Zobrazeno 1 - 10
of 460
pro vyhledávání: '"Timothy F Murphy"'
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158689 (2016)
Moraxella catarrhalis is a human respiratory tract pathogen that causes otitis media (middle ear infections) in children and respiratory tract infections in adults with chronic obstructive pulmonary disease. In view of the huge global burden of disea
Externí odkaz:
https://doaj.org/article/a05a25a542b04301b5d9130ee2180f43
Autor:
Lixin Zhang, Jingping Xie, Mayuri Patel, Arsala Bakhtyar, Garth D Ehrlich, Azad Ahmed, Josh Earl, Carl F Marrs, Daniel Clemans, Timothy F Murphy, Janet R Gilsdorf
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44730 (2012)
BackgroundHaemophilus influenzae (Hi) colonizes the human respiratory tract and is an important pathogen associated with chronic obstructive pulmonary disease (COPD). Bacterial factors that interact with the human host may be important in the pathoge
Externí odkaz:
https://doaj.org/article/86e36140375842389a45b4a3ba0d2ad5
Autor:
Shigeki Nakamura, Mikhail Shchepetov, Ankur B Dalia, Sarah E Clark, Timothy F Murphy, Sanjay Sethi, Janet R Gilsdorf, Arnold L Smith, Jeffery N Weiser
Publikováno v:
PLoS Pathogens, Vol 7, Iss 1, p e1001247 (2011)
Non-typeable Haemophilus influenzae (NTHi), a common commensal of the human pharynx, is also an opportunistic pathogen if it becomes established in the lower respiratory tract (LRT). In comparison to colonizing isolates from the upper airway, LRT iso
Externí odkaz:
https://doaj.org/article/9806c738542d4207b696a2f348e0ca03
Autor:
Timothy F Murphy, Alan J Lesse, Charmaine Kirkham, Huachun Zhong, Sanjay Sethi, Robert S Munson
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25923 (2011)
Strains of nontypeable Haemophilus influenzae show enormous genetic heterogeneity and display differential virulence potential in different clinical settings. The igaB gene, which encodes a newly identified IgA protease, is more likely to be present
Externí odkaz:
https://doaj.org/article/c4080936e42b4dba95d5f03677c2e082
Autor:
Amit A Lugade, Anna Bianchi-Smiraglia, Vandana Pradhan, Galina Elkin, Timothy F Murphy, Yasmin Thanavala
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19781 (2011)
The cross-talk between the innate and the adaptive immune system is facilitated by the initial interaction of antigen with dendritic cells. As DCs express a large array of TLRs, evidence has accumulated that engagement of these molecules contributes
Externí odkaz:
https://doaj.org/article/09afa13a783a498893b7258e41420d33
Publikováno v:
Journal of Clinical and Translational Science, Vol 8 (2024)
Abstract Introduction: Despite the central importance of cross-disciplinary collaboration in the Clinical and Translational Science Award (CTSA) network and the implementation of various programs designed to enhance collaboration, rigorous evidence
Externí odkaz:
https://doaj.org/article/c3fde108fa934051a950f6922273c6a5
Autor:
Timothy F. Murphy, Charmaine Kirkham, Adonis D’Mello, Sanjay Sethi, Melinda M. Pettigrew, Hervé Tettelin
Publikováno v:
mBio, Vol 14, Iss 2 (2023)
ABSTRACT Chronic obstructive pulmonary disease (COPD) is a common debilitating disorder that is the third most common cause of death globally. Chronic lower airway infection by nontypeable Haemophilus influenzae (NTHi) in adults with COPD increases a
Externí odkaz:
https://doaj.org/article/20146d186fb44684a1a1a02643d4db83
Autor:
Eishika Dissanayake, Rebecca A. Brockman-Schneider, Reed M. Stubbendieck, Britney A. Helling, Zhumin Zhang, Yury A. Bochkov, Charmaine Kirkham, Timothy F. Murphy, Carole Ober, Cameron R. Currie, James E. Gern
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Rhinovirus causes many types of respiratory illnesses, ranging from minor colds to exacerbations of asthma. Moraxella catarrhalis is an opportunistic pathogen that is increased in abundance during rhinovirus illnesses and asthma exacerbations and is
Externí odkaz:
https://doaj.org/article/f8d33749490d4a6caf34ee0a914cf831
Autor:
Timothy F. Murphy
A critical review of the debate over the still-hypothetical possibility of prenatal intervention by parents to select the sexual orientation of their children.Parents routinely turn to prenatal testing to screen for genetic or chromosomal disorders o
Autor:
Elizabeth Bengert, Katia Noyes, Lorin Towle-Miller, Joseph Boccardo, Geoffrey Mercene, Patricia J. Ohtake, Prasad Balkundi, Peter L. Elkin, Joseph Balthasar, Timothy F. Murphy
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 129-129 (2023)
OBJECTIVES/GOALS: This study proposes a pragmatic approach for tracking institutional changes in research teamwork and productivity in real time using common institutional electronic databases such as eCV and grant management systems. Dissemination o
Externí odkaz:
https://doaj.org/article/6931e90fae6c4a20a8cfbc82c93b649c