill L. Schwartz, Timothy H. Holtz, Ian McGowan, Craig W. Hendrix, Marcel E. Curlin, Mark A. Marzinke, Gustavo F. Doncel, Ratiya Pamela Kunjara Na Ayudhya, Rhonda M. Brand, James F. Rooney, Boonyos Raengsakulrach, Anupong Chitwarakorn, Ross D Cranston, Jeanna M. Piper, Sherri Johnson
Publikováno v:
AIDS Res Hum Retroviruses
The Microbicide Trials Network-017 study was undertaken to characterize the safety, acceptability, pharmacokinetic (PK), and pharmacodynamic profile of the reduced-glycerin (RG) 1% tenofovir (RG-TFV) gel compared to oral emtricitabine/tenofovir disop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c3d88224449cc3ca3a93d6448e36ff
https://doi.org/10.1089/aid.2021.0115
https://doi.org/10.1089/aid.2021.0115