Mycobacterium tuberculosis transmission in Birmingham, UK, 2009–19: An observational study

Autor: Timothy M. Walker, Marc Choisy, Martin Dedicoat, Philip G. Drennan, David Wyllie, Fan Yang-Turner, Derrick W. Crook, Esther R. Robinson, A. Sarah Walker, E. Grace Smith, Timothy E.A. Peto

Publikováno v: The Lancet Regional Health. Europe, Vol 17, Iss , Pp 100361- (2022)

Summary: Background: Over 10-years of whole-genome sequencing (WGS) of Mycobacterium tuberculosis in Birmingham presents an opportunity to explore epidemiological trends and risk factors for transmission in new detail. Methods: Between 1st January 20

Externí odkaz: https://doaj.org/article/13eef50fadca4ce9b28472263658888f

HIV/AIDS

Autor: Sarah Fidler, Timothy E.A. Peto, Philip Goulder, Christopher P. Conlon

Since its discovery in 1983, the human immunodeficiency virus (HIV) has been associated with a global pandemic that has affected more than 78 million people and caused more than 39 million deaths. Globally, 36.9 million (34.3–41.4 million) people w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cdc071f39a8802f391db1d2644c94f5
https://doi.org/10.1093/med/9780198746690.003.0098

GenomegaMap: within-species genome-widedN/dSestimation from over 10,000 genomes

Autor: Wilson, DJ, Crook, DW, Peto, TEA, Walker, AS, Hoosdally, SJ, Gibertoni Cruz, AL, Carter, J, Grazian, C, Earle, SG, Kouchaki, S, Lachapelle, A, Yang, Y, Clifton, DA, Fowler, PW, Iqbal, Z, Hunt, M, Knaggs, J, Smith, EG, Rathod, P, Jarrett, L, Matias, D, Cirillo, DM, Borroni, E, Battaglia, S, Ghodousi, A, Spitaleri, A, Cabibbe, A, Tahseen, S, Nilgiriwala, K, Shah, S, Rodrigues, C, Kambli, P, Surve, U, Khot, R, Niemann, S, Kohl, TA, Merker, M, Hoffmann, H, Todt, K, Plesnik, S, Ismail, N, Omar, SV, Joseph, L, Thwaites, G, Thuong, TNT, Ngoc, NH, Srinivasan, V, Walker, TM, Moore, D, Coronel, J, Solano, W, Gao, GF, He, G, Zhao, Y, Liu, C, Ma, A, Zhu, B, Laurenson, I, Claxton, P, Koch, A, Wilkinson, R, Lalvani, A, Posey, J, Gardy, J, Werngren, J, Paton, N, Jou, R, Wu, M-H, Lin, W-H, Ferrazoli, L, De Oliveira, RS, Arandjelovic, I, Chaiprasert, A, Comas, I, Roig, CJ, Drobniewski, FA, Farhat, MR, Gao, Q, Hee, ROT, Sintchenko, V, Supply, P, Van Soolingen, D

Publikováno v: Molecular Biology and Evolution
Molecular Biology and Evolution, 2020, 37 (8), pp.2450-2460. ⟨10.1093/molbev/msaa069⟩
Molecular Biology and Evolution, Oxford University Press (OUP), 2020, 37 (8), pp.2450-2460. ⟨10.1093/molbev/msaa069⟩
Digital.CSIC. Repositorio Institucional del CSIC
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11 págs, 4 figuras y fórmulas matemáticas. Material suplementario en: http://dx.doi.org/10.1093/molbev/msaa069
The dN/dS ratio provides evidence of adaptation or functional constraint in protein-coding genes by quantifying the relative excess

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f28734013613db456521c1a9a29560
https://doi.org/10.1101/523316