Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Timothy F. Goggins"'
Autor:
Jeffrey S. Abrams, GW Sledge, CE Geyer, T. Lively, VG Kaklamani, JL Berenberg, MP Goetz, JA Olson, Joseph A. Sparano, DL Toppmeyer, M. Keane, Timothy F. Goggins, Kathy S. Albain, S Paik, DF Hayes, Robert Gray, KI Pritchard, T.J. Saphner, Timothy J. Whelan, LI Wagner, Pavan S. Reddy, Peter M. Ravdin, MJ Ellis, Sunil Badve, AM Brufsky, Henry L. Gomez, William C. Wood, IA Mayer, DF Makower, EC Dees
Publikováno v:
Cancer Research. 79:GS4-07
Background: Black race is associated with worse outcomes in localized hormone receptor (HR)-positive breast cancer in population-based and in clinical trial cohorts, whether using self-identified race (Albain et al. JNCI 2009 [PMID: 19584328; Sparano
Autor:
Henry L. Gomez, George W. Sledge, Jeffrey L. Berenberg, Amir Faghih, Matthew P. Goetz, William C. Wood, John A. Olson, Maccon M. Keane, Joseph A. Sparano, Lynne I. Wagner, Virginia G. Kaklamani, Thomas James Saphner, Della F. Makower, Timothy F. Goggins, Deborah Toppmeyer, Pavan S. Reddy, Elizabeth Claire Dees, Daniel F. Hayes, Robert Gray, Timothy J. Whelan, Adam Brufsky, Matthew J. Ellis, Kathy S. Albain, Jeffrey S. Abrams, Charles E. Geyer, Tracy Lively, Ingrid A. Mayer, Sunil Badve
Publikováno v:
J Natl Cancer Inst
Background Black race is associated with worse outcomes in early breast cancer. We evaluated clinicopathologic characteristics, the 21-gene recurrence score (RS), treatment delivered, and clinical outcomes by race and ethnicity among women who partic
Autor:
Robert Gray, Christine Desbiens, Pavan S. Reddy, Elizabeth Claire Dees, Henry L. Gomez, George W. Sledge, Catalin Mahalcioiu, Daniel F. Hayes, Kathy S. Albain, John A. Olson, Charles E. Geyer, Sunil Badve, Deborah Toppmeyer, Joseph A. Sparano, William C. Wood, Matthew P. Goetz, Thomas James Saphner, Tracy Lively, Jeffrey S. Abrams, Ingrid A. Mayer, Jeffrey L. Berenberg, DF Makower, Maccon M. Keane, Virginia G. Kaklamani, Lynne I. Wagner, Timothy F. Goggins, Adam Brufsky, Matthew J. Ellis, Soonmyung Paik
Publikováno v:
JAMA Oncol
Importance A high 21-gene recurrence score (RS) by breast cancer assay is prognostic for distant recurrence of early breast cancer after local therapy and endocrine therapy alone, and for chemotherapy benefit. Objective To describe clinical outcomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49fe41cb58839ae8d294297f0a69ae6a
https://europepmc.org/articles/PMC6777230/
https://europepmc.org/articles/PMC6777230/
Autor:
Charles E. Geyer, J Zujweski, Timothy F. Goggins, Jeffrey L. Berenberg, Daniel F. Hayes, M. Keane, Kathleen I. Pritchard, Adam Brufsky, JN Atkins, IA Mayer, Deborah Toppmeyer, KS Albain, GW Sledge, Virginia G. Kaklamani, E. A. Perez, Elizabeth Claire Dees, H. L. Gomez Moreno, John A. Olson, Joseph A. Sparano, DF Makower, Richard Gray, RP Reddi
Publikováno v:
Cancer Research. 76:P2-08
Background: The Trial Assigning Individualized Options for Treatment (TAILORx) is a prospective trial evaluating the role of endocrine therapy or chemoendocrine therapy in patients 18-75 years of age with estrogen receptor (ER)-positive, HER2-negativ
Autor:
Thomas J. Saphner, George W. Sledge, Jeffrey Abrams, Maccon M. Keane, Timothy F. Goggins, John A. Olson, Virginia G. Kaklamani, Kathy S. Albain, Adam Brufsky, Peter M. Ravdin, Charles E. Geyer, Soonmyung Paik, Matthew J. Ellis, Ingrid A. Mayer, Lynne I. Wagner, Sunil Badve, Robert Gray, Henry L. Gomez Moreno, Pavan S. Reddy, Elizabeth Claire Dees, Joseph A. Sparano, Daniel F. Hayes, Deborah Toppmeyer, Tracy Lively, Kathleen I. Pritchard, Della F. Makower, Timothy J. Whelan, Jeffery L. Berenberg, William C. Wood, Matthew P. Goetz
Publikováno v:
The New England journal of medicine. 379(2)
The recurrence score based on the 21-gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy for mo
Autor:
Timothy F. Goggins, Henry L. Gomez, George W. Sledge, Adam Brufsky, Tracy Lively, Joseph A. Sparano, Thomas James Saphner, Pavan S. Reddy, Ingrid A. Mayer, Kathleen I. Pritchard, Robert Gray, Daniel F. Hayes, John A. Olson, Della F. Makower, Charles E. Geyer, Deborah Toppmeyer, Elizabeth Claire Dees, M. Keane, Kathy S. Albain, Matthew P. Goetz
Publikováno v:
Journal of Clinical Oncology. 37:503-503
503 Background: TAILORx established that endocrine therapy (ET) alone is non-inferior to adjuvant chemotherapy (CT) plus ET in EBC and a 21-gene RS of 11-25, with some benefit if ≤50 years (y) with RS 16-25 (PMID: 29860917). We evaluated whether cl
Autor:
David A. Rizzieri, Timothy F. Goggins, Gloria Broadwater, Anne W. Beaven, Keith M. Sullivan, Jeanne Palmer, Mitchell E. Horwitz, R. E. Coleman, Nelson J. Chao
Publikováno v:
Bone Marrow Transplantation. 46:847-851
Positron emission tomography (PET) in conjunction with computed tomography is a frequently used modality for staging patients with lymphoma. Utility of PET-computed tomography before or early following auto-SCT has not been as rigorously evaluated. W
Autor:
Daniel F. Hayes, Maccon M. Keane, Pavan S. Reddy, Joseph A. Sparano, Della F. Makower, Thomas James Saphner, Deborah Toppmeyer, Charles E. Geyer, Henry L. Gomez, George W. Sledge, Robert Gray, Elizabeth Claire Dees, John A. Olson, Ingrid A. Mayer, Kathleen I. Pritchard, William C. Wood, Timothy F. Goggins, Adam Brufsky, Tracy Lively, Matthew P. Goetz
Publikováno v:
Journal of Clinical Oncology. 36:LBA1-LBA1
LBA1 Background: In hormone receptor (HR)-positive, HER2-negative, axillary node (AN)-negative breast cancer, the 21-gene expression assay (Oncotype DX Recurrence Score [RS]) is prognostic for distant recurrence, prognostic for low recurrence with en
Autor:
Kathleen I. Pritchard, William C. Wood, Tom Saphner, Virginia G. Kaklamani, John A. Olson, Charles E. Geyer, E. A. Perez, Robert Gray, H. L. Gomez Moreno, Jeffrey L. Berenberg, M. Keane, Elizabeth Claire Dees, D. F. Makower, Ingrid A. Mayer, Lynne I. Wagner, Matthew J. Ellis, Peter M. Ravdin, Tracy Lively, Sunil Badve, Pavan S. Reddy, Daniel F. Hayes, Soonmyung Paik, Timothy F. Goggins, J. A. Zujewski, Adam Brufsky, Kathy S. Albain, George W. Sledge, Deborah Toppmeyer, Timothy J. Whelan, JN Atkins, Joseph A. Sparano
BackgroundPrior studies with the use of a prospective–retrospective design including archival tumor samples have shown that gene-expression assays provide clinically useful prognostic information. However, a prospectively conducted study in a unifo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f52675aee132ee9fd094e4676c41e214
Autor:
Nelson J. Chao, Timothy F. Goggins
Publikováno v:
Leukemia & Lymphoma. 44:1871-1879
Graft versus Host Disease (GVHD) is the principal cause of morbidity and mortality in patients undergoing allogeneic stem cell transplant. T cell depletion has been recognized as a method of reducing the incidence of GVHD in allogeneic transplants. U