Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Timothy H, Holtz"'
Autor:
Sarika Pattanasin, Frits van Griensven, Philip A. Mock, Wichuda Sukwicha, Santi Winaitham, Kesinee Satumay, Siobhan O’Connor, Andrew C. Hickey, Taweesap Siraprapasiri, Joseph V. Woodring, Pachara Sirivongrangson, Timothy H. Holtz, Eileen F. Dunne
Publikováno v:
International Journal of Infectious Diseases, Vol 99, Iss , Pp 131-137 (2020)
Objectives: We assessed HIV-1 infection among men who have sex with men (MSM) attending Silom Community Clinic (SCC) in Bangkok, Thailand from 2005 to 2018. Since 2014, Thailand increased implementation of HIV prevention strategies including pre-expo
Externí odkaz:
https://doaj.org/article/c39bd80fc21b4a43a22a993d03690e52
Autor:
Sean M. Hughes, Claire N. Levy, Fernanda L. Calienes, Joanne D. Stekler, Urvashi Pandey, Lucia Vojtech, Alicia R. Berard, Kenzie Birse, Laura Noël-Romas, Brian Richardson, Jackelyn B. Golden, Michael Cartwright, Ann C. Collier, Claire E. Stevens, Marcel E. Curlin, Timothy H. Holtz, Nelly Mugo, Elizabeth Irungu, Elly Katabira, Timothy Muwonge, Javier R. Lama, Jared M. Baeten, Adam Burgener, Jairam R. Lingappa, M. Juliana McElrath, Romel Mackelprang, Ian McGowan, Ross D. Cranston, Mark J. Cameron, Florian Hladik
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 6, Pp 100096- (2020)
Summary: Tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) are used for HIV treatment and prevention. Previously, we found that topical rectal tenofovir gel caused immunological changes in the mucosa. Here, we assess the effect of oral TDF/
Externí odkaz:
https://doaj.org/article/fc2ea90cdfe548fd8b58abc0db29d044
Autor:
Kevin Weiss, Samart Karuchit, Sarika Pattanasin, Anupong Chitwarakorn, Wipas Wimonsate, Jirawat Suksamosorn, Prin Visavakum, Wichuda Sukwicha, Chaiwat Ungsedhapand, Eileen F. Dunne, Timothy H. Holtz
Publikováno v:
Geospatial Health, Vol 15, Iss 1 (2020)
Spatiotemporal analyses can support Human Immuno-deficiency Virus (HIV) prevention programmes by identifying locations of at-risk populations in space and time, and their proximity to HIV testing and prevention services. We assessed residential proxi
Externí odkaz:
https://doaj.org/article/b956d8d240814e75850e422128f5fbac
Autor:
Jill L. Schwartz, Timothy H. Holtz, Ian McGowan, Craig W. Hendrix, Marcel E. Curlin, Mark A. Marzinke, Gustavo F. Doncel, Ratiya Pamela Kunjara Na Ayudhya, Rhonda M. Brand, James F. Rooney, Boonyos Raengsakulrach, Anupong Chitwarakorn, Ross D Cranston, Jeanna M. Piper, Sherri Johnson
Publikováno v:
AIDS Res Hum Retroviruses
The Microbicide Trials Network-017 study was undertaken to characterize the safety, acceptability, pharmacokinetic (PK), and pharmacodynamic profile of the reduced-glycerin (RG) 1% tenofovir (RG-TFV) gel compared to oral emtricitabine/tenofovir disop
Autor:
James P. Hughes, Brian D. Williamson, Chloe Krakauer, Gordon Chau, Brayan Ortiz, Jon Wakefield, Craig Hendrix, K. Rivet Amico, Timothy H. Holtz, Linda‐Gail Bekker, Robert Grant
Publikováno v:
Stat Med
In trials of oral HIV pre-exposure prophylaxis (PrEP), multiple approaches have been used to measure adherence, including self-report, pill counts, electronic dose monitoring devices, and biological measures such as drug levels in plasma, peripheral
Autor:
Wanna Leelawiwat, Sarika Pattanasin, Anuwat Sriporn, Punneeporn Wasinrapee, Oranuch Kongpechsatit, Famui Mueanpai, Jaray Tongtoyai, Timothy H Holtz, Marcel E Curlin
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201386 (2018)
BACKGROUND:Differences between HIV genotypes may affect HIV disease progression. We examined infecting HIV genotypes and their association with disease progression in a cohort of men who have sex with men with incident HIV infection in Bangkok, Thail
Externí odkaz:
https://doaj.org/article/eb23bb70d6ad4d9fa25bce23489d20d9
Autor:
Dominique B Figueroa, Joseph Tillotson, Maoji Li, Estelle Piwowar-Manning, Craig W Hendrix, Timothy H Holtz, Kevin Bokoch, Linda-Gail Bekker, Frits van Griensven, Sharon Mannheimer, James P Hughes, Robert M Grant, Namandjé N Bumpus
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195764 (2018)
Tenofovir (TFV), a nucleotide reverse transcriptase inhibitor, requires two phosphorylation steps to form a competitive inhibitor of HIV reverse transcriptase. Adenylate kinase 2 (AK2) has been previously demonstrated to phosphorylate tenofovir to te
Externí odkaz:
https://doaj.org/article/5c4afdf43275489faacaf0ba13a21d5d
Autor:
Alex Carballo-Diéguez, Ivan C Balán, William Brown, Rebecca Giguere, Curtis Dolezal, Cheng-Shiun Leu, Mark A Marzinke, Craig W Hendrix, Jeanna M Piper, Barbra A Richardson, Cynthia Grossman, Sherri Johnson, Kailazarid Gomez, Stephanie Horn, Ratiya Pamela Kunjara Na Ayudhya, Karen Patterson, Cindy Jacobson, Linda-Gail Bekker, Suwat Chariyalertsak, Anupong Chitwarakorn, Pedro Gonzales, Timothy H Holtz, Albert Liu, Kenneth H Mayer, Carmen Zorrilla, Javier Lama, Ian McGowan, Ross D Cranston
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181607 (2017)
Trials to assess microbicide safety require strict adherence to prescribed regimens. If adherence is suboptimal, safety cannot be adequately assessed. MTN-017 was a phase 2, randomized sequence, open-label, expanded safety and acceptability crossover
Externí odkaz:
https://doaj.org/article/8958a3b5e21d4547a26797f9d40b2f47
Autor:
Chaiwat Ungsedhapand, Wichuda Sukwicha, Anupong Chitwarakorn, Timothy H. Holtz, Philip A. Mock, Sarika Pattanasin, Pachara Sirivongrangson, Eileen F. Dunne, Wannee Chonwattana, Jaray Tongtoyai
Publikováno v:
International Journal of STD & AIDS. 31:533-540
We analyzed the incidence and predictors of symptomatic repeat Neisseria gonorrhoeae (NG) infection among men who have sex with men (MSM) enrolled in the Bangkok MSM Cohort Study. Thai MSM aged ≥18 years were enrolled during 2006–2010 and followe
Autor:
Brian W. Weir, Chen Dun, Andrea L. Wirtz, Sandra Hsu Hnin Mon, Noor Qaragholi, Tareerat Chemnasiri, Sarika Pattanasin, Wichuda Sukwicha, Anchalee Varangrat, Eileen F. Dunne, Timothy H. Holtz, Surang Janyam, Harry Jin, Danai Linjongrat, Philip A. Mock, Michael C. Thigpen, James F. Rooney, Patrick S. Sullivan, Andrew C. Hickey, Pachara Sirivongrangson, Chris Beyrer
Publikováno v:
Ann Epidemiol
PURPOSE: To examine how recent sex work is identified and the HIV risk factors and service needs among Thai cisgender men who have sex with men (MSM) and transgender women (TGW) who exchange sex. METHODS: MSM and TGW in Bangkok and Pattaya who exchan