Výsledky vyhledávání - "Timothy Gross"

Akademický článek

Expanded Autoantibody Profiles for Subsetting of Native American, African American, and European American Patients With Systemic Lupus Erythematosus

Autor: Carla J. Guthridge, Timothy Gross, Magdalene Quintero, Joseph M. Kheir, Jeremy Levin, Rebecka L. Bourn, Sohail Khan, Michael Peercy, Bobby Saunkeah, Joel M. Guthridge, Judith A. James

Publikováno v: ACR Open Rheumatology, Vol 2, Iss 7, Pp 415-423 (2020)

Objective Many Native American (NA) patients with systemic lupus erythematosus (SLE) do not exhibit the classical SLE autoantibody profiles of European American (EA) and African American (AA) patients with SLE. The poorer SLE disease outcomes noted i

Externí odkaz: https://doaj.org/article/f4173b38869d4366b8c931a5b24c32da

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Akademický článek

Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study

Autor: Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. Macwana, Rebecka L. Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F. Chakravarty, Joan T. Merrill, Judith A. James

Publikováno v: EClinicalMedicine, Vol 20, Iss , Pp - (2020)

Background: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learni

Externí odkaz: https://doaj.org/article/cb790d3c24634179a0061b64ef7c3855

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Expanded Autoantibody Profiles for Subsetting of Native American, African American, and European American Patients With Systemic Lupus Erythematosus

Autor: Bobby Saunkeah, Rebecka L. Bourn, Joseph M Kheir, Judith A. James, Sohail Khan, Joel M. Guthridge, Jeremy Levin, Timothy Gross, Magdalene Quintero, Michael T. Peercy, Carla J. Guthridge

Publikováno v: ACR Open Rheumatology, Vol 2, Iss 7, Pp 415-423 (2020)
ACR Open Rheumatology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22bec9808ca5433ecc90c6b4dd63bf20
https://doaj.org/article/f4173b38869d4366b8c931a5b24c32da

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Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model

Autor: Latisha Heinlen, Micah T. McClain, Neelakshi R. Jog, Joel M. Guthridge, Judith A. James, Rheal A. Towner, Timothy Gross, Robert C. Axtell, John B. Harley, Gabriel Pardo

Publikováno v: J Autoimmun

Multiple sclerosis (MS) is an autoimmune demyelinating disease with progressive neurodegeneration and complex etiology likely involving genetic and environmental factors. MS has been associated with Epstein Barr virus (EBV) infection, with patients o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3f0215658d96da3a2f92624bd0ffa1
https://doi.org/10.1016/j.jaut.2019.102332

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Unique clinical characteristics, autoantibodies and medication use in Native American patients with systemic lupus erythematosus

Autor: John B. Harley, Adriana Rojas Villarraga, Daniel J. Wallace, Juan-Manuel Anaya, Michael H. Weisman, James N. Jarvis, Jonathon R Johnston, Carla J. Guthridge, Joseph M Kheir, Judith A. James, Joel M. Guthridge, Kathy L. Sivils, Melissa E. Munroe, Rebecka L. Bourn, Timothy Gross, Lucas J. Adams, Astrid Rasmussen

Publikováno v: Lupus Science & Medicine
Manuel, F., Ugarte-Gil, G.J.P.-E., Alarcon, G.S., Epidemiology (2016) Systemic Lupus Erythematosus
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

Objective: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease with varied morbidity and mortality. We assessed clinical presentations, autoantibody specificities and therapeutic interventions in Native American (NA) patients with SLE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a235e1204c3b28a77fc16af4219eee7
http://europepmc.org/articles/PMC5844376

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Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients

Autor: Bassam Hallis, Judith A. James, A. Darise Farris, Limone C. Collins, Renata J.M. Engler, Lance Pate, Hannah Cuthbertson, Christina E. Spooner, Jason L. Larabee, Sue Charlton, Timothy Gross, Hua Chen, Eric K. Dumas, Jimmy D. Ballard

Publikováno v: Clinical and vaccine immunology : CVI. 24(11)

Edema toxin (ET), composed of edema factor (EF) and protective antigen (PA), is a virulence factor of Bacillus anthracis that alters host immune cell function and contributes to anthrax disease. Anthrax vaccine precipitated (AVP) contains low but det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9699ea46e5203248a87dd9baee8f2e41
https://pubmed.ncbi.nlm.nih.gov/28877928

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Prolidase deficiency breaks tolerance to lupus-associated antigens

Autor: Judith A. James, Jacen S. Maier-Moore, Biji T. Kurien, Isaac T.W. Harley, Timothy Gross, R. Hal Scofield, Benjamin F. Bruner, Ira N. Targoff, Heng Wang, Anil D'Sousa

Publikováno v: International Journal of Rheumatic Diseases. 16:674-680

Aim Prolidase deficiency is a rare autosomal recessive disease in which one of the last steps of collagen metabolism, cleavage of proline-containing dipeptides, is impaired. Only about 93 patients have been reported with about 10% also having systemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42970dac3711082d1946885580da34ca
https://doi.org/10.1111/1756-185x.12254

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Archaeological Identification of an Idiosyncratic Lifestyle: Excavation and Analysis of the Theosophical Society Dump, San Diego, California

Autor: G. Timothy Gross, Stephen R. Van Wormer

Publikováno v: Historical Archaeology. 40:100-118

Refuse deposited by members of the Theosophical Institute in San Diego, California, ca. 1900–1920 provides a basis for defining patterns that reflect the idiosyncratic lifeways of the people who lived there. Comparisons with assemblages from urban

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb352b34252b730c1f5d6cba864b656a
https://doi.org/10.1007/bf03376717

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Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response

Autor: Micah T. McClain, Carol S. Lutz, Kenneth M. Kaufman, Judith A. James, Timothy Gross, Ofer Z. Faig

Publikováno v: Proceedings of the National Academy of Sciences. 101:3551-3556

A subset of lupus patients with severe nephritis and anti-nRNP reactivity produces autoantibodies primarily against two major epitopes of the nRNP A (also known as U1A) protein. These sequences span amino acids 44-56 (A3) and amino acids 103-115 (A6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8466239645e2641619a2b4aa00b4222
https://doi.org/10.1073/pnas.0306267101

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