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pro vyhledávání: '"Timothy E Sparer"'
Autor:
Andrew S Wagner, Stephen W Lumsdaine, Mikayla M Mangrum, Ainsley E King, Trevor J Hancock, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Genetics, Vol 18, Iss 9, p e1010405 (2022)
In order to successfully induce disease, the fungal pathogen Candida albicans regulates exposure of antigens like the cell wall polysaccharide ß(1,3)-glucan to the host immune system. C. albicans covers (masks) ß(1,3)-glucan with a layer of mannosy
Externí odkaz:
https://doaj.org/article/701a003d398e45fcb66bc35c03808cc2
Autor:
Andrew S Wagner, Trevor J Hancock, Stephen W Lumsdaine, Sarah J Kauffman, Mikayla M Mangrum, Elise K Phillips, Timothy E Sparer, Todd B Reynolds
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009839 (2021)
Masking the immunogenic cell wall epitope ß(1,3)-glucan under an outer layer of mannosylated glycoproteins is an important virulence factor deployed by Candida albicans during infection. Consequently, increased ß(1,3)-glucan exposure (unmasking) re
Externí odkaz:
https://doaj.org/article/cdfab09a60b748168be22f81e6fb3981
Publikováno v:
PLoS Genetics, Vol 15, Iss 1, p e1007892 (2019)
Candida albicans is among the most common causes of human fungal infections and is an important source of mortality. C. albicans is able to diminish its detection by innate immune cells through masking of β (1,3)-glucan in the inner cell wall with a
Externí odkaz:
https://doaj.org/article/316262bab3db4661a89e3080d7bdc96d