Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Timothy G, Curran"'
Autor:
Joshua A Jadwin, Dongmyung Oh, Timothy G Curran, Mari Ogiue-Ikeda, Lin Jia, Forest M White, Kazuya Machida, Ji Yu, Bruce J Mayer
Publikováno v:
eLife, Vol 5 (2016)
While the affinities and specificities of SH2 domain-phosphotyrosine interactions have been well characterized, spatio-temporal changes in phosphosite availability in response to signals, and their impact on recruitment of SH2-containing proteins in
Externí odkaz:
https://doaj.org/article/1fdecacfc0a547c680275964c20c628e
Publikováno v:
Journal of Biological Chemistry. 293:623-637
Phosphotyrosine (pTyr)-dependent signaling is critical for many cellular processes. It is highly dynamic, as signal output depends not only on phosphorylation and dephosphorylation rates but also on the rates of binding and dissociation of effectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac55f9e573f94673f2c18887a5d09e45
https://doi.org/10.1074/jbc.m117.794412
https://doi.org/10.1074/jbc.m117.794412
Publikováno v:
The Journal of biological chemistry. 293(2)
Phosphotyrosine (pTyr)-dependent signaling is critical for many cellular processes. It is highly dynamic, as signal output depends not only on phosphorylation and dephosphorylation rates but also on the rates of binding and dissociation of effectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f0e9f0cfabdd4bca65e8df938edd2314
https://pubmed.ncbi.nlm.nih.gov/29162725
https://pubmed.ncbi.nlm.nih.gov/29162725
Autor:
Timothy G. Curran, Leila Pirhaji, Forest M. White, Pamela Milani, Alan Saghatelian, Julian Avila-Pacheco, Ernest Fraenkel, Mathias Leidl, Clary B. Clish
Publikováno v:
PMC
Uncovering the molecular context of dysregulated metabolites is crucial to understand pathogenic pathways. However, their system-level analysis has been limited owing to challenges in global metabolite identification. Most metabolite features detecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c29358c5ef0bc9d8a39ff665ce8b0e
https://orcid.org/0000-0003-0250-0474
https://orcid.org/0000-0003-0250-0474
Autor:
Lin Jia, Ji Yu, Mari Ogiue-Ikeda, Forest M. White, Joshua A. Jadwin, Timothy G. Curran, Kazuya Machida, Bruce J. Mayer, Dongmyung Oh
Publikováno v:
eLife, Vol 5 (2016)
eLife Sciences Publications, Ltd.
eLife
eLife Sciences Publications, Ltd.
eLife
While the affinities and specificities of SH2 domain-phosphotyrosine interactions have been well characterized, spatio-temporal changes in phosphosite availability in response to signals, and their impact on recruitment of SH2-containing proteins in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d39dd35ff7bb1b8f067050cd23e0ac
https://elifesciences.org/articles/11835
https://elifesciences.org/articles/11835
Autor:
Aaron Gajadhar, Daniel A. Rothenberg, Raven J. Reddy, Eric J. Swenson, Timothy G. Curran, Forest M. White
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 113(11)
Despite extensive study of the EGF receptor (EGFR) signaling network, the immediate posttranslational changes that occur in response to growth factor stimulation remain poorly characterized; as a result, the biological mechanisms underlying signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b369d487cc900dbb12da752daa5cf871
https://pubmed.ncbi.nlm.nih.gov/26929352
https://pubmed.ncbi.nlm.nih.gov/26929352
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1410
Mass spectrometry, when coupled to on-line separation such as liquid chromatography or capillary electrophoresis, enables the identification and quantification of protein expression and post-translational modification changes under diverse conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b80d166d2b434cf9c87a7c71d73c3507
https://pubmed.ncbi.nlm.nih.gov/26867751
https://pubmed.ncbi.nlm.nih.gov/26867751
Publikováno v:
Methods in Molecular Biology ISBN: 9781493935222
Mass spectrometry, when coupled to on-line separation such as liquid chromatography or capillary electrophoresis, enables the identification and quantification of protein expression and post-translational modification changes under diverse conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a317d66d79f29ea112caac5376c3226c
https://doi.org/10.1007/978-1-4939-3524-6_17
https://doi.org/10.1007/978-1-4939-3524-6_17
Publikováno v:
Nature communications
Absolute quantification of protein expression and post-translational modifications by mass spectrometry has been challenging due to a variety of factors, including the potentially large dynamic range of phosphorylation response. To address these issu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b157bc5767e76e068f2b1f4a4dfa0929
https://pubmed.ncbi.nlm.nih.gov/25581283
https://pubmed.ncbi.nlm.nih.gov/25581283