Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Timothy E Schlub"'
Autor:
Peter J McCluskey, Thomas Hong, Andrew A Chang, John Grigg, Geoffrey K Broadhead, Timothy E Schlub, Eugenia Chu
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss 1 (2024)
Objective To assess the long-term efficacy and safety of oral saffron, a natural antioxidant, in treating mild/moderate age-related macular degeneration (AMD).Methods and analysis Open-label, extension trial of 93 adults (>50 years) with mild/moderat
Externí odkaz:
https://doaj.org/article/4bf438060ebd49eeb7eeda90d0b9e850
Autor:
Steffen S Docken, Kevin McCormick, M Betina Pampena, Sadia Samer, Emily Lindemuth, Mykola Pinkevych, Elise G Viox, Yuhuang Wu, Timothy E Schlub, Deborah Cromer, Brandon F Keele, Mirko Paiardini, Michael R Betts, Katharine J Bar, Miles P Davenport
Publikováno v:
PLoS Pathogens, Vol 19, Iss 11, p e1011755 (2023)
HIV rapidly rebounds after interruption of antiretroviral therapy (ART). HIV-specific CD8+ T cells may act to prevent early events in viral reactivation. However, the presence of viral immune escape mutations may limit the effect of CD8+ T cells on v
Externí odkaz:
https://doaj.org/article/62520ead571c4df1beba991915be4215
Autor:
Eva Stadler, Deborah Cromer, Somya Mehra, Adeshina I Adekunle, Jennifer A Flegg, Nicholas M Anstey, James A Watson, Cindy S Chu, Ivo Mueller, Leanne J Robinson, Timothy E Schlub, Miles P Davenport, David S Khoury
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 16, Iss 12, p e0010990 (2022)
A key characteristic of Plasmodium vivax parasites is their ability to adopt a latent liver-stage form called hypnozoites, able to cause relapse of infection months or years after a primary infection. Relapses of infection through hypnozoite activati
Externí odkaz:
https://doaj.org/article/19bc54aa08ff458091d20a0201a490c6
Autor:
Deborah Cromer, PhD, Megan Steain, PhD, Arnold Reynaldi, PhD, Timothy E Schlub, PhD, Adam K Wheatley, PhD, Jennifer A Juno, PhD, Stephen J Kent, MD, James A Triccas, PhD, David S Khoury, PhD, Miles P Davenport, DPhil
Publikováno v:
The Lancet Microbe, Vol 3, Iss 1, Pp e52-e61 (2022)
Summary: Background: Several SARS-CoV-2 variants of concern have been identified that partly escape serum neutralisation elicited by current vaccines. Studies have also shown that vaccines demonstrate reduced protection against symptomatic infection
Externí odkaz:
https://doaj.org/article/23977c96b0e84581a0a9625eb4ecfd5a
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0150991 (2016)
Quantifying the spatial scale of population connectivity is important for understanding the evolutionary potential of ecologically divergent populations and for designing conservation strategies to preserve those populations. For marine organisms lik
Externí odkaz:
https://doaj.org/article/0a9264e32f1548d59ada1b4682f12fea
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 4, p e1000766 (2010)
Retroviral recombination is thought to play an important role in the generation of immune escape and multiple drug resistance by shuffling pre-existing mutations in the viral population. Current estimates of HIV-1 recombination rates are derived from
Externí odkaz:
https://doaj.org/article/91afb1af0757412a9f5ad20004a08a53
Autor:
David S. Khoury, Timothy E. Schlub, Deborah Cromer, Megan Steain, Youyi Fong, Peter B. Gilbert, Kanta Subbarao, James A. Triccas, Stephen J. Kent, Miles P. Davenport
Publikováno v:
Emerging Infectious Diseases. 29:381-388
Autor:
Deborah Cromer, Megan Steain, Arnold Reynaldi, Timothy E. Schlub, Shanchita R. Khan, Sarah C. Sasson, Stephen J. Kent, David S. Khoury, Miles P. Davenport
Publikováno v:
Nature Communications. 14
Vaccine protection from symptomatic SARS-CoV-2 infection has been shown to be strongly correlated with neutralising antibody titres; however, this has not yet been demonstrated for severe COVID-19. To explore whether this relationship also holds for
Autor:
David Thomas, Barbara B. Biesecker, David Goldstein, Nicci Bartley, Megan Best, Ilona Juraskova, Phyllis Butow, Bettina Meiser, Timothy E. Schlub, Christine E Napier, Katherine M. Tucker, Mandy L. Ballinger, Grace Davies
Publikováno v:
American Journal of Medical Genetics Part A. 188:725-734
This study assessed the psychological predictors of preferences for return of comprehensive tumor genomic profiling (CTGP) results in patients with advanced cancers, enrolled in the Molecular Screening and Therapeutics Program. Patients completed a q
Publikováno v:
Molecular Genetics & Genomic Medicine. 11
Neurofibromatosis 1 (NF1) is a common cancer predisposition syndrome. Affected individuals require lifelong surveillance and often suffer progressive disfigurement due to cutaneous neurofibromas. The aim of this research was to characterize health co