Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Timothy G. Connolly"'
Autor:
Michael E. Colvin, Yuhui Huang, Xingyuan Shen, Timothy G. Connolly, Jennifer Q. Lu, Changchun Wang
Publikováno v:
Macromolecular Rapid Communications. 37:1904-1911
A low-energy triggered switch that can generate mechanoresponse has great technological potential. A submolecular moiety, S-dibenzocyclooctadiene (DBCOD) that is composed of a flexible eight-membered ring connecting to a phenyl ring at each end, unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7318d6fe80fbb96c1186b0028892cde4
https://doi.org/10.1002/marc.201600045
https://doi.org/10.1002/marc.201600045
Publikováno v:
Biophysical Journal. 110:644a
Proteins exist along a continuum from order to disorder, and many are now known to contain both folded and unfolded regions. Molecular dynamics (MD) simulations of intrinsically disordered proteins reveal deficiencies in most current analysis tools.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e87e359061a07f087f57b972dd11b54
https://doi.org/10.1016/j.bpj.2015.11.3445
https://doi.org/10.1016/j.bpj.2015.11.3445
Autor:
Amanda Miguel, Michael E. Colvin, Robert L. Wang, Ajay Gopinathan, Joshua L. Phillips, Timothy G. Connolly, Shawn Newsam
Publikováno v:
Biophysical Journal. 106:610a-611a
Intrinsically disordered proteins (IDPs) exist in a naturally unfolded state consisting of a vast ensemble of transient conformations. Molecular dynamics (MD) simulations of IDPs are capable of estimating subsets of these ensembles, but most current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4574dcc4f045d15024efb84d3cb0f6d
https://doi.org/10.1016/j.bpj.2013.11.3377
https://doi.org/10.1016/j.bpj.2013.11.3377
Autor:
Michael E. Colvin, Joshua L. Phillips, Edmond Y. Lau, Robert L. Wang, Timothy G. Connolly, Amanda Miguel
Publikováno v:
Biophysical Journal. 104:233a-234a
The nuclear pore complex (NPC) is a massive protein structure located on the nuclear envelope serving as a selective gateway between the cellular cytoplasm and nucleoplasm. The NPC is composed of numerous protein subunits referred to as nucleoporins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f27f4c7865de3ab6e3e59c0b6bb4f3
https://doi.org/10.1016/j.bpj.2012.11.1318
https://doi.org/10.1016/j.bpj.2012.11.1318
Autor:
Michael E. Colvin, Ajay Gopinathan, Timothy G. Connolly, Robert L. Wang, David Ando, Shawn Newsam
Publikováno v:
Biophysical Journal. 106:608a
Analysis tools optimized to study molecular dynamics (MD) simulations of intrinsically disordered proteins (IDPs) are currently rare. We are developing a set of tools using the libraries and interface of the widely used MD simulation software Gromacs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4cbdd6ba909cccb22dc9ed39909a733
https://doi.org/10.1016/j.bpj.2013.11.3363
https://doi.org/10.1016/j.bpj.2013.11.3363