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of 4
pro vyhledávání: '"Timothy Donaldson"'
Autor:
Timothy Donaldson, Amanda Simcox, Jessica Price, Thomas L Jacobsen, Shu-Huei Wang, Bruce C. Schnepp
Publikováno v:
Genetics. 167:687-698
Vein (Vn), a ligand for the Drosophila epidermal growth factor receptor (Egfr), has a complex structure including a PEST, Ig, and EGF domain. We analyzed the structure-function relationships of Vn by assaying deletion mutants. The results show that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a192150f1f7572958eaf1ef756e4d2d8
https://doi.org/10.1534/genetics.103.019588
https://doi.org/10.1534/genetics.103.019588
Autor:
Amanda Simcox, Timothy Donaldson, Ben-Zion Shilo, Ronen Schweitzer, Bruce C. Schnepp, Gary Grumbling, Stephen Ostrowski
Publikováno v:
Genesdevelopment. 12(7)
In Drosophila the function of the epidermal growth factor (EGF) receptor is modulated zygotically by three EGF-like proteins: Spitz (Spi), which is a potent activator; Vein (Vn), which is a moderate activator; and Argos (Aos), which is an inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab46db5b0eb17db4f0fb4158fdfdcc61
https://pubmed.ncbi.nlm.nih.gov/9531530
https://pubmed.ncbi.nlm.nih.gov/9531530
Publikováno v:
Genesdevelopment. 10(18)
The activation signal from tyrosine kinase receptors, such as the epidermal growth factor receptor (EGFR), is relayed via a highly conserved intracellular pathway involving Ras, Raf, and MAPK. In Drosophila, the EGFR and components of the intracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71355c6c5fbe7834a58d9a4753cded0c
https://pubmed.ncbi.nlm.nih.gov/8824589
https://pubmed.ncbi.nlm.nih.gov/8824589
Publikováno v:
Developmental Biology. (1):243-259
Signaling by the Drosophila EGF receptor (DER) is modulated by four known EGF-like proteins: the agonists Vein (Vn), Spitz (Spi), and Gurken (Grk) and the antagonist Argos (Aos). DER is broadly expressed and thus tissue-specific regulation of ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b2b57bc083bc2f92597effd2684e02e