Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Timothy G, Whitsett"'
Autor:
Joanna Palade, Eric Alsop, Amanda Courtright-Lim, Michael Hsieh, Timothy G. Whitsett, Douglas Galasko, Kendall Van Keuren-Jensen
Publikováno v:
Cells, Vol 13, Iss 3, p 207 (2024)
Alzheimer’s disease (AD), due to its multifactorial nature and complex etiology, poses challenges for research, diagnosis, and treatment, and impacts millions worldwide. To address the need for minimally invasive, repeatable measures that aid in AD
Externí odkaz:
https://doaj.org/article/581103a7fe9442c4802df3a9909af58d
Autor:
Elizabeth Hutchins, Rebecca Reiman, Joseph Winarta, Taylor Beecroft, Ryan Richholt, Matt De Both, Khalouk Shahbander, Elizabeth Carlson, Alex Janss, Ashley Siniard, Chris Balak, Ryan Bruhns, Timothy G. Whitsett, Roger McCoy, Matthew Anastasi, April Allen, Brian Churas, Matthew Huentelman, Kendall Van Keuren-Jensen
Publikováno v:
Scientific Data, Vol 8, Iss 1, Pp 1-12 (2021)
Measurement(s) transcriptome • RNA(circular) Technology Type(s) RNA sequencing Factor Type(s) biofluid Sample Characteristic - Organism Homo sapiens Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.
Externí odkaz:
https://doaj.org/article/3f23b0bd131144e3863a8b03a281779c
Autor:
Eric Alsop, Bessie Meechoovet, Robert Kitchen, Thadryan Sweeney, Thomas G. Beach, Geidy E. Serrano, Elizabeth Hutchins, Ionita Ghiran, Rebecca Reiman, Michael Syring, Michael Hsieh, Amanda Courtright-Lim, Nedyalka Valkov, Timothy G. Whitsett, Jorge Rakela, Paul Pockros, Joel Rozowsky, Juan Gallego, Matthew J. Huentelman, Ravi Shah, Peter Nakaji, M. Yashar S. Kalani, Louise Laurent, Saumya Das, Kendall Van Keuren-Jensen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
One promising goal for utilizing the molecular information circulating in biofluids is the discovery of clinically useful biomarkers. Extracellular RNAs (exRNAs) are one of the most diverse classes of molecular cargo, easily assayed by sequencing and
Externí odkaz:
https://doaj.org/article/0babcdfa00aa4ff999b84801b2a32992
Autor:
Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Timothy G Whitsett, Jeffrey A Winkles, Walter N Hittelman, Michael G Rosenblum
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Antibody-drug conjugates are an exceptional and useful therapeutic tool for multiple diseases, particularly for cancer treatment. We previously showed that the fusion of the serine protease granzyme B (GrB), the effector molecule or T and
Externí odkaz:
https://doaj.org/article/12c629aa49a34d43add526d6194f842b
Autor:
Rodosthenis S. Rodosthenous, Elizabeth Hutchins, Rebecca Reiman, Ashish S. Yeri, Srimeenakshi Srinivasan, Timothy G. Whitsett, Ionita Ghiran, Michael G. Silverman, Louise C. Laurent, Kendall Van Keuren-Jensen, Saumya Das
Publikováno v:
iScience, Vol 23, Iss 6, Pp 101182- (2020)
Summary: The recent discovery of extracellular RNAs in blood, including RNAs in extracellular vesicles (EVs), combined with low-input RNA-sequencing advances have enabled scientists to investigate their role in human disease. To date, most studies ha
Externí odkaz:
https://doaj.org/article/3990f5bfe0ea4c04a111b10538130443
Autor:
M. Yashar S. Kalani, Eric Alsop, Bessie Meechoovet, Taylor Beecroft, Komal Agrawal, Timothy G. Whitsett, Matthew J. Huentelman, Robert F. Spetzler, Peter Nakaji, Seungchan Kim, Kendall Van Keuren-Jensen
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Rapid identification of patients suffering from cerebral ischaemia, while excluding intracerebral haemorrhage, can assist with patient triage and expand patient access to chemical and mechanical revascularization. We sought to identify blood-based, e
Externí odkaz:
https://doaj.org/article/df28f35c2c89457d889a105785da6713
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec0a9510f54b6ae66360065bfb6d873d
https://doi.org/10.1158/1541-7786.22516534
https://doi.org/10.1158/1541-7786.22516534
Autor:
Nhan L. Tran, Glen J. Weiss, Janine LoBello, Chao Sima, Michael Bittner, William E. Pierceall, Ryan J. Lena, Michael H. Cardone, Ian T. Mathews, Timothy G. Whitsett
PDF file - 98K, Bcl-xL depletion sensitizes lung cancer cells to therapeutic insult but does not fully rescue TWEAK-induced cell survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b17eec1b71a8827a40146a1d01f57a
https://doi.org/10.1158/1541-7786.22511662
https://doi.org/10.1158/1541-7786.22511662
Autor:
Nhan L. Tran, Glen J. Weiss, Janine LoBello, Chao Sima, Michael Bittner, William E. Pierceall, Ryan J. Lena, Michael H. Cardone, Ian T. Mathews, Timothy G. Whitsett
PDF file - 26K, Chemical scaffold structure of EU5148.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb142abaa77ec8f5d25abcef15fa029
https://doi.org/10.1158/1541-7786.22511674
https://doi.org/10.1158/1541-7786.22511674
Autor:
Nhan L. Tran, Glen J. Weiss, Janine LoBello, Chao Sima, Michael Bittner, William E. Pierceall, Ryan J. Lena, Michael H. Cardone, Ian T. Mathews, Timothy G. Whitsett
PDF file - 159K, Mcl-1 and Fn14 gene expressions correlate in squamous cell lung carcinoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1755d9a0f7351dbcd7acb8d62132b900
https://doi.org/10.1158/1541-7786.22511671.v1
https://doi.org/10.1158/1541-7786.22511671.v1