Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Timothy Francis Cloughesy"'
Autor:
Ethan A Wetzel, Matthew J Farrell, Blaine S C Eldred, Vicki Liu, Ishan Saha, Serendipity Zapanta Rinonos, Terry Prins, Tie Li, Minsong Cao, John Hegde, Tania Kaprealian, Negar Khanlou, Linda M Liau, Phioanh Leia Nghiemphu, Timothy Francis Cloughesy, Robert A Chong, Benjamin M Ellingson, Albert Lai
Publikováno v:
Neuro-Oncology Advances. 5
Background Tumor surveillance of isocitrate dehydrogenase (IDH) mutant gliomas is accomplished via serial contrast MRI. When new contrast enhancement (CEnew) is detected during postsurgical surveillance, clinicians must assess whether CEnew indicates
Autor:
Ethan Wetzel, Blaine S.C. Eldred, Vicki Liu, Serendipity Zapanta Rinonos, Negar Khanlou, Linda M. Liau, Phioanh Leia Nghiemphu, Timothy Francis Cloughesy, Benjamin M. Ellingson, Albert Lai
Publikováno v:
Journal of Clinical Oncology. 40:2043-2043
2043 Background: IDH mutant glioma patients are followed by MRI, where new contrast enhancement (CEnew) is a hallmark of tumor progression. Interpretation of CEnew is confounded by pseudoprogression (PsP), the appearance of CEnew that spontaneously r
Autor:
Patrick Y. Wen, John Frederick de Groot, James Battiste, Samuel A. Goldlust, James Stuart Garner, John Friend, Jeremy Andrew Simpson, Denise Damek, Alan Olivero, Timothy Francis Cloughesy
Publikováno v:
Journal of Clinical Oncology. 40:2047-2047
2047 Background: Paxalisib, a potent oral selective brain-penetrant small molecule PI3K/mTOR inhibitor, has shown activity in nonclinical brain cancer models and promising phase 1 data in progressive / recurrent high-grade gliomas (NCT01547546). This
Autor:
Vicki Liu, Blaine S.C. Eldred, Ethan Wetzel, Serendipity Zapanta Rinonos, Negar Khanlou, Linda M. Liau, Phioanh Leia Nghiemphu, Timothy Francis Cloughesy, Benjamin M. Ellingson, Albert Lai
Publikováno v:
Journal of Clinical Oncology. 40:2065-2065
2065 Background: Gliomas, which constitute the majority of primary brain cancers in adults, are assigned to a particular grade based on histological and molecular criteria set forth by the World Health Organization (WHO). A subset of initially low gr
Autor:
Patrick Y. Wen, Andrew J. Brenner, Nicholas A. Butowski, Tamar Rachmilewitz Minei, Dror Harats, Timothy Francis Cloughesy
Publikováno v:
Journal of Clinical Oncology. 40:TPS2075-TPS2075
TPS2075 Background: Ofranergene obadenovec (ofra-vec, VB-111) is an anti-cancer gene based immune activator and targeted vascular disruptor. The dual mechanism of action triggers a broad antiangiogenic effect and induces of a tumor directed immune re
Autor:
Phioanh Leia Nghiemphu, Hye Hyun Bahng, Albert Lai, Nadia Faiq, William H. Yong, Richard M. Green, Jonathan Polikoff, Cynthia Elizabeth Spier, Fabio Massaiti Iwamoto, Andrew B. Lassman, Timothy Francis Cloughesy
Publikováno v:
Journal of Clinical Oncology. 35:2012-2012
2012 Background: Randomized clinical trials in newly diagnosed, elderly GBM patients have shown that treatment with temozolomide chemotherapy is at least equivalent to treatment with radiotherapy. Glioblastoma in elderly patients may also have high a