Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Timothy H Helms"'
Autor:
Kerry L Simon, Matthew R Cook, Brian D Husbands, Mackenzie E Long, Jessica A Hokamp, Timothy H Helms, Heather R Shive, Sarah Lumbrezer Johnson, Eric Hostnik, Laura E Selmic
Publikováno v:
Journal of Feline Medicine and Surgery Open Reports, Vol 8 (2022)
Case summary A 7-year-old male castrated domestic shorthair cat presented with a 5-day history of inappetence. A mid-abdominal mass was palpated and, on exploratory laparotomy, a cystic mass arising from the root of the mesentery was observed. The ma
Externí odkaz:
https://doaj.org/article/bf2bc0e10f9347b4be1eb05e5248658e
Autor:
Douglas J Brusich, Ashlyn M Spring, Thomas D James, Catherine J Yeates, Timothy H Helms, C Andrew Frank
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://doaj.org/article/8e84afdcc7674cc9a7d61507fc3ce816
Autor:
Thomas A. Mace, Samuel K. Kulp, Yizhen Guo, Sophia G. Liva, Trang Vu, Alyssa Marie M Castillo, Uma L Subrayan, Justin Thomas, Timothy H. Helms, Min Chen, Kyeongmin Kim, Zhiliang Xie, Christopher C. Coss, Travis Costa, Bryan Remaily, Mitch A. Phelps, Donald J. Irby, Dwight H. Owen
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 2, Pp 232-244 (2021)
Jcsm Rapid Communications
Jcsm Rapid Communications
Background Monoclonal antibody (mAb) immune checkpoint inhibitor (ICI) therapies have dramatically impacted oncology this past decade. However, only about one‐third of patients respond to treatment, and biomarkers to predict responders are lacking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5e047c2fd7517629863afea5696c35
https://doaj.org/article/db94475297f14a02937ba2decc4f78d7
https://doaj.org/article/db94475297f14a02937ba2decc4f78d7
Autor:
Jennifer M. Thomas-Ahner, Mitch A. Phelps, Dana M. LeMoine, Samuel K. Kulp, Riley D. Mullins, Fabienne Lucas, Steven K. Clinton, Timothy H. Helms, Zhiliang Xie, Moray J. Campbell, Nathan Schmidt, Surafel Getaneh, Christopher C. Coss
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
A promotional role for androgen receptor (AR) signaling in hepatocellular carcinogenesis is emerging. In pre-clinical models, including diethylnitrosamine- (DEN-) induced hepatocellular carcinoma (HCC), anti-androgen therapies delay hepatocarcinogene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aab2fd58e41af176c4c9f978f7fbf1e
https://doaj.org/article/c25b0208e10b4d27952527a2f7974c56
https://doaj.org/article/c25b0208e10b4d27952527a2f7974c56
Autor:
Timothy H. Helms, Sandra F. Diaz, John D. Bonagura, Rebecca Kohnken, Rachel E. Cianciolo, Jessie Scaglione
Publikováno v:
Journal of the American Veterinary Medical Association. 253(2)
CASE DESCRIPTION A 2.5-year-old 12-kg (26.4-lb) castrated male Miniature American Shepherd was referred because of a 3-week history of a localized crusted skin lesion on the digital pad of digit 3 of the right hind limb. CLINICAL FINDINGS Skin lesion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dc94ea6473d3453b8c8f3fd0efed693
https://pubmed.ncbi.nlm.nih.gov/29963946
https://pubmed.ncbi.nlm.nih.gov/29963946
Autor:
Douglas J Brusich, Thomas D. James, Ashlyn M. Spring, Timothy H. Helms, C. Andrew Frank, Catherine J. Yeates
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afa289e63554deee5d9ba76c598891a6
https://doi.org/10.1101/141366
https://doi.org/10.1101/141366
Autor:
C. Andrew Frank, Ashlyn M. Spring, Douglas J. Brusich, Timothy H. Helms, Thomas D. James, Catherine J. Yeates
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
PLoS Genetics, Vol 14, Iss 8, p e1007577 (2018)
Gain-of-function mutations in the human CaV2.1 gene CACNA1A cause familial hemiplegic migraine type 1 (FHM1). To characterize cellular problems potentially triggered by CaV2.1 gains of function, we engineered mutations encoding FHM1 amino-acid substi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9927de23c394e9c5fcc523b87ea75189
https://doi.org/10.1371/journal.pgen.1007577
https://doi.org/10.1371/journal.pgen.1007577
Autor:
Alyssa Marie M. Castillo, Trang T. Vu, Sophia G. Liva, Min Chen, Zhiliang Xie, Justin Thomas, Bryan Remaily, Yizhen Guo, Uma L. Subrayan, Travis Costa, Timothy H. Helms, Donald J. Irby, Kyeongmin Kim, Dwight H. Owen, Samuel K. Kulp, Thomas A. Mace, Mitch A. Phelps, Christopher C. Coss
Publikováno v:
JCSM Rapid Communications, Vol 4, Iss 2, Pp 232-244 (2021)
Abstract Background Monoclonal antibody (mAb) immune checkpoint inhibitor (ICI) therapies have dramatically impacted oncology this past decade. However, only about one‐third of patients respond to treatment, and biomarkers to predict responders are
Externí odkaz:
https://doaj.org/article/db94475297f14a02937ba2decc4f78d7
Autor:
Timothy H. Helms, Riley D. Mullins, Jennifer M. Thomas-Ahner, Samuel K. Kulp, Moray J. Campbell, Fabienne Lucas, Nathan Schmidt, Dana M. LeMoine, Surafel Getaneh, Zhiliang Xie, Mitch A. Phelps, Steven K. Clinton, Christopher C. Coss
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract A promotional role for androgen receptor (AR) signaling in hepatocellular carcinogenesis is emerging. In pre-clinical models, including diethylnitrosamine- (DEN-) induced hepatocellular carcinoma (HCC), anti-androgen therapies delay hepatoca
Externí odkaz:
https://doaj.org/article/c25b0208e10b4d27952527a2f7974c56