Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Timothy E. Richardson"'
Autor:
Meenakshi Vij, Benjamin B. Cho, Raquel T. Yokoda, Omid Rashidipour, Melissa Umphlett, Timothy E. Richardson, Nadejda M. Tsankova
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Molecular characterization of gliomas has uncovered genomic signatures with significant impact on tumor diagnosis and prognostication. CDKN2A is a tumor suppressor gene involved in cell cycle control. Homozygous deletion of the CDKN2A/B locu
Externí odkaz:
https://doaj.org/article/c577778d01c944589b9ed8e594c91f0b
Autor:
Gabriel A. Marx, Daniel G. Koenigsberg, Andrew T. McKenzie, Justin Kauffman, Russell W. Hanson, Kristen Whitney, Maxim Signaevsky, Marcel Prastawa, Megan A. Iida, Charles L. White, Jamie M. Walker, Timothy E. Richardson, John Koll, Gerardo Fernandez, Jack Zeineh, Carlos Cordon-Cardo, John F. Crary, Kurt Farrell, The PART working group
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Tauopathies are a category of neurodegenerative diseases characterized by the presence of abnormal tau protein-containing neurofibrillary tangles (NFTs). NFTs are universally observed in aging, occurring with or without the concomitant accum
Externí odkaz:
https://doaj.org/article/e22393483aa642398a63b9e7b244d96c
Autor:
Andrew T. McKenzie, Gabriel A. Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker, Timothy E. Richardson, Gabriele Campanella, Johannes Attems, Ann C. McKee, Thor D. Stein, Thomas J. Fuchs, Charles L. White, The PART working group, Kurt Farrell, John F. Crary
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Age-related cognitive impairment is multifactorial, with numerous underlying and frequently co-morbid pathological correlates. Amyloid beta (Aβ) plays a major role in Alzheimer’s type age-related cognitive impairment, in addition to other
Externí odkaz:
https://doaj.org/article/d218b0be340e401e93dd81a56163f5e6
Autor:
Sultan M. Zain, MPH, Kanish Mirchia, MD, Kristyn Galbraith, MD, Michael A. Galgano, MD, Mijung Lee, MD, Timothy E. Richardson, DO, PhD, Kavya Mirchia, MD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 9, Pp 3339-3344 (2022)
ABSTRACT: Primary intracranial germ cell tumors are rare, occurring more frequently in children and young adults in midline locations of the brain. Teratomas are an uncommon variant of germ cell neoplasm, although they account for a high proportion o
Externí odkaz:
https://doaj.org/article/884a30ca19604a479ccc199d2c571d72
Autor:
Timothy E. Richardson, Jamie M. Walker, Kalil G. Abdullah, Samuel K. McBrayer, Mariano S. Viapiano, Zarmeen M. Mussa, Nadejda M. Tsankova, Matija Snuderl, Kimmo J. Hatanpaa
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Chromosomal instability (CIN) is a fundamental property of cancer and a key underlying mechanism of tumorigenesis and malignant progression, and has been documented in a wide variety of cancers, including colorectal carcinoma with mutations
Externí odkaz:
https://doaj.org/article/c1a71773a3f94c97b197440a1074044c
Autor:
Lilly W. Tang, Arka N. Mallela, Hansen Deng, Timothy E. Richardson, Shawn L. Hervey-Jumper, Samuel K. McBrayer, Kalil G. Abdullah
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Models for human gliomas prove critical not only to advancing our understanding of glioma biology but also to facilitate the development of therapeutic modalities. Specifically, creating lower-grade glioma (LGG) models has been challenging, contribut
Externí odkaz:
https://doaj.org/article/e11a1a02c2c24b458f0e77b541b02f81
Autor:
Yan Liu, Adwait Amod Sathe, Kalil G. Abdullah, Samuel K. McBrayer, Steven H. Adams, Andrew J. Brenner, Kimmo J. Hatanpaa, Mariano S. Viapiano, Chao Xing, Jamie M. Walker, Timothy E. Richardson
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Diffusely infiltrating gliomas are among the most common central nervous system tumors in adults. Over the past decade, the subcategorization of these tumors has changed to include both traditional histologic features and more recently ident
Externí odkaz:
https://doaj.org/article/943d8c7aa6c44d918280294737c34ab0
Autor:
Jamie M. Walker, Shiva Kazempour Dehkordi, Anna Fracassi, Alison Vanschoiack, Anna Pavenko, Giulio Taglialatela, Randall Woltjer, Timothy E. Richardson, Habil Zare, Miranda E. Orr
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Clinical symptoms correlate with underlying neurodegenerative changes in the vast majority of people. However, an intriguing group of individuals demonstrate neuropathologic changes consistent with Alzheimer disease (AD) yet remain cognitive
Externí odkaz:
https://doaj.org/article/046be168d3ca411d8f9e2f40f79a4fb0
Autor:
Megan A. Iida, Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabriel A. Marx, Clare H. Bryce, Dushyant Purohit, Gai Ayalon, Thomas G. Beach, Eileen H. Bigio, Etty P. Cortes, Marla Gearing, Vahram Haroutunian, Corey T. McMillan, Edward B. Lee, Dennis W. Dickson, Ann C. McKee, Thor D. Stein, John Q. Trojanowski, Randall L. Woltjer, Gabor G. Kovacs, Julia K. Kofler, Jeffrey Kaye, Charles L. White, John F. Crary
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Primary age-related tauopathy (PART) is a form of Alzheimer-type neurofibrillary degeneration occurring in the absence of amyloid-beta (Aβ) plaques. While PART shares some features with Alzheimer disease (AD), such as progressive accumulati
Externí odkaz:
https://doaj.org/article/34a4f4e1641746a88e977b7cf3b9dcc5
Autor:
James F. Lyon, Varshini Vasudevaraja, Kanish Mirchia, Jamie M. Walker, Robert J. Corona, Lawrence S. Chin, Ivy Tran, Matija Snuderl, Timothy E. Richardson, Mariano S. Viapiano
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Glioblastoma (GBM) is the most common malignant primary central nervous system (CNS) neoplasm in adults, and has an almost universally poor prognosis. Recently, an emphasis on genetic and epigenetic profiling has revealed a number of molecul
Externí odkaz:
https://doaj.org/article/1057edd1b2524571a8031fe8a0347eb2