Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Timothy E Richardson"'
Autor:
Joseph D Buehler, Cylaina E Bird, Milan R Savani, Lauren C Gattie, William H Hicks, Michael M Levitt, Mohamad El Shami, Kimmo J Hatanpaa, Timothy E Richardson, Samuel K McBrayer, Kalil G Abdullah
Publikováno v:
Cancer Informatics, Vol 21 (2022)
The creation of patient-derived cancer organoids represents a key advance in preclinical modeling and has recently been applied to a variety of human solid tumor types. However, conventional methods used to assess in vivo tumor tissue treatment respo
Externí odkaz:
https://doaj.org/article/12674b086d134b5cb1505f9925a80c9f
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34600 (2012)
Estrogen and estrogen-related compounds have been shown to have very potent cytoprotective properties in a wide range of disease models, including an in vitro model of Friedreich's ataxia (FRDA). This study describes a potential estrogen receptor (ER
Externí odkaz:
https://doaj.org/article/568f552b8b9d4eecb5c9a50ed3ad2df6
Autor:
Timothy E Richardson, Karen M Chapman, Christina Tenenhaus Dann, Robert E Hammer, F Kent Hamra
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6308 (2009)
Despite remarkable advances in assisted reproductive capabilities approximately 4% of all couples remain involuntarily infertile. In almost half of these cases, a lack of conception can in some measure be attributed to the male partner, wherein de no
Externí odkaz:
https://doaj.org/article/db37524928f34a96b6e44298cb1b160f
Autor:
Gabriel A. Marx, Daniel G. Koenigsberg, Andrew T. McKenzie, Justin Kauffman, Russell W. Hanson, Kristen Whitney, Maxim Signaevsky, Marcel Prastawa, Megan A. Iida, Charles L. White, Jamie M. Walker, Timothy E. Richardson, John Koll, Gerardo Fernandez, Jack Zeineh, Carlos Cordon-Cardo, John F. Crary, Kurt Farrell, The PART working group
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-12 (2022)
Abstract Tauopathies are a category of neurodegenerative diseases characterized by the presence of abnormal tau protein-containing neurofibrillary tangles (NFTs). NFTs are universally observed in aging, occurring with or without the concomitant accum
Externí odkaz:
https://doaj.org/article/e22393483aa642398a63b9e7b244d96c
Autor:
Andrew T. McKenzie, Gabriel A. Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker, Timothy E. Richardson, Gabriele Campanella, Johannes Attems, Ann C. McKee, Thor D. Stein, Thomas J. Fuchs, Charles L. White, The PART working group, Kurt Farrell, John F. Crary
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Age-related cognitive impairment is multifactorial, with numerous underlying and frequently co-morbid pathological correlates. Amyloid beta (Aβ) plays a major role in Alzheimer’s type age-related cognitive impairment, in addition to other
Externí odkaz:
https://doaj.org/article/d218b0be340e401e93dd81a56163f5e6
Autor:
Sultan M. Zain, MPH, Kanish Mirchia, MD, Kristyn Galbraith, MD, Michael A. Galgano, MD, Mijung Lee, MD, Timothy E. Richardson, DO, PhD, Kavya Mirchia, MD
Publikováno v:
Radiology Case Reports, Vol 17, Iss 9, Pp 3339-3344 (2022)
ABSTRACT: Primary intracranial germ cell tumors are rare, occurring more frequently in children and young adults in midline locations of the brain. Teratomas are an uncommon variant of germ cell neoplasm, although they account for a high proportion o
Externí odkaz:
https://doaj.org/article/884a30ca19604a479ccc199d2c571d72
Autor:
Timothy E. Richardson, Jamie M. Walker, Kalil G. Abdullah, Samuel K. McBrayer, Mariano S. Viapiano, Zarmeen M. Mussa, Nadejda M. Tsankova, Matija Snuderl, Kimmo J. Hatanpaa
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-13 (2022)
Abstract Chromosomal instability (CIN) is a fundamental property of cancer and a key underlying mechanism of tumorigenesis and malignant progression, and has been documented in a wide variety of cancers, including colorectal carcinoma with mutations
Externí odkaz:
https://doaj.org/article/c1a71773a3f94c97b197440a1074044c
Autor:
Yan Liu, Adwait Amod Sathe, Kalil G. Abdullah, Samuel K. McBrayer, Steven H. Adams, Andrew J. Brenner, Kimmo J. Hatanpaa, Mariano S. Viapiano, Chao Xing, Jamie M. Walker, Timothy E. Richardson
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Diffusely infiltrating gliomas are among the most common central nervous system tumors in adults. Over the past decade, the subcategorization of these tumors has changed to include both traditional histologic features and more recently ident
Externí odkaz:
https://doaj.org/article/943d8c7aa6c44d918280294737c34ab0
Autor:
Jamie M. Walker, Shiva Kazempour Dehkordi, Anna Fracassi, Alison Vanschoiack, Anna Pavenko, Giulio Taglialatela, Randall Woltjer, Timothy E. Richardson, Habil Zare, Miranda E. Orr
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-14 (2022)
Abstract Clinical symptoms correlate with underlying neurodegenerative changes in the vast majority of people. However, an intriguing group of individuals demonstrate neuropathologic changes consistent with Alzheimer disease (AD) yet remain cognitive
Externí odkaz:
https://doaj.org/article/046be168d3ca411d8f9e2f40f79a4fb0
Autor:
Megan A. Iida, Kurt Farrell, Jamie M. Walker, Timothy E. Richardson, Gabriel A. Marx, Clare H. Bryce, Dushyant Purohit, Gai Ayalon, Thomas G. Beach, Eileen H. Bigio, Etty P. Cortes, Marla Gearing, Vahram Haroutunian, Corey T. McMillan, Edward B. Lee, Dennis W. Dickson, Ann C. McKee, Thor D. Stein, John Q. Trojanowski, Randall L. Woltjer, Gabor G. Kovacs, Julia K. Kofler, Jeffrey Kaye, Charles L. White, John F. Crary
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-12 (2021)
Abstract Primary age-related tauopathy (PART) is a form of Alzheimer-type neurofibrillary degeneration occurring in the absence of amyloid-beta (Aβ) plaques. While PART shares some features with Alzheimer disease (AD), such as progressive accumulati
Externí odkaz:
https://doaj.org/article/34a4f4e1641746a88e977b7cf3b9dcc5